The Australian Proteomics Computational Facility (APCF)
Funder
National Health and Medical Research Council
Funding Amount
$2,509,000.00
Summary
In recent years, Australia has invested in the equipment capable of identifying proteins important in health and medicine. This sophisticated equipment requires high capacity computing support. The Australian Proteomics Computational Facility will establish a single advanced computing cluster accessible to scientists at proteomics centres all over the country. This integrated approach to proteomics computing and the sharing of databases will put Australia at the forefront of the world�s efforts ....In recent years, Australia has invested in the equipment capable of identifying proteins important in health and medicine. This sophisticated equipment requires high capacity computing support. The Australian Proteomics Computational Facility will establish a single advanced computing cluster accessible to scientists at proteomics centres all over the country. This integrated approach to proteomics computing and the sharing of databases will put Australia at the forefront of the world�s efforts to identify the proteins associated with the early detection of our major diseasesRead moreRead less
National Non-human Primate Breeding And Research Facility
Funder
National Health and Medical Research Council
Funding Amount
$2,640,742.00
Summary
Some biomedical research is best undertaken on primates, in order to allow the greatest relevance to understanding health and disease in humans. Examples of such research include studies into diseases like HIV-AIDS and much of the research into understanding the human brain and nervous system. The National Health and Medical Research Committee (NHMRC), through its Animal Welfare Committee, has taken an international leadership position in ensuring that any non-human primates used for biomedical ....Some biomedical research is best undertaken on primates, in order to allow the greatest relevance to understanding health and disease in humans. Examples of such research include studies into diseases like HIV-AIDS and much of the research into understanding the human brain and nervous system. The National Health and Medical Research Committee (NHMRC), through its Animal Welfare Committee, has taken an international leadership position in ensuring that any non-human primates used for biomedical research are bred and housed in the best possible facilities and looked after with the highest level of care available. To ensure this quality of care, it is NHMRC policy to only use animals that have been bred and reared specifically for research purposes. The National Non-Human Primate Breeding and Research Facility, hosted by Monash University, ensures that Australian community has access to macaque monkeys and marmosets to carry out research under the highest quality conditions. Additionally the colonies will provide a key resource in any national response to pandemics and bioterrorism for vaccine and response development.Read moreRead less
Protocol Development, Web-based Data Collection And Data Quality For All Cancer Cooperative Trials Groups
Funder
National Health and Medical Research Council
Funding Amount
$1,840,000.00
Summary
Each year, 85,000 Australian develop cancer and 35,000 die of it. The Clinical Oncological Society of Australia and nine Australian cancer trials groups run studies that test new and better ways of preventing, curing, treating and palliating people affected by cancer. This grant will help these groups start trials faster; run them more efficiently; coordinate quality assurance; and standardize operating procedures. This grant will enable collaboration that increases the speed, efficiency and qua ....Each year, 85,000 Australian develop cancer and 35,000 die of it. The Clinical Oncological Society of Australia and nine Australian cancer trials groups run studies that test new and better ways of preventing, curing, treating and palliating people affected by cancer. This grant will help these groups start trials faster; run them more efficiently; coordinate quality assurance; and standardize operating procedures. This grant will enable collaboration that increases the speed, efficiency and quality of cancer research to lessen the suffering of people affected by cancer.Read moreRead less
Australasian Leukaemia Lymphoma Group (ALLG) National Leukaemia And Lymphoma Tissue Bank (NLLTB)
Funder
National Health and Medical Research Council
Funding Amount
$2,106,750.00
Summary
Recent advances in knowledge about how cancer differ from normal cells, why some people are susceptible to cancer, and how new treatments can target cancer have all occurred through research on cancer cells from patients. To benefit patients with cancers of the blood and the immune system, we established a National Leukaemia and Lymphoma Tissue Bank in 2002. It is proposed to dramatically expand its size, add relevant clinical data, and streamline access and utility for Australian researchers. U ....Recent advances in knowledge about how cancer differ from normal cells, why some people are susceptible to cancer, and how new treatments can target cancer have all occurred through research on cancer cells from patients. To benefit patients with cancers of the blood and the immune system, we established a National Leukaemia and Lymphoma Tissue Bank in 2002. It is proposed to dramatically expand its size, add relevant clinical data, and streamline access and utility for Australian researchers. Ultimately, this will lead to better treatment and prevention of blood cancers.Read moreRead less
Australian Paediatrics Surveillance Unit: A Collaborative Network For Child Health Research
Funder
National Health and Medical Research Council
Funding Amount
$1,254,500.00
Summary
The proposed Facility will formalise a collaborative, national network of organisations to enable the conduct and dissemination of research on serious child health conditions. The Facility will provide a reliable, accessible, unique mechanism for national research that is aligned with national priorities and addresses knowledge gaps. It will disseminate that research widely to inform clinical practice, policy, prevention programs, resource allocation, the community and health professionals.
Australian Centre For Vertebrate Mutation Detection (ACVMD)
Funder
National Health and Medical Research Council
Funding Amount
$1,611,794.00
Summary
Over the last 20 years, generation and analysis of genetically modified animals has proven to be an important step in the transition from in vitro studies of gene function to in vivo studies and eventually clinical research. The remarkable parallels between the human, mouse and zebrafish genomes means that there are now many examples of mutations that cause or modify disease in humans, and which lead to similar phenotypes when present in mice and zebrafish. Until recently, the prime method of in ....Over the last 20 years, generation and analysis of genetically modified animals has proven to be an important step in the transition from in vitro studies of gene function to in vivo studies and eventually clinical research. The remarkable parallels between the human, mouse and zebrafish genomes means that there are now many examples of mutations that cause or modify disease in humans, and which lead to similar phenotypes when present in mice and zebrafish. Until recently, the prime method of introducing mutations into specific genes of interest in the mouse (although still unavailable in the fish) was via homologous recombination, and the principal classes of mutations induced were large deletions or insertions. This type of mutation rarely occurs in humans. Rather, point mutations and single-nucleotide polymorphisms are the prevalent form of genetic variation. An alternative approach to the development of mouse models with the more relevant point mutations is TILLING (Targeting Induced Local Lesions IN Genomes). The goal of this Enabling Grant is to make TILLING technology accessible to the Australian research community and in doing so promote movement of research from the in vitro setting into animal models of disease.Read moreRead less