Discovery Early Career Researcher Award - Grant ID: DE160100614
Funder
Australian Research Council
Funding Amount
$363,612.00
Summary
Evolutionary genomics and origin of the molluscan biomineralisation toolkit. The project aims to use new genomes from understudied lineages of Mollusca to identify the genes involved in shell formation (biomineralisation) and infer their function and evolutionary history. The ability of molluscs to biofabricate intricate and robust skeletal structures from sea water is encoded in their genomes. Understanding the ancestral biomineralisation toolkit is of great interest to materials science, which ....Evolutionary genomics and origin of the molluscan biomineralisation toolkit. The project aims to use new genomes from understudied lineages of Mollusca to identify the genes involved in shell formation (biomineralisation) and infer their function and evolutionary history. The ability of molluscs to biofabricate intricate and robust skeletal structures from sea water is encoded in their genomes. Understanding the ancestral biomineralisation toolkit is of great interest to materials science, which seeks to replicate molluscan biomineralisation in vitro for biomedical and other applications. Understanding the toolkit is an important first step toward synthetic biology techniques to 'print' structures like bones in vitro. Moreover, new genomic resources from molluscs will be of interest to researchers in numerous fields.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100379
Funder
Australian Research Council
Funding Amount
$420,582.00
Summary
Missing link in the chain: Gateway to the Satellite-Internet Constellations. This project aims to develop affordable and compact, reconfigurable antenna systems for satellite-terminals. With unprecedented performance, the wide bandwidth of operation, and low cost of production, the resulting antenna systems will act as the ‘enabling’ chip in providing internet connectivity to millions of people, who are unconnected or poorly connected at present. High-speed internet is not a reality outside dens ....Missing link in the chain: Gateway to the Satellite-Internet Constellations. This project aims to develop affordable and compact, reconfigurable antenna systems for satellite-terminals. With unprecedented performance, the wide bandwidth of operation, and low cost of production, the resulting antenna systems will act as the ‘enabling’ chip in providing internet connectivity to millions of people, who are unconnected or poorly connected at present. High-speed internet is not a reality outside densely populated areas, even today. The outcomes will close the digital divide, increase Australia’s economic and intellectual standing internationally, generate socio-economic benefits by empowering regional populations, increase the economic viability and remote-jobs outside metropolitan cities, and develop tourism.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100803
Funder
Australian Research Council
Funding Amount
$365,094.00
Summary
Impact of screen time on preschoolers’ social skills and cognitive function. This project aims to determine how the quantity and nature of screen time interacts with parental co-participation to affect pre-schoolers’ social skills and cognitive functioning. Seventy per cent of pre-schoolers exceed current screen time guidelines and this causes considerable concern among Australian parents. This project will assist in evaluating how much, and which types, of screen time have benefits for social ....Impact of screen time on preschoolers’ social skills and cognitive function. This project aims to determine how the quantity and nature of screen time interacts with parental co-participation to affect pre-schoolers’ social skills and cognitive functioning. Seventy per cent of pre-schoolers exceed current screen time guidelines and this causes considerable concern among Australian parents. This project will assist in evaluating how much, and which types, of screen time have benefits for social skills and cognitive functioning. It will also provide insights into the ways parents may best support these outcomes. Findings are expected to provide evidence for policy development and inform programs to support healthy behaviours to give young children the best start in life.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101595
Funder
Australian Research Council
Funding Amount
$364,446.00
Summary
Knowledge-embedded motion planning for smart construction machinery. This project aims to develop a novel sensory feedback-based planning approach for construction machinery to optimise site execution effectiveness. The project will investigate current motion planning approaches which are feasible as planning tools but fail to be implemented at construction sites due to uncertainties of actual operations. The expected outcome will be a practical planning approach validated through field tests an ....Knowledge-embedded motion planning for smart construction machinery. This project aims to develop a novel sensory feedback-based planning approach for construction machinery to optimise site execution effectiveness. The project will investigate current motion planning approaches which are feasible as planning tools but fail to be implemented at construction sites due to uncertainties of actual operations. The expected outcome will be a practical planning approach validated through field tests and help solve feasibility problems in handling deviations between plans and on-site executions.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100692
Funder
Australian Research Council
Funding Amount
$417,842.00
Summary
Stopping in the Real World: Cognitive Architectures for Selective Stopping. Response inhibition is the ability to stop actions that are in progress but become no longer appropriate, such as halting an order to launch a missile strike when a civilian vehicle is detected. The project focuses on people’s ability to either stop all planned actions or selectively stop some actions while allowing others to occur. The goal is to develop methodology to reliably measure the time it takes to stop actions, ....Stopping in the Real World: Cognitive Architectures for Selective Stopping. Response inhibition is the ability to stop actions that are in progress but become no longer appropriate, such as halting an order to launch a missile strike when a civilian vehicle is detected. The project focuses on people’s ability to either stop all planned actions or selectively stop some actions while allowing others to occur. The goal is to develop methodology to reliably measure the time it takes to stop actions, investigate the psychological mechanisms involved in stopping, and develop tools for defence-related personnel and job selection. The project provides significant benefits by enabling the study of how response inhibition ensures that appropriate actions occur and how failures of inhibition result in inappropriate actions. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101896
Funder
Australian Research Council
Funding Amount
$436,875.00
Summary
