Multifunctional biodegradable nanoparticles for enhanced DNA vaccine delivery. DNA vaccine, which shows better immunological and economic merits than conventional vaccines, suffers clinical failure due to the difficulty of delivering intact DNA molecules to relevant cells. This project seeks to develop smart polymer nanospheres to protect the DNA molecules from premature degradation in order to improve its efficacy.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100125
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
Advanced fluorescence imaging facility: from super high resolution to whole animal imaging. The establishment of this advanced fluorescence imaging facility will provide cutting-edge infrastructure to examine cells, pathogens and interactions between engineered drug delivery systems in both cells and whole animals. The facility will foster the development of new nanomedicines.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100100
Funder
Australian Research Council
Funding Amount
$440,000.00
Summary
Cytometer by Time of Flight (CyTOF): A New Paradigm in Cytometry. Cytometer by Time of Flight (CyTOF) - a new paradigm in cytometry: The acquisition of a Cytometer by Time of Flight will allow multiparametric characterisation of biological systems and quantitative analysis of nano-bio interactions at the single cell level. The convergence of nanotechnology with biomedicine offers unprecedented opportunities for biological applications, including targeted therapeutics. One of the major challenges ....Cytometer by Time of Flight (CyTOF): A New Paradigm in Cytometry. Cytometer by Time of Flight (CyTOF) - a new paradigm in cytometry: The acquisition of a Cytometer by Time of Flight will allow multiparametric characterisation of biological systems and quantitative analysis of nano-bio interactions at the single cell level. The convergence of nanotechnology with biomedicine offers unprecedented opportunities for biological applications, including targeted therapeutics. One of the major challenges lies in understanding the complex interactions between nanoengineered materials and biological systems.Read moreRead less