Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775590
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
A single crystal X-ray diffractometer with CCD detector for structural analysis of small molecules. In recent years their have been major advances in the capacity of instrumentation to determine the crystal and molecular structure of chemical compounds and materials which in turn has resulted in a rapidly growing understanding of the relationship between the structure of molecules and their function in the design of new materials and as drugs for the treatment of disease and pain. This infrastr ....A single crystal X-ray diffractometer with CCD detector for structural analysis of small molecules. In recent years their have been major advances in the capacity of instrumentation to determine the crystal and molecular structure of chemical compounds and materials which in turn has resulted in a rapidly growing understanding of the relationship between the structure of molecules and their function in the design of new materials and as drugs for the treatment of disease and pain. This infrastructure also provides training of an international standard for undergraduate and post graduate students, thus building the skills capabilities of Australian scientists in the workforce.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346733
Funder
Australian Research Council
Funding Amount
$399,466.00
Summary
Ultra-Sensitive CCD Diffractometer with High Intensity X-ray Photon Generator. X-ray photon diffraction from single crystals provides the most accurate, precise and detailed three dimensional chemical structure information. It is however often difficult to obtain crystals of complex chemical assemblies, such as those used in nanotechnology and photon technology, suitable for diffraction analysis using equipment currently available at Australian chemical crystal structure facilities. The collab ....Ultra-Sensitive CCD Diffractometer with High Intensity X-ray Photon Generator. X-ray photon diffraction from single crystals provides the most accurate, precise and detailed three dimensional chemical structure information. It is however often difficult to obtain crystals of complex chemical assemblies, such as those used in nanotechnology and photon technology, suitable for diffraction analysis using equipment currently available at Australian chemical crystal structure facilities. The collaborating institutions seek to overcome this problem by purchasing a high sensitivity CCD area detector coupled to an intense laboratory source of X-ray photons. The installation of the equipment would be the first of its kind at an Australian facility and only the fourth worldwide.Read moreRead less
Negative ion mass spectrometry: fundamentals and applied applications. 1. We seek to establish negative ion mass spectrometry as a major technological tool for the sequencing of peptides and proteins. In this context, we will investigate the structures and modes of action of peptide complexes which may be of importance for the treatment and control of heart disease and stroke.
2. Negative ions of known structure will be converted (in the mass spectrometer) into transient (and reactive) molecule ....Negative ion mass spectrometry: fundamentals and applied applications. 1. We seek to establish negative ion mass spectrometry as a major technological tool for the sequencing of peptides and proteins. In this context, we will investigate the structures and modes of action of peptide complexes which may be of importance for the treatment and control of heart disease and stroke.
2. Negative ions of known structure will be converted (in the mass spectrometer) into transient (and reactive) molecules which are present in interstellar ice and dust clouds. The structures and chemistry of such molecules are of importance in understanding the origins of life on this planet.Read moreRead less