Prospective Imaging Study Of Ageing: Genes, Brain & Behaviour
Funder
National Health and Medical Research Council
Funding Amount
$6,465,047.00
Summary
While the burden of dementia in Australia occurs late in life, the underlying brain disease accumulates for decades prior to dementia onset. Disease modifying interventions have the greatest potential to avert later disease burden if introduced during this crucial window, well before the onset of clear cognitive decline. To reduce Australia's future dementia burden, it is thus imperative to identify those Australians at risk of dementia whilst they are still relatively young.
Mental illnesses are the largest single cause of disability and costs the economy $56.7 billion per year. Depression and anxiety in those with dementia lead to poorer outcomes with reduced quality of life, poor functional status and worsening cognition, despite under-treatment. I will develop an integrated network in Australia to maximise treatment outcomes for depression and anxiety in dementia.