REdefining metabolic Schemes and Pathways In plant leaf REspiration. Leaf respiration-related metabolism in terrestrial vegetation liberates considerable amounts of carbon dioxide, ammonia and hydrogen sulphide into the atmosphere. Such gaseous losses are detrimental to biomass production but respiration also sustains nutrient assimilation and biosyntheses. This project aims to describe flux patterns in respiratory metabolism and disentangle interactions with other pathways such as photorespirat ....REdefining metabolic Schemes and Pathways In plant leaf REspiration. Leaf respiration-related metabolism in terrestrial vegetation liberates considerable amounts of carbon dioxide, ammonia and hydrogen sulphide into the atmosphere. Such gaseous losses are detrimental to biomass production but respiration also sustains nutrient assimilation and biosyntheses. This project aims to describe flux patterns in respiratory metabolism and disentangle interactions with other pathways such as photorespiration and nitrogen assimilation. It will exploit stable isotopes to quantify metabolic partitioning and show coordination between major processes. It will establish key mechanisms by which respiration dictates plant carbon balance and contributes to identifying metabolic bottle-necks in plant primary production.Read moreRead less
A new management tool for effective wastewater source control. The use of recycled wastewater can dramatically increase the water supply capacity. However, the potential health risk from possible containments in recycled wastewater must be mitigated. This project aims to develop an effective wastewater source management tool for safeguarding the recycled water production and usage.
Special Research Initiatives - Grant ID: SR180100005
Funder
Australian Research Council
Funding Amount
$1,225,000.00
Summary
Remediation of PFAS contaminated soil using soil washing and immobilisation. This project aims to assess the applicability of soil washing and immobilisation as cost-effective techniques for the remediation of per- and poly-fluroalkyl substance (PFAS) contaminated Australian soils. The project expects to establish the efficacy of the remediation of a range of PFASs, including many polyfluorinated precursors of perfluorinated, chemically-persistent legacy pollutants which are of concern. The proj ....Remediation of PFAS contaminated soil using soil washing and immobilisation. This project aims to assess the applicability of soil washing and immobilisation as cost-effective techniques for the remediation of per- and poly-fluroalkyl substance (PFAS) contaminated Australian soils. The project expects to establish the efficacy of the remediation of a range of PFASs, including many polyfluorinated precursors of perfluorinated, chemically-persistent legacy pollutants which are of concern. The project will provide a scientific basis for understanding the benefits and limitations associated with soil washing and immobilisation techniques and a more comprehensive understanding of future liabilities associated with formation of PFASs from precursors remaining in remediated soils. Collaboration with stakeholders will ensure benefits are captured both commercially and environmentally, as well as removing a potential and on-going health threat to communities exposed to these contaminants.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100032
Funder
Australian Research Council
Funding Amount
$240,000.00
Summary
Ultra-high-performance liquid chromatography ion trap mass spectrometer to develop new capabilities in environmental and human toxicology. This facility will be dedicated to developing methods and analyses of environmental contaminants and by-products that are currently not well understood. Having this analytical capability will underpin leading research in environmental toxicology and chemistry, and will help to minimise environmental and human exposure to harmful contaminants.
Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge ....Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge regarding the function of the CNS and deliver complex human cellular systems, that have both discovery and commercial applications.
Benefit: These platforms will have subsequent application revealing the mechanisms underlying numerous neurological diseases, with capacity to upscale for rapid drug screening.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100094
Funder
Australian Research Council
Funding Amount
$220,000.00
Summary
Macromolecular characterisation and purification facility. In-depth characterisation of (bio)macromolecules and nanomaterials is fundamental to understanding their properties and application to advanced materials and technologies. The three new instruments at this facility dedicated to the purification, separation and characterisation of these compounds will provide an essential resource for polymer/materials research.
New strategies for highly sensitive chemical detection based on luminescent ruthenium and iridium complexes. Chemical reactions that emit tiny quantities of light, not even visible to the naked eye, can be used to detect the biomarkers of disease or traces of chemical or biological weapons in a terrorist attack. This project creates a new generation of reagents for this remarkably sensitive mode of detection for these and other important applications.
Green sample preparation technologies for analytical chemistry. This project opens new directions for the sample preparation of small molecules, nanoparticles and bacterial cells prior to analysis and will reduce pollution from chemical laboratories. The proposed 'green' analytical chemistry techniques will strengthen the position of Australia as a world-leader in separation science.
Discovery Early Career Researcher Award - Grant ID: DE200101785
Funder
Australian Research Council
Funding Amount
$424,978.00
Summary
Viewing Chemistry through Diamond: Quantum Sensors for Realtime in situ NMR. This project aims to develop a new analytical method and integrated platform technology for time dependent, in situ monitoring of chemical reactions. The proposed research will capitalise on recent developments made in the field of diamond-based quantum sensing to enable the resolution of chemical species and their concentrations within the timescales associated with many important reaction systems. This project thus ex ....Viewing Chemistry through Diamond: Quantum Sensors for Realtime in situ NMR. This project aims to develop a new analytical method and integrated platform technology for time dependent, in situ monitoring of chemical reactions. The proposed research will capitalise on recent developments made in the field of diamond-based quantum sensing to enable the resolution of chemical species and their concentrations within the timescales associated with many important reaction systems. This project thus expects to generate knowledge in both quantum metrology and physical chemistry. Moreover, the realisation of this technology has significant potential to improve the design and manufacture of important advanced materials, ranging from clean energy production and storage, to pharmaceutical development and drug discovery.Read moreRead less