Development of electrophoretic cell sorters. The aim of this research is to develop the next generation of cell sorters to scale production of viable sperm and other cell types. Our approach is to understand the factors that control the migration of cells in an electric field so that we can design large-scale devices to purify cells using electrophoretic separation. The outcomes of this research enable large-scale production of viable sperm for human and animal-assisted conception, benefiting in ....Development of electrophoretic cell sorters. The aim of this research is to develop the next generation of cell sorters to scale production of viable sperm and other cell types. Our approach is to understand the factors that control the migration of cells in an electric field so that we can design large-scale devices to purify cells using electrophoretic separation. The outcomes of this research enable large-scale production of viable sperm for human and animal-assisted conception, benefiting infertile couples and the livestock breeding industry. Successful development of an efficient cell separation technology would add significant commercial value to the Australian biomanufacturing sector. Read moreRead less
In vivo molecular imaging using engineered affinity reagents and fluorescent laser scanning confocal endomicroscopy. The goal of this project is to develop laser scanning confocal endomicroscopy as a tool for basic scientific discovery and rapid detection of disease biomarkers. The cutting-edge instrument and associated technologies will provide scientists with unprecedented access to dynamic biological processes as they occur in real-time. In addition, it will enable the development of virtual ....In vivo molecular imaging using engineered affinity reagents and fluorescent laser scanning confocal endomicroscopy. The goal of this project is to develop laser scanning confocal endomicroscopy as a tool for basic scientific discovery and rapid detection of disease biomarkers. The cutting-edge instrument and associated technologies will provide scientists with unprecedented access to dynamic biological processes as they occur in real-time. In addition, it will enable the development of virtual biopsies and instant diagnosis without the need for costly and time-consuming histopathological reports. Thus, it will not only drive transformative research but also transform health care delivery. It will also be a major boost to the Australian biotechnology industry with potential for enormous economic benefits.Read moreRead less
Multifunctional surfaces for implantable biomedical devices. This project aims to improve the quality of life of patients receiving biomedical implants. The project will develop new plasma processing methods to create surfaces for implants that will give control over the response of human tissues. Tissue integration with the device will be achieved where required and infection suppressed.