The ApoE Interactome in Human Plasma. In this, the post-genome era, the emphasis has switched from the delineation of genome structure to the tremendous task of characterizing the gene products. One of the important aspects evolving in this new era is the design of strategies that enable identification of global protein-protein interactions, defined by the Human Proteome Organisation as the interactome. This, the apoE interactome in human plasma project, will identify novel interactions between ....The ApoE Interactome in Human Plasma. In this, the post-genome era, the emphasis has switched from the delineation of genome structure to the tremendous task of characterizing the gene products. One of the important aspects evolving in this new era is the design of strategies that enable identification of global protein-protein interactions, defined by the Human Proteome Organisation as the interactome. This, the apoE interactome in human plasma project, will identify novel interactions between plasma proteins and apoE, which is a lipid-binding protein genetically linked to age-related diseases affecting more than 500,000 Australians. This project will therefore provide scope for novel treatments and early detection of disease, namely cardiovascular and Alzheimer's disease.Read moreRead less
Single molecule spectroscopy of functional luminescent materials. This project will provide new insights into the light induced processes occurring in individual molecules of potentially useful luminescent materials. The molecules to be studied include new fluorescent probes of biological and polymer systems and single light harvesting nanoparticles with applications in solar energy collection and conversion. The program of work proposed will increase our understanding of light induced chemical ....Single molecule spectroscopy of functional luminescent materials. This project will provide new insights into the light induced processes occurring in individual molecules of potentially useful luminescent materials. The molecules to be studied include new fluorescent probes of biological and polymer systems and single light harvesting nanoparticles with applications in solar energy collection and conversion. The program of work proposed will increase our understanding of light induced chemical processes and assist the design of advanced materials for photomolecular devices.Read moreRead less
Materials World Network Synthesis and Processing Optoelectronic Materials in Supercritical and Condensed Phase Carbon Dioxide. The Australian partner will have leveraged access to the skill base and facilities of the Cornell Center for Materials Research, and the NSF MRSEC that leads the world in frontier technologies in advanced materials. The partnership will deliver to Australia progress in national priority goals "Frontier Technologies" and new manufacturing technologies in environmentally ....Materials World Network Synthesis and Processing Optoelectronic Materials in Supercritical and Condensed Phase Carbon Dioxide. The Australian partner will have leveraged access to the skill base and facilities of the Cornell Center for Materials Research, and the NSF MRSEC that leads the world in frontier technologies in advanced materials. The partnership will deliver to Australia progress in national priority goals "Frontier Technologies" and new manufacturing technologies in environmentally friendly media that will enhance the national research priority "An Environmentally Sustainable Australia". New transferable skills will be acquired by the participants in the project. Technology transfer could result in the formation of spinoff companies to exploite the intellectual property arising in the project.Read moreRead less
Advanced Polymer Electrolytes for Device Applications. The future of an energy sustainable society relies upon the development of a range of technologies that will involve devices such as lithium batteries, supercapacitors, sensors and fuel cells. One of the key challenges is the discovery and development of high performance materials which overcome performance limiting issues such as conductivity, durability and stability in current devices. Our recent discovery of novel successful approaches ....Advanced Polymer Electrolytes for Device Applications. The future of an energy sustainable society relies upon the development of a range of technologies that will involve devices such as lithium batteries, supercapacitors, sensors and fuel cells. One of the key challenges is the discovery and development of high performance materials which overcome performance limiting issues such as conductivity, durability and stability in current devices. Our recent discovery of novel successful approaches to the design of improved electrolyte materials will be systematically exploited to develop materials that will provide the significant advance in device performance that is required.Read moreRead less
New Transparent Polymer Nanocomposite Coatings Using Multireactive Inorganic Cages. New polymeric nanocomposite coatings are proposed with enhanced abrasion resistance, toughness and optical functionality, suitable for the coating of optical plastic substrates. These composites contain inorganic cages, dispersed and chemically-coupled within the crosslinked organic matrix. In addition to good mechanical behaviour, high value properties such as colorisation on exposure to light and resistance to ....New Transparent Polymer Nanocomposite Coatings Using Multireactive Inorganic Cages. New polymeric nanocomposite coatings are proposed with enhanced abrasion resistance, toughness and optical functionality, suitable for the coating of optical plastic substrates. These composites contain inorganic cages, dispersed and chemically-coupled within the crosslinked organic matrix. In addition to good mechanical behaviour, high value properties such as colorisation on exposure to light and resistance to damage from high energy lasers will be achieved by attachment to the cages of chemical units with optical activity. These cages are of nanometre size and an important aspect of the project involves probing the resultant structure at the molecular level, using advanced characterisation techniques.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882576
