Centre For Clinical Research Excellence In Newborn Medicine
Funder
National Health and Medical Research Council
Funding Amount
$2,519,475.00
Summary
The Centre for Clinical Research Excellence in Newborn Medicine will study adverse outcomes for the brains and lungs of newborn babies; it will establish how often these occur in different types of babies (ranging from very premature babies, through to those born on time), investigate the different causes, develop treatments to either prevent or treat the adverse outcomes, determine the long-term consequences into adulthood, and continually re-evaluate the effectiveness of the various treatment ....The Centre for Clinical Research Excellence in Newborn Medicine will study adverse outcomes for the brains and lungs of newborn babies; it will establish how often these occur in different types of babies (ranging from very premature babies, through to those born on time), investigate the different causes, develop treatments to either prevent or treat the adverse outcomes, determine the long-term consequences into adulthood, and continually re-evaluate the effectiveness of the various treatment strategies designed to improve the health outcomes for newborn babies.Read moreRead less
The Centre will enhance Australian clinical immunisation research and training, focussing upon clinical questions with translatable outcomes not easily addressed by industry. Optimal immunisation and interventions to maximise uptake of existing and new vaccines in high risk patient groups, such as children with cancer, immigrants, children with chronic diseases and adolescents will be studied. New vaccine trials, innovative use of existing vaccines, systematic collection of vaccine failure data, ....The Centre will enhance Australian clinical immunisation research and training, focussing upon clinical questions with translatable outcomes not easily addressed by industry. Optimal immunisation and interventions to maximise uptake of existing and new vaccines in high risk patient groups, such as children with cancer, immigrants, children with chronic diseases and adolescents will be studied. New vaccine trials, innovative use of existing vaccines, systematic collection of vaccine failure data, and targeted epidemiology and disease modelling vaccine preventable disease will also allow a broad program of research, enabling training and mentoring of young clinical nurse and physician researchers. Collaborations with existing national immunisation, infectious diseases and research institutions will allow maximal effectiveness of clinical studies.Read moreRead less
Centre For Training In Clinical Cardiovascular And Cerebrovascular Research
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
This Centre proposes to expand its highly successful Centre of Clinical Excellence funded by NHMRC from 1998-2001. The Centre provided the opportunity in Western Australia for the highest quality clinical research training in comprehensive spheres relevant to the pathogenesis, prevention and therapeutics of cardiovascular disease, with an emphasis on the role of nutrition and lifestyle in relation to high blood pressure, arteriosclerosis, dyslipidaemia and the function of blood vessels. The new ....This Centre proposes to expand its highly successful Centre of Clinical Excellence funded by NHMRC from 1998-2001. The Centre provided the opportunity in Western Australia for the highest quality clinical research training in comprehensive spheres relevant to the pathogenesis, prevention and therapeutics of cardiovascular disease, with an emphasis on the role of nutrition and lifestyle in relation to high blood pressure, arteriosclerosis, dyslipidaemia and the function of blood vessels. The new Centre will broaden the scope of its research and training activities, through the inclusion of clinical projects related to heart failure, clinical and epidemiological research into cerebrovascular disease and stroke and research training opportunities with respect to clotting disorders and therapeutics for thrombosis.Read moreRead less
Neurosciences: Cross-Discipline Enhancement Of Clinical Research & Education
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
This Centre has developed an innovative multidisciplinary model for hospital based clinical research into the common public health problems of stroke and epilepsy. This comprises: research into mechanisms, outcome and rehabilitation of stroke and epilepsy, teaching research skills, career development, and external assessment. Clinicians, researchers and students from medicine, nursing, allied health will be involved. This approach will enhance wider dissemination of research into the community a ....This Centre has developed an innovative multidisciplinary model for hospital based clinical research into the common public health problems of stroke and epilepsy. This comprises: research into mechanisms, outcome and rehabilitation of stroke and epilepsy, teaching research skills, career development, and external assessment. Clinicians, researchers and students from medicine, nursing, allied health will be involved. This approach will enhance wider dissemination of research into the community and may provide a model for other clinical research programs.Read moreRead less