Interface engineering of 2D materials for advanced battery application. The fast-growing energy storage market demands new devices with both high energy and power density. This project aims to understand and then engineering electrode-electrolyte interfaces using novel two-dimensional (2D) materials to achieve accelerated ion transport and enhanced surface redox reactions. Advanced in-situ and ex-situ characterization tools, including X-ray scattering, neutron scattering, and terahertz time-doma ....Interface engineering of 2D materials for advanced battery application. The fast-growing energy storage market demands new devices with both high energy and power density. This project aims to understand and then engineering electrode-electrolyte interfaces using novel two-dimensional (2D) materials to achieve accelerated ion transport and enhanced surface redox reactions. Advanced in-situ and ex-situ characterization tools, including X-ray scattering, neutron scattering, and terahertz time-domain spectroscopy, will be employed to study energy storage mechanisms. Novel solid-state batteries will be demonstrated based on well-designed electrodes using 2D materials. This project will boost the standing of Australia in the global competition of developing more efficient energy storage devices. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101535
Funder
Australian Research Council
Funding Amount
$363,000.00
Summary
Ancient genomics of Western Australian taxa to inform conservation management. The project aims to apply genomic approaches to infer the genetic health and evolutionary history of three threatened, iconic Western Australian taxa: black cockatoos, ghost bats and woylies. Genomic data provide a powerful lens through which to study species, but the applications of genomic techniques in conservation biology have been sparse. Effective restoration and conservation initiatives require an understanding ....Ancient genomics of Western Australian taxa to inform conservation management. The project aims to apply genomic approaches to infer the genetic health and evolutionary history of three threatened, iconic Western Australian taxa: black cockatoos, ghost bats and woylies. Genomic data provide a powerful lens through which to study species, but the applications of genomic techniques in conservation biology have been sparse. Effective restoration and conservation initiatives require an understanding of species' former population sizes, connectivity and biodiversity. The project seeks to elucidate the population genetic, phylogenetic, and conservation genetic parameters of the three species at the genomic level using DNA isolated from modern and ancient sources (eg museum skins and fossils). The information gained may inform conservation efforts for some of Australia’s endangered biota.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100998
Funder
Australian Research Council
Funding Amount
$444,576.00
Summary
Should I stay or should I go? How brain stem cells leave quiescence. Most adult stem cells in our brains are sleeping (quiescent). Quiescence helps ensure animals have a lifelong population of brain stem cells, which is crucial for the maintenance of brain circuitry. This project aims to investigate how this process is regulated at a molecular level. This project expects to define the molecular playbook controlling quiescence and explain why brain stem cells progress into deeper states of quiesc ....Should I stay or should I go? How brain stem cells leave quiescence. Most adult stem cells in our brains are sleeping (quiescent). Quiescence helps ensure animals have a lifelong population of brain stem cells, which is crucial for the maintenance of brain circuitry. This project aims to investigate how this process is regulated at a molecular level. This project expects to define the molecular playbook controlling quiescence and explain why brain stem cells progress into deeper states of quiescence during aging by combining novel tissue culture and genetic models, where brain stem cells have disrupted quiescence, with innovative methods of reading gene expression. The benefits of these outcomes include the development of methods to control the quiescence of brain stem cells for bioengineering purposes.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100793
Funder
Australian Research Council
Funding Amount
$463,180.00
Summary
Unraveling a new cytokine working model in immune cell exhaustion. This project will investigate a novel paradigm of how a key messenger protein can be sensed by fundamental immune cells, preventing their ‘exhaustion’. Immune cell exhaustion is a fundamental mechanism to maintain the internal homeostasis of vertebrates. However, it is often hijacked by pathogens to dampen the defensive capacity of the immune system. And this specific messenger protein is the only known soluble factor that can d ....Unraveling a new cytokine working model in immune cell exhaustion. This project will investigate a novel paradigm of how a key messenger protein can be sensed by fundamental immune cells, preventing their ‘exhaustion’. Immune cell exhaustion is a fundamental mechanism to maintain the internal homeostasis of vertebrates. However, it is often hijacked by pathogens to dampen the defensive capacity of the immune system. And this specific messenger protein is the only known soluble factor that can deliver ‘anti-exhaustion’ signals to immune cells. This study will advance basic knowledge in biochemistry and immunology by combining interdisciplinary and cutting-edge approaches. The expected outcomes include the developing new scientific theories and identifying novel molecular basis of biological processes. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100803
Funder
Australian Research Council
Funding Amount
$405,763.00
Summary
Slicing dead stars to reveal the origin of heavy elements in the Universe. This project aims to improve our understanding of how massive stars forge heavy elements like oxygen, that are key to life. It will use state-of-the-art spectrographs on Australian and Chilean telescopes to observe the ashes of dead stars, and test recent theoretical models. Expected outcomes include spectral maps of young supernova remnants, new observational constraints for theoretical models of massive stars and core-c ....Slicing dead stars to reveal the origin of heavy elements in the Universe. This project aims to improve our understanding of how massive stars forge heavy elements like oxygen, that are key to life. It will use state-of-the-art spectrographs on Australian and Chilean telescopes to observe the ashes of dead stars, and test recent theoretical models. Expected outcomes include spectral maps of young supernova remnants, new observational constraints for theoretical models of massive stars and core-collapse supernovae, and innovative visualization solutions for complex 3D datasets. This project is expected to largely refine our grasp of the formation of heavy elements in the Universe, and thus provide significant cultural benefit in enhancing our understanding of mankind's cosmic origin in the heart of massive stars. Read moreRead less