Tectonic evolution and lode gold mineralisation in the Southern Cross district, Yilgarn Craton (Western Australia): a study of the meso- to Neoarchaean missing link. In the December quarter 2008, Gold export earnings increased by 2 per cent to $3.9 billion. Over the past 20 years and despite an increase in exploration expenditure to around $50 million per year, the discovery rates have been declining. Although the easy targets have been found, there remains considerable potential for future ma ....Tectonic evolution and lode gold mineralisation in the Southern Cross district, Yilgarn Craton (Western Australia): a study of the meso- to Neoarchaean missing link. In the December quarter 2008, Gold export earnings increased by 2 per cent to $3.9 billion. Over the past 20 years and despite an increase in exploration expenditure to around $50 million per year, the discovery rates have been declining. Although the easy targets have been found, there remains considerable potential for future major discoveries. This project addresses the pressing need for new data and improved exploration techniques to enable industry to target new discoveries. As the Southern Cross district is located in remote communities such discoveries also have major benefits for regional Australia.Read moreRead less
Devices that use Ion Channels. The proposed device would supply the community of researchers in Australia and internationally with new techniques to enable them to quickly and conveniently investigate properties of ion channels and to speed the screening of potential ion channel targets for pharmaceutical hits and leads. In addition, the tethered membrane technology will be developed to fill an unmet need for a quick and biologically relevant test of EMC hazards. This will enhance the science an ....Devices that use Ion Channels. The proposed device would supply the community of researchers in Australia and internationally with new techniques to enable them to quickly and conveniently investigate properties of ion channels and to speed the screening of potential ion channel targets for pharmaceutical hits and leads. In addition, the tethered membrane technology will be developed to fill an unmet need for a quick and biologically relevant test of EMC hazards. This will enhance the science and technology infrastructure within Australia, taking it into original and exciting directions, contribute to training young Australian scientists and students, as well as enhance Australia's competitive position in the field of nanobiotechnology.Read moreRead less
Wheat biomarkers - the effect of nitrogen withdrawal on the proteome and peptidome. Nitrogen is a crucial macroelement for plants. Its importance is highlighted by the wide use of agricultural nitrogen fertilizers in Australia and world wide. This comes at substantial costs for the environment and the economy, due to low nitrogen use efficiency of cereals and environmental impacts. By understanding plant responses to nitrogen we can improve nitrogen efficiency. This project will identify protein ....Wheat biomarkers - the effect of nitrogen withdrawal on the proteome and peptidome. Nitrogen is a crucial macroelement for plants. Its importance is highlighted by the wide use of agricultural nitrogen fertilizers in Australia and world wide. This comes at substantial costs for the environment and the economy, due to low nitrogen use efficiency of cereals and environmental impacts. By understanding plant responses to nitrogen we can improve nitrogen efficiency. This project will identify proteins and peptides as biomarkers of plant responses to nitrogen withdrawal. Such biomarkers can be used in plant breeding and in agricultural prediction of plant nitrogen requirements with the potential to reduce agricultural costs and environmental impacts.Read moreRead less
Bacterial Proteomics: From Cell Division to Novel Antibiotic Targets. When a cell divides it is essential that each newborn cell gets a complete copy of the DNA. To ensure that this happens, cell division must be tightly controlled. It is not known how this occurs in bacteria. However, if we knew what molecules were involved in this control, we could target them to kill harmful bacteria. This project aims to identify such regulatory molecules as candidate targets for antimicrobial agents, with a ....Bacterial Proteomics: From Cell Division to Novel Antibiotic Targets. When a cell divides it is essential that each newborn cell gets a complete copy of the DNA. To ensure that this happens, cell division must be tightly controlled. It is not known how this occurs in bacteria. However, if we knew what molecules were involved in this control, we could target them to kill harmful bacteria. This project aims to identify such regulatory molecules as candidate targets for antimicrobial agents, with a view to developing powerful, novel antibiotics to protect us from the imminent threat of bioterrorism and antibiotic-resistant bacteria.
