Discovery Early Career Researcher Award - Grant ID: DE150100652
Funder
Australian Research Council
Funding Amount
$345,000.00
Summary
Regulation of organ size and stem cell hierarchy in the developing kidney. Transient stem/progenitor cell populations play essential roles in establishing organ systems. The balance between self-renewal and differentiation in the nephron progenitor population plays a major, but poorly understood, role in regulating kidney development. Factors produced by undifferentiated progenitors promote organ expansion, whereas differentiation of these cells builds functional capacity. What is not clear is h ....Regulation of organ size and stem cell hierarchy in the developing kidney. Transient stem/progenitor cell populations play essential roles in establishing organ systems. The balance between self-renewal and differentiation in the nephron progenitor population plays a major, but poorly understood, role in regulating kidney development. Factors produced by undifferentiated progenitors promote organ expansion, whereas differentiation of these cells builds functional capacity. What is not clear is how the balance between self-renewal and differentiation is regulated in these cells, nor how the control of this fate decision impacts on optimal organ development. This project aims to dissect the molecular identity, regulation, and influence of this stem cell population on kidney development.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100377
Funder
Australian Research Council
Funding Amount
$317,185.00
Summary
Women and the rise of contact sport. This project aims to investigate the growing visibility of women in contact sports in Australia and the multiple forces that influence their participation. Expected outcomes of this project include the enhanced capacity of contact sports to include and support women's participation; it does this by engaging with policies and practices that work towards gender equality and long-term sustainability.
Discovery Early Career Researcher Award - Grant ID: DE140100569
Funder
Australian Research Council
Funding Amount
$372,952.00
Summary
Recovering helium from Australia’s natural gas: A case study for advanced adsorption processes to concentrate dilute gases. This project will deliver breakthroughs in gas separation technologies for the production of helium from natural gas. Global demand for helium in critical medical, scientific and industrial applications is projected to grow at around five per cent per annum. To overcome the forecast short falls in helium production, new low cost and energy efficient technologies to recover ....Recovering helium from Australia’s natural gas: A case study for advanced adsorption processes to concentrate dilute gases. This project will deliver breakthroughs in gas separation technologies for the production of helium from natural gas. Global demand for helium in critical medical, scientific and industrial applications is projected to grow at around five per cent per annum. To overcome the forecast short falls in helium production, new low cost and energy efficient technologies to recover helium from natural gas fields must be developed. This project will contribute novel microporous adsorbents, a better understanding of helium sorption kinetics and general methodologies for design of pressure swing adsorption processes to concentrate dilute mixtures.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100524
Funder
Australian Research Council
Funding Amount
$365,057.00
Summary
Manipulating selected inflammatory responses in macrophages. This project aims to define the structural and functional interactions of a new transmembrane adaptor SCIMP. SCIMP has recently been shown to effect the inflammatory pathway. The project outcomes will include the first structure of this unconventional complex. The project will have significant flow on benefits including new knowledge and new protein methodologies for end-users in research and industry, and ultimately economic impact.