Funder
Australian Research Council
Funding Amount
$588,000.00
Summary
Polymer Characterization Facility (PCF). Future development of macromolecular and biotechnologies have the potential to revolutionize everyday life. Current applications include plastics for engineering, diagnostic devices for biochemical analysis, polymer therapeutics for drug delivery and prosthesis with specific functions. The proposed facility will provide the analytical tools required to probe and develop advanced materials with application in medicine, agriculture, composites, cosmetics, ....Polymer Characterization Facility (PCF). Future development of macromolecular and biotechnologies have the potential to revolutionize everyday life. Current applications include plastics for engineering, diagnostic devices for biochemical analysis, polymer therapeutics for drug delivery and prosthesis with specific functions. The proposed facility will provide the analytical tools required to probe and develop advanced materials with application in medicine, agriculture, composites, cosmetics, communications and electronics.Read moreRead less
The Synthesis and Evaluation of White Nano Particles that Reinforce the Mechanical Properties of Elastomers. This project will introduce admicellar polymerization technique to produce a bound polymer layer on the surface of fillers used for reinforcement of elastomers. The novel approach in this project will provide advanced material with excellent mechanical properties. Such composites can be used in various high performance elastomer applications such as rubber for tyres in automotive vehicles ....The Synthesis and Evaluation of White Nano Particles that Reinforce the Mechanical Properties of Elastomers. This project will introduce admicellar polymerization technique to produce a bound polymer layer on the surface of fillers used for reinforcement of elastomers. The novel approach in this project will provide advanced material with excellent mechanical properties. Such composites can be used in various high performance elastomer applications such as rubber for tyres in automotive vehicles. Products based on this new technology will produce significantly improved properties. The development of this new technology will not only advance polymer science, it will also provide great opportunities for new elastomer applications in a number of industries.Read moreRead less
Characterization of star nanogels by advanced transmission electron microscopy. This project will provide an excellent opportunity to combine research expertise from The Polymer Science Group at The University of Melbourne and The Polymer Morphology Group at North Carolina State University (NCSU) to develop and characterize novel star nanogels with unique macromolecular architectures. The success of the project will reveal the absolute structures of these molecules and the proposed studies are b ....Characterization of star nanogels by advanced transmission electron microscopy. This project will provide an excellent opportunity to combine research expertise from The Polymer Science Group at The University of Melbourne and The Polymer Morphology Group at North Carolina State University (NCSU) to develop and characterize novel star nanogels with unique macromolecular architectures. The success of the project will reveal the absolute structures of these molecules and the proposed studies are both intellectually challenging in the cutting-edge of leading research in the field and important to provide vital information for the design of new structures of these new materials for their application in many areas, such as drug delivery, new membrane formation, advance high density memory chips and possibly the next generation of automotive coating.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346891
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Characterization facilities for new macromolecular architectures. The proposed facility is essential for characterization of the new polymeric architectures such as copolymers for tissue engineering, nanogels for automotive paints and biodegradable polymeric packaging. The facilities include characterizations of (1) molar mass and molecular sizes of novel polymer architectures (MU); (2) viscoelastic mechanical properties of tensile, bending, bulk and flow (RMIT); and (3) thermal properties of c ....Characterization facilities for new macromolecular architectures. The proposed facility is essential for characterization of the new polymeric architectures such as copolymers for tissue engineering, nanogels for automotive paints and biodegradable polymeric packaging. The facilities include characterizations of (1) molar mass and molecular sizes of novel polymer architectures (MU); (2) viscoelastic mechanical properties of tensile, bending, bulk and flow (RMIT); and (3) thermal properties of compositions (CSIRO). These new polymeric architectures cannot be sufficiently characterized by existing facilities. The success of the project will significantly enhance the new macromolecular research and facilitate collaborations. This project also falls within the nano and biomaterials of the Designated Priority area of Research.Read moreRead less
Novel Coatings For Steel. The aim of this project is to design coatings for steel that have high flexibility and high resistance to scatching and hardness. This will be achieved by the introduction of liquid crystalline phases in the coatings. The outcome will be a new generation of steel coatings with novel properties