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Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices. This project aims to characterise the interaction of transport proteins with unsupported lipid bilayer membranes. This will provide the basis for a novel biosensor utilising mechanosensitive ion channels incorporated into an artificial lipid bilayer membrane. To support this outcome, the project will develop the planar patch-clamp electrophysiology recording techniques suitable for l ....Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices. This project aims to characterise the interaction of transport proteins with unsupported lipid bilayer membranes. This will provide the basis for a novel biosensor utilising mechanosensitive ion channels incorporated into an artificial lipid bilayer membrane. To support this outcome, the project will develop the planar patch-clamp electrophysiology recording techniques suitable for liposomes. This provides a significant PhD training opportunity and brings an international focus to the development of planar patch-clamp electrophysiology in Australia. The project has significant commercial potential by developing both the planar patch-clamp electrophysiology techniques for liposomes and producing a novel biomimetic mechanosensitive biosensor.Read moreRead less
Tertiary education and social capital in Victoria: the effects of the new economy courses in Business and IT. Over one third of tertiary students are enrolled in the fast-growing new economy disciplines in business studies and IT. In partnership with the Victorian government, this project studies the contribution of business and IT courses to social capital, the collaborative networks that underpin economic innovation and sustainable community. The research will survey and interview Victorian 15 ....Tertiary education and social capital in Victoria: the effects of the new economy courses in Business and IT. Over one third of tertiary students are enrolled in the fast-growing new economy disciplines in business studies and IT. In partnership with the Victorian government, this project studies the contribution of business and IT courses to social capital, the collaborative networks that underpin economic innovation and sustainable community. The research will survey and interview Victorian 1500 graduates from 12 higher education and VET institutions (6 rural); and survey and interview employers and community leaders. The research will inform Victoria's education policy and Growing Victoria Together strategy, and encourage tertiary institutions throughout Australia to strengthen their contribution to social capital.Read moreRead less
Improving university teaching: Creating strategies and tools to support the design process. This project will create strategies and tools to help university teachers design effective online learning experiences. Excellence in online education is important to Australia, socially and economically. Social benefits come from greater participation and graduates better equipped to contribute to their communities. Economic benefits come from graduates with skills and knowledge to be flexible, adaptable ....Improving university teaching: Creating strategies and tools to support the design process. This project will create strategies and tools to help university teachers design effective online learning experiences. Excellence in online education is important to Australia, socially and economically. Social benefits come from greater participation and graduates better equipped to contribute to their communities. Economic benefits come from graduates with skills and knowledge to be flexible, adaptable and productive in a dynamic workplace. As high quality online education providers, Australian universities will be more competitive in the international education market. This project will raise the profile of Australian research and lead to new commercial ventures through the development of innovative technologies for online learning.Read moreRead less
Re-balancing global resources: Manipulating toxic prussic acid (dhurrin) to improve nitrogen use efficiency in forage sorghum in a changing climate. Sorghum is grown widely is Australia and world-wide for forage, grain (mostly for animal feed) and biofuels. It grows well in dry areas. The problem is that the leaves contain a toxin that releases prussic acid (cyanide) that can reduce animal production or even kill stock feeding on it, especially when water stressed. The problem will get worse wit ....Re-balancing global resources: Manipulating toxic prussic acid (dhurrin) to improve nitrogen use efficiency in forage sorghum in a changing climate. Sorghum is grown widely is Australia and world-wide for forage, grain (mostly for animal feed) and biofuels. It grows well in dry areas. The problem is that the leaves contain a toxin that releases prussic acid (cyanide) that can reduce animal production or even kill stock feeding on it, especially when water stressed. The problem will get worse with climate change. Low-cyanide plants developed by us using non-GM methods grow fast, but accumulate nitrate instead which is also toxic. This is a waste of expensive fertiliser too. We aim to develop plants that divert resources to growth instead of toxins in order to reduce fertiliser use and help prepare for the future. The fast growing plants may also be useful as a biofuel crop.Read moreRead less
Working students: reconceptualising the doctoral experience. Doctoral education is traditionally conceptualised in policies and practices as about young, full-time students with no work or related commitments. However, nowadays, doctoral candidates constitute a diverse population working in various institutional, community and industry sites. Government, universities and students' associations need to reconceptualise contemporary doctoral candidates' working relationships to enhance doctoral edu ....Working students: reconceptualising the doctoral experience. Doctoral education is traditionally conceptualised in policies and practices as about young, full-time students with no work or related commitments. However, nowadays, doctoral candidates constitute a diverse population working in various institutional, community and industry sites. Government, universities and students' associations need to reconceptualise contemporary doctoral candidates' working relationships to enhance doctoral education and to realise its full potential in society. Using quantitative and qualitative approaches, the project breaks new ground through two related comprehensive and systematic studies of the doctoral-working experiences of full-time and part-time students. It will generate new conceptual frameworks, and tools for data collection and analysis.Read moreRead less
Girls and Information Communication Technology (ICT) Career Pathways: Tackling the Upper Middle School 'Turn Off'. This project aims to develop strategic responses to factors associated with girls forming such negative perceptions of Information Communication Technology during their upper middle school years that they overwhelmingly reject Information Communication Technology as an option for advanced study and future careers. This project will contribute towards Australia's National Research Pr ....Girls and Information Communication Technology (ICT) Career Pathways: Tackling the Upper Middle School 'Turn Off'. This project aims to develop strategic responses to factors associated with girls forming such negative perceptions of Information Communication Technology during their upper middle school years that they overwhelmingly reject Information Communication Technology as an option for advanced study and future careers. This project will contribute towards Australia's National Research Priority 3 of building and transforming frontier technologies to maximize creative, technological capability by collaboratively developing a strategic model for responding to factors identified as 'turning girls off Information Communication Technology'.Read moreRead less