Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100158
Funder
Australian Research Council
Funding Amount
$470,000.00
Summary
Small angle X-ray scattering facility for Queensland. This project aims to provide an advanced small angle X-ray scattering facility for the examination of versatile porous and nano-size sample types. Understanding the structure-function relationship is crucial for developing high-performance nanostructured materials in bio-applications, renewable energy, energy storage, and water treatment. The proposed facility will support the development of new functional materials for industry reform, mappi ....Small angle X-ray scattering facility for Queensland. This project aims to provide an advanced small angle X-ray scattering facility for the examination of versatile porous and nano-size sample types. Understanding the structure-function relationship is crucial for developing high-performance nanostructured materials in bio-applications, renewable energy, energy storage, and water treatment. The proposed facility will support the development of new functional materials for industry reform, mapping oil and gas reserves, developing innovative technologies for new energy resources, and gas deliverability. The project is strongly aligned with the Advanced Manufacturing Science and Research Priority by providing high-performance materials, and generating new technologies to support major industries in Queensland and Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100179
Funder
Australian Research Council
Funding Amount
$3,189,000.00
Summary
Automated high resolution and high contrast cryo -TEM for three-dimensional structural biology. This project aims to establish a facility in automated, single-particle cryo-TEM and cryo-TEM tomography (Titan Krios) that will enable atomic and molecular structure research and three-dimensional subcellular and cellular imaging. The project will span all multiscale cryo-TEM modalities from the visualisation of cells, membranes and macromolecular complexes, through to near-atomic-resolution protein ....Automated high resolution and high contrast cryo -TEM for three-dimensional structural biology. This project aims to establish a facility in automated, single-particle cryo-TEM and cryo-TEM tomography (Titan Krios) that will enable atomic and molecular structure research and three-dimensional subcellular and cellular imaging. The project will span all multiscale cryo-TEM modalities from the visualisation of cells, membranes and macromolecular complexes, through to near-atomic-resolution protein structure determination. Cryo-single particle analysis and tomography are recognised as revolutionary technologies in molecular structural biology and powerful enablers of future ground-breaking discovery. The project will deliver significant competitive advantage for Australia in leading-edge structure-based research, drug discovery, new opportunities for applied research and development, and showcasing science to the public.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100192
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
Deep Protein Sequencing, Structure and Quantification Facility. This project aims to establish state-of-the-art complementary mass spectrometers to help research into molecular structure and interactions, post-translational modifications, compound stability and availability within complex biological samples. The facility’s complementary mass spectrometers combine high specificity with high sensitivity and ultrafast scanning, and are expected to rapidly discover, identify and characterise biomole ....Deep Protein Sequencing, Structure and Quantification Facility. This project aims to establish state-of-the-art complementary mass spectrometers to help research into molecular structure and interactions, post-translational modifications, compound stability and availability within complex biological samples. The facility’s complementary mass spectrometers combine high specificity with high sensitivity and ultrafast scanning, and are expected to rapidly discover, identify and characterise biomolecules including peptides, proteins and small molecules. The discovery of unknown compounds is expected to improve fundamental understanding of molecular structure and function, provide opportunities for new bio-industries in health and the environment, and generate commercial opportunities through spin-off companies, patents and licensing.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100093
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Shared laser facility. This shared laser facility will provide a pool of lasers to support the research of about 20 research groups and 30 PhD students.
Accessing the therapeutic potential of carbon monoxide. Despite carbon monoxide being regarded as the ”silent killer”, it is now established that this molecule has beneficial effects for a number of conditions and pathologies, including inflammation, organ transplant rejection, bacterial infection, acute liver failure and as an aid in cancer therapies. This project proposes to explore the photochemistry of rhenium-containing species to discover more efficient carbon monoxide delivery agents. By ....Accessing the therapeutic potential of carbon monoxide. Despite carbon monoxide being regarded as the ”silent killer”, it is now established that this molecule has beneficial effects for a number of conditions and pathologies, including inflammation, organ transplant rejection, bacterial infection, acute liver failure and as an aid in cancer therapies. This project proposes to explore the photochemistry of rhenium-containing species to discover more efficient carbon monoxide delivery agents. By combining synthetic chemistry, photochemistry and cellular biology it is anticipated that this multidisciplinary research programme will advance the area of carbon monoxide therapies by preparing safer agents for the targeted and controlled delivery of carbon monoxide.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100059
Funder
Australian Research Council
Funding Amount
$220,000.00
Summary
Multiplexed capabilities for surface analysis and imaging by mass spectrometry. This facility will support research aimed at developing rapid and reliable analytical methods for the detection of chemicals directly from biological and man-made materials. The mass spectroscopy methods used at the facility will reveal molecular-level changes in systems ranging from the lens of the human eye to Colorbond steel® and have applications in the detection of chemical and biological hazards.
Discovery Early Career Researcher Award - Grant ID: DE120101456
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Electrochemical behaviour of toxic gases and explosives in room temperature ionic liquids. This project will examine the behaviour of toxic gases and volatile explosive materials in ionic liquids. The information generated from this work will provide fundamental knowledge that will allow for the design of improved sensors for toxic gases, nerve agents and explosives, for applications in the mining and security sectors.
Vortex fluidic mediated chemical transformations. This project aims to develop a continuous flow vortex fluidic device (VFD) for chemical and biochemical transformations. Vortex fluidic devices should lead to cleaner and faster ways of preparing complex molecules. Depending on the VFD’s operating parameters, including applying field effects such as Faraday waves, plasmas and light sources, reactions could have higher yields and selectivity than traditional batch processing. This will be translat ....Vortex fluidic mediated chemical transformations. This project aims to develop a continuous flow vortex fluidic device (VFD) for chemical and biochemical transformations. Vortex fluidic devices should lead to cleaner and faster ways of preparing complex molecules. Depending on the VFD’s operating parameters, including applying field effects such as Faraday waves, plasmas and light sources, reactions could have higher yields and selectivity than traditional batch processing. This will be translated into molecular assembly line syntheses in a single unit or a series. Such syntheses should provide a versatile toolbox for molecular transformations, under continuous flow conditions where scalability is addressed upfront. This will be attractive to industry and minimise effects on the environment.Read moreRead less
Sulphate sensor for reverse osmosis integrity and performance monitoring. Sulphate sensor for reverse osmosis integrity and performance monitoring. This project aims to investigate new chemical sensors for sulphate for online reverse osmosis integrity and performance monitoring at an advanced water recycling plant. Wastewater re-use is increasingly important in Australia and worldwide for providing potable water. Demonstrating the integrity and performance of treatment technologies is needed to ....Sulphate sensor for reverse osmosis integrity and performance monitoring. Sulphate sensor for reverse osmosis integrity and performance monitoring. This project aims to investigate new chemical sensors for sulphate for online reverse osmosis integrity and performance monitoring at an advanced water recycling plant. Wastewater re-use is increasingly important in Australia and worldwide for providing potable water. Demonstrating the integrity and performance of treatment technologies is needed to meet health regulations. Sulphate and other surrogates of biological entities enable a rapid, on-line approach to integrity and performance monitoring, but detection with available analytical chemical technology is not feasible. This research is expected to enable better management of water treatment processes and demonstrate compliance to health standards.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100024
Funder
Australian Research Council
Funding Amount
$520,000.00
Summary
Melbourne and Monash integrated proteomics facility. This project will provide two Victorian proteomic core facilities with cutting edge technology that will address a major gap in our mass spectrometry and protein interaction capabilitiy. These core facilities support a vast array of basic/applied research that depends on the characterisation of proteins and small molecules at a molecular level.