Industrial Transformation Training Centres - Grant ID: IC180100024
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, internatio ....ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, international collaborations and a generation of industry-ready researchers critical for growing Australia’s industry. The advances in materials and savings in time for procedures will reduce costs.
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Identifying components of a novel imprinting mechanism that regulates seed size in plants. Australia is a major exporter of agricultural food crops thus producers must maintain their competitive advantage in order to compete on the world stage. This project will study a fundamental biological process of seed development as seeds are a major food staple and an important export product for Australian farmers.
A nanoengineered solution to drug delivery in bone. This project presents an exciting new approach of applying nanotechnology to bone research. By combining our expertise in nanoengineering of new materials, mathematical modelling and bone biology, this project will result in a well-characterised model for drug delivery into bone and lead to a new therapeutic approach for treating bone diseases.
Industrial Transformation Training Centres - Grant ID: IC190100020
Funder
Australian Research Council
Funding Amount
$3,998,796.00
Summary
ARC Industrial Transformation Training Centre for Joint Biomechanics. The Centre aims to bring together leading researchers, industry partners and end-users to train a new generation of interdisciplinary and skilled graduates to tackle industry-focused challenges in joint biomechanics. The centre will provide advances required to transform personalised surgical treatment of joints through integrated technologies of computer tools for pre-surgical planning and decision making, the computer simula ....ARC Industrial Transformation Training Centre for Joint Biomechanics. The Centre aims to bring together leading researchers, industry partners and end-users to train a new generation of interdisciplinary and skilled graduates to tackle industry-focused challenges in joint biomechanics. The centre will provide advances required to transform personalised surgical treatment of joints through integrated technologies of computer tools for pre-surgical planning and decision making, the computer simulation system and robot simulators for surgical training and medical device assessment, and post-surgical assessment tools. The outcomes of the centre will significantly contribute to Australia by improved health outcomes, economic benefits, and a skilled workforce able to advance this joint biomechanics fields.Read moreRead less
ARC Centre of Excellence for Mathematical and Statistical Frontiers of Big Data, Big Models, New Insights. In today's world, massive amounts of data in a variety of forms are collected daily from a multitude of sources. Many of the resulting data sets have the potential to make vital contributions to society, business and government, as well as impact on international developments, but are so large or complex that they are difficult to process and analyse using traditional tools. The aim of this ....ARC Centre of Excellence for Mathematical and Statistical Frontiers of Big Data, Big Models, New Insights. In today's world, massive amounts of data in a variety of forms are collected daily from a multitude of sources. Many of the resulting data sets have the potential to make vital contributions to society, business and government, as well as impact on international developments, but are so large or complex that they are difficult to process and analyse using traditional tools. The aim of this Centre is to create innovative mathematical and statistical models that can uncover the knowledge concealed within the size and complexity of these big data sets, with a focus on using the models to deliver insight into problems vital to the Centre's Collaborative Domains: Healthy People, Sustainable Environments and Prosperous Societies.Read moreRead less
The genetic regulation of organogenesis: endoderm development in the Drosophila embryo. Embryonic development is an important research field in biology, not only for its extraordinary complexity but also because of the insights it provides into molecular processes that underpin a variety of diseases. This project aims to discover genes and molecules that regulate the normal development of one of the most important organs, the gut.
Interactions between cells and extracellular matrix in the epithelial-mesenchymal transition of the ovarian follicular stratified epithelium. The lining of many mammalian organs and cavities contain cells that can transform into different cells to bring about organ development or repair but if it goes horribly wrong the cells become metastatic cancers. This project examines the key features of this process especially the roles of matrix that develops around the cells in this process.
Industrial Transformation Training Centres - Grant ID: IC210100019
Funder
Australian Research Council
Funding Amount
$4,583,816.00
Summary
ARC Training Centre for Optimal Ageing. The ARC Training Centre for Optimal Ageing aims to address issues identified by older adults as essential for quality of life. With our industry partners, we aim to train the next generation of researchers to understand, detect and improve psychosocial factors that support mental activity, physical health and social connectedness, and embrace advances in artificial intelligence, digital-enriched environments and adaptive workplaces to deliver effective dig ....ARC Training Centre for Optimal Ageing. The ARC Training Centre for Optimal Ageing aims to address issues identified by older adults as essential for quality of life. With our industry partners, we aim to train the next generation of researchers to understand, detect and improve psychosocial factors that support mental activity, physical health and social connectedness, and embrace advances in artificial intelligence, digital-enriched environments and adaptive workplaces to deliver effective digital solutions. By developing new capacity and capability to drive the digital transformation of industries supporting our ageing population, our Centre seeks to deliver economic and social benefits that enable Australians to live enriched, healthy and independent lives as they age.Read moreRead less
Pushing the Boundaries of Multi-modal Biospectroscopic Microscopies. In order to understand the fundamentals of life processes, diseases, and their treatments, it is essential to probe fundamental changes in molecular processes in cells, tissues and whole organisms. Much of our understanding of these processes has involved the introduction of chemical probes for biospectroscopy, but these have inherent problems because the probe can often change the biochemistry that is being probed. This projec ....Pushing the Boundaries of Multi-modal Biospectroscopic Microscopies. In order to understand the fundamentals of life processes, diseases, and their treatments, it is essential to probe fundamental changes in molecular processes in cells, tissues and whole organisms. Much of our understanding of these processes has involved the introduction of chemical probes for biospectroscopy, but these have inherent problems because the probe can often change the biochemistry that is being probed. This project will push the boundaries of a variety of micro and nano "probe-free" microscopies to provide fundamental insights into these life processes, which could ultimately lead to improvements in the diagnosis, prevention and treatment of diseases.Read moreRead less
Surface Engineered Biomaterials to Control Inflammation. The overarching aim of this project is to provide a mechanistic understanding of how surface nanotopography affects inflammatory responses. Experimental evidence demonstrates that engineered surface nanotopography in combination with surface chemistry downregulates the expression of proinflammatory cytokines from primary macrophages. The significance of these findings is that it may be possible to engineer the nanotopography of a biomedica ....Surface Engineered Biomaterials to Control Inflammation. The overarching aim of this project is to provide a mechanistic understanding of how surface nanotopography affects inflammatory responses. Experimental evidence demonstrates that engineered surface nanotopography in combination with surface chemistry downregulates the expression of proinflammatory cytokines from primary macrophages. The significance of these findings is that it may be possible to engineer the nanotopography of a biomedical device surface in a manner which leads to a desired and predictable level of inflammation and subsequent foreign body reaction (FBR) medical implants and tissue engineering constructs.Read moreRead less