Discovery Early Career Researcher Award - Grant ID: DE240101170
Funder
Australian Research Council
Funding Amount
$458,237.00
Summary
Design new-generation microscale thermoelectric device. This project aims at realizing ultrahigh thermoelectric power generating performance in the microscale device by developing new theoretical models for thermoelectric power-generation to guide the synergistic thin-film material and device design, and corresponding fabrication. The outcomes are expected to lead to revolutionary development of the thermoelectric technology, significantly extend the application of this emission/vibration/noise/ ....Design new-generation microscale thermoelectric device. This project aims at realizing ultrahigh thermoelectric power generating performance in the microscale device by developing new theoretical models for thermoelectric power-generation to guide the synergistic thin-film material and device design, and corresponding fabrication. The outcomes are expected to lead to revolutionary development of the thermoelectric technology, significantly extend the application of this emission/vibration/noise/service-free technology and expand the corresponding market, which will benefit the wide Australian community academically, educationally, socially, economically and environmentally.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100585
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Does foot shape even matter? Rethinking the function of the human foot. Human feet are unique in shape and structure, having evolved to allow upright locomotion. Despite their importance, we don’t understand how foot shape and structure facilitates upright locomotion.This DECRA aims to explore the relationship between foot morphology and foot function. I will close a large knowledge gap by applying novel experimental and shape modelling approaches to provide unprecedented insights into human foo ....Does foot shape even matter? Rethinking the function of the human foot. Human feet are unique in shape and structure, having evolved to allow upright locomotion. Despite their importance, we don’t understand how foot shape and structure facilitates upright locomotion.This DECRA aims to explore the relationship between foot morphology and foot function. I will close a large knowledge gap by applying novel experimental and shape modelling approaches to provide unprecedented insights into human foot function. The primary expected outcome is a detailed understanding of how foot shape and structure influences our ability to walk and run. This research will create a paradigm shift in how we think about feet in the context of human evolution, human athletic performance and athletic footwear design.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100490
Funder
Australian Research Council
Funding Amount
$426,742.00
Summary
Understanding infection tolerance to improve management of wildlife disease. This project aims to investigate tolerance (the ability to limit the detrimental effects of infection) as a key animal defence strategy against disease. It focuses on diseases in natural systems, using the devastating amphibian fungal skin disease, chytridiomycosis, as a model. Expected outcomes include improved understanding of the relative importance of tolerance and resistance, and insight into the key immune and phy ....Understanding infection tolerance to improve management of wildlife disease. This project aims to investigate tolerance (the ability to limit the detrimental effects of infection) as a key animal defence strategy against disease. It focuses on diseases in natural systems, using the devastating amphibian fungal skin disease, chytridiomycosis, as a model. Expected outcomes include improved understanding of the relative importance of tolerance and resistance, and insight into the key immune and physiologic mechanisms underlying variations in tolerance. Anticipated benefits include improved strategies for mitigating infectious wildlife diseases via identifying targets for therapeutic interventions, ecological management and assisted-evolution strategies. This project should also benefit amphibian conservation globally.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120100995
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Visual navigation for sunny summer days and stormy winter nights. This project will develop innovative techniques for camera-based navigation that recognise locations under a wide range of environmental conditions caused by day-night cycles, weather and seasonal change. These techniques will enable the widespread use of cheap and lightweight cameras in robot and personal navigation systems.
Discovery Early Career Researcher Award - Grant ID: DE240100611
Funder
Australian Research Council
Funding Amount
$393,664.00
Summary
Building community resilience to coastal climate hazards in Australia. More frequent and intense climate hazards are devastating Australian communities and are projected to worsen as climate changes. This project aims to develop and communicate urgently needed strategies to assist coastal communities to prepare for and respond to climate hazards. The relationship between local-scale connection and capacity to prepare and respond will be investigated using mixed methods research in at-risk commun ....Building community resilience to coastal climate hazards in Australia. More frequent and intense climate hazards are devastating Australian communities and are projected to worsen as climate changes. This project aims to develop and communicate urgently needed strategies to assist coastal communities to prepare for and respond to climate hazards. The relationship between local-scale connection and capacity to prepare and respond will be investigated using mixed methods research in at-risk communities. The research will deliver practical guidance to policy makers and managers that will optimise investments in building community resilience, advance the discipline of human geography, and benefit over 20 million Australians living in coastal areas by creating new knowledge on neighbourhood adaptive capacity.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101523
Funder
Australian Research Council
Funding Amount
$308,747.00
Summary
Enterprising Chinese Australians and the diaspora networks, 1890-1949. From the late 19th century to the present, Chinese Australian businesses and merchants have played an important but under-acknowledged role in bilateral trade and investment. This project aims to provide the first systematic study of how Chinese Australian enterprises and diasporic networks were developed from the late 19th to the early 20th century. Historical insights will be enhanced through extensive use of bilingual arch ....Enterprising Chinese Australians and the diaspora networks, 1890-1949. From the late 19th century to the present, Chinese Australian businesses and merchants have played an important but under-acknowledged role in bilateral trade and investment. This project aims to provide the first systematic study of how Chinese Australian enterprises and diasporic networks were developed from the late 19th to the early 20th century. Historical insights will be enhanced through extensive use of bilingual archival sources. The proposition to be explored is that Chinese business culture in diaspora was not simply oriented to economic survival and money-making, it was also an important element of building a trans-local community with diasporic aspects in everyday life.Read moreRead less