Metabolic disorders related to the modern lifestyle, including inactivity, obesity, the metabolic syndrome and type II diabetes, are responsible for a major proportion of the disease burden in Australia. Current treatment strategies are expensive and because they are directed at end-organ damage (heart failure, heart attacks etc), rather ineffective. This multispecialty, multidisciplinary group will undertake a series of unique studies aimed at understanding and preventing early cardiovascular c ....Metabolic disorders related to the modern lifestyle, including inactivity, obesity, the metabolic syndrome and type II diabetes, are responsible for a major proportion of the disease burden in Australia. Current treatment strategies are expensive and because they are directed at end-organ damage (heart failure, heart attacks etc), rather ineffective. This multispecialty, multidisciplinary group will undertake a series of unique studies aimed at understanding and preventing early cardiovascular complications of these metabolic conditions. Sensitive new cardiovascular imaging techniques will be used to detect preclinical abnormalities in the structure, function and metabolism of the heart and vasculature, facilitating the development of new strategies of exercise and lifestyle intervention to prevent these complications. While built on the successful current CCRE in Cardiovascular and Metabolic Disease, including multidisciplinary clinical research training, the new application involves major new directions in the interface between the liver and metabolic syndrome, and strategies for community-based prevention programs. The nursing intervention model, which will focus on workforce models of care, is especially important. The results of this study will provide information to address the need for different nursing models sought by the recent Productivity Commission Report.Read moreRead less
Centre Of Clinical Research Excellence In Nutritional Physiology, Interventions, And Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$2,007,200.00
Summary
Over 20% of Australian adults either have diabetes, or are at imminent risk, while 60% are overweight or obese. Conversely, some 40% of the elderly receiving domiciliary support are at risk of malnutrition. Poor nutrition underpins numerous chronic diseases. We seek to capitalise on the expertise and multidisciplinary collaborations of several groups, all leaders in their fields, and whose collective track record in clinical nutrition research cannot be matched in Australia, to form a Centre of ....Over 20% of Australian adults either have diabetes, or are at imminent risk, while 60% are overweight or obese. Conversely, some 40% of the elderly receiving domiciliary support are at risk of malnutrition. Poor nutrition underpins numerous chronic diseases. We seek to capitalise on the expertise and multidisciplinary collaborations of several groups, all leaders in their fields, and whose collective track record in clinical nutrition research cannot be matched in Australia, to form a Centre of Excellence that encompasses the physiology of nutrition, dietary intervention strategies, and evaluation of outcomes, in diabetic, overweight, elderly, and critically unwell populations.Read moreRead less
Centre Of Clinical Research Excellence In Aboriginal Health
Funder
National Health and Medical Research Council
Funding Amount
$1,899,510.00
Summary
The Centre's mission is to improve Aboriginal health. It will conduct Aboriginal community-controlled population health and outcome-oriented research on strategies and systems that support individuals and communities to prevent and manage chronic diseases. The Centre will provide a range of research and other training opportunities for Aboriginal people, building the capacity of Aboriginal communities to direct and conduct their own health research independently. The Centre will be led by the Ab ....The Centre's mission is to improve Aboriginal health. It will conduct Aboriginal community-controlled population health and outcome-oriented research on strategies and systems that support individuals and communities to prevent and manage chronic diseases. The Centre will provide a range of research and other training opportunities for Aboriginal people, building the capacity of Aboriginal communities to direct and conduct their own health research independently. The Centre will be led by the Aboriginal Health Council of South Australia in partnership with Flinders University.Read moreRead less
This national research centre uniquely combines two recent advances in rehabilitation, applies them to rehabilitation of acquired communication disorder (aphasia) and translates them into a clear pathway for clinical management of people with aphasia. This cell to society research program integrates a consumer's perspective into research in the relearning of lost skills after injury. The resulting Australian Aphasia Clinical Pathway will enable and ensure best practice in aphasia services.
Centre For Clinical Research Excellence To Improve Outcomes In Chronic Liver Disease
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
This Centre will provide new information to improve clinical outcomes for people with chronic liver disease. Among people referred by GPs with abnormal liver tests, two thirds have hepatitis C or non-alcoholic steatohepatitis. The Centre aims to develop non-invasive ways to identify those with progressive liver disease, and will assess whether lifestyle adjustments (diet and exercise) improve liver injury and fibrosis progression. They hope to improve the health and survival of people with advan ....This Centre will provide new information to improve clinical outcomes for people with chronic liver disease. Among people referred by GPs with abnormal liver tests, two thirds have hepatitis C or non-alcoholic steatohepatitis. The Centre aims to develop non-invasive ways to identify those with progressive liver disease, and will assess whether lifestyle adjustments (diet and exercise) improve liver injury and fibrosis progression. They hope to improve the health and survival of people with advanced stage cirrhosis who are waiting for a liver transplant by correcting nutritional problems, osteoporosis and earlier detection and treatment of liver cancer. The program forms the basis for clinical research training for GPs, specialists, nurses, dieticians, sports medicine and other health care professionals.Read moreRead less