Vibrational Spectroscopy and Imaging from Interstellar Dust to Life. The outcome of this project will result in a more thorough understanding of the role of water in the atmosphere and in the Greenhouse effect, and will provide information leading to more accurate modelling of Global warming. The results will also lead to new insights into interstellar chemistry, the chemistry of cometary dust and the origins of life.
Porphyrin Based Supramolecular Assemblies and Arrays III - Model Systems for the Construction of Photosynthetic Mimics and Devices. Solar cells that convert light to electricity are an excellent solution to bringing energy to remote locations with abundant sunlight. This research proposal aims to provide an intellectual grounding in the development of molecular systems and supramolecular arrays that are capable of such solar energy conversion (photovoltaics & artificial photosynthesis) or that ....Porphyrin Based Supramolecular Assemblies and Arrays III - Model Systems for the Construction of Photosynthetic Mimics and Devices. Solar cells that convert light to electricity are an excellent solution to bringing energy to remote locations with abundant sunlight. This research proposal aims to provide an intellectual grounding in the development of molecular systems and supramolecular arrays that are capable of such solar energy conversion (photovoltaics & artificial photosynthesis) or that have potential applications in photonics. Developments in this project may also lead to breakthroughs in areas such as nano-scale computing and cleaner and more sustainable energy productionRead moreRead less
Single molecule spectroscopy of functional luminescent materials. This project will provide new insights into the light induced processes occurring in individual molecules of potentially useful luminescent materials. The molecules to be studied include new fluorescent probes of biological and polymer systems and single light harvesting nanoparticles with applications in solar energy collection and conversion. The program of work proposed will increase our understanding of light induced chemical ....Single molecule spectroscopy of functional luminescent materials. This project will provide new insights into the light induced processes occurring in individual molecules of potentially useful luminescent materials. The molecules to be studied include new fluorescent probes of biological and polymer systems and single light harvesting nanoparticles with applications in solar energy collection and conversion. The program of work proposed will increase our understanding of light induced chemical processes and assist the design of advanced materials for photomolecular devices.Read moreRead less
Characterization and design of new soft electrolyte materials. The use of fossil fuels for energy generation contributes heavily to global warming. The development of new types of energy sources (e.g. fuel cells) and energy storage devices (e.g. batteries) is of crucial importance to ease this pressure on the environment. The search for new, high energy-density electrolyte materials for these applications is intense. Recently, plastic crystal materials have been identified as potential electroly ....Characterization and design of new soft electrolyte materials. The use of fossil fuels for energy generation contributes heavily to global warming. The development of new types of energy sources (e.g. fuel cells) and energy storage devices (e.g. batteries) is of crucial importance to ease this pressure on the environment. The search for new, high energy-density electrolyte materials for these applications is intense. Recently, plastic crystal materials have been identified as potential electrolytes in a variety of electrochemical devices. These materials show high conductivity at ambient temperatures in their plastic (or soft) phase. This project aims to further investigate and develop these novel materials.Read moreRead less
Microprobe and Nanoprobe Studies on Intracellular Disease Processes and Their Treatment. Breakthrough microprobe and nanoprobe technologies, involving X-ray, visible and infrared light can focus into different components of mammalian cells in order to interrogate the biochemistry that is occurring therein. Each of the different wavelengths of light provides complementary biochemical information that enables a deeper understanding of changes in cells that occur as a function of drug treatments an ....Microprobe and Nanoprobe Studies on Intracellular Disease Processes and Their Treatment. Breakthrough microprobe and nanoprobe technologies, involving X-ray, visible and infrared light can focus into different components of mammalian cells in order to interrogate the biochemistry that is occurring therein. Each of the different wavelengths of light provides complementary biochemical information that enables a deeper understanding of changes in cells that occur as a function of drug treatments and disease processes. This will provide unprecedented information as to where drugs go and how they are transformed inside cells that, in turn, may revolutionalise the way in which new drugs are designed that have higher specificity and fewer side effects.Read moreRead less
Towards Nano-Assembled Light Emitting Polymer Films. Advanced materials constructed with molecular level architecture through controlled nano-assembly will benefit medical science, biotechnology and nanotechnology, communications and the electronics fields. The national research priorities of nanotechnology and advanced materials through nano-assembly will be promoted by this work. This research will assist Australian industries to further advance these processes and devices leading to better qu ....Towards Nano-Assembled Light Emitting Polymer Films. Advanced materials constructed with molecular level architecture through controlled nano-assembly will benefit medical science, biotechnology and nanotechnology, communications and the electronics fields. The national research priorities of nanotechnology and advanced materials through nano-assembly will be promoted by this work. This research will assist Australian industries to further advance these processes and devices leading to better quality, cheaper, more efficient products. The Australian community will benefit through economic and technological advances. These advanced materials will promote health and environmental wellbeing.Read moreRead less
Raman and synchrotron spectroscopy of nano-scale drug interactions and molecular processes in single living cells. The need for potent low-cost drugs is ever increasing, yet effective ways to screen for new drugs remain elusive. A spectroscopic approach to screening drugs in living cells would seem a logical alternative to chemically based and morphological methods that are the status quo. In this context we are developing methodology to analyse molecular target sites in single living cells for ....Raman and synchrotron spectroscopy of nano-scale drug interactions and molecular processes in single living cells. The need for potent low-cost drugs is ever increasing, yet effective ways to screen for new drugs remain elusive. A spectroscopic approach to screening drugs in living cells would seem a logical alternative to chemically based and morphological methods that are the status quo. In this context we are developing methodology to analyse molecular target sites in single living cells for two of the most devastating diseases to afflict human kind, namely malaria and cancer. New ways of rapidly screening drugs in living cells prior to clinical trials will save an enormous amount of time, money and ultimately lives.Read moreRead less
Energy transforming polymers: from single molecules to devices. Climate control and the rapidly increasing demand for energy is driving the search for alternative sustainable energy sources. Flexible plastics will be a primary component of the new generation of solar harvesting and energy conversion materials. The objective of this project is to gain an understanding of the way polymers interact with light and can convert absorbed solar energy into electrical power and other useful forms of ene ....Energy transforming polymers: from single molecules to devices. Climate control and the rapidly increasing demand for energy is driving the search for alternative sustainable energy sources. Flexible plastics will be a primary component of the new generation of solar harvesting and energy conversion materials. The objective of this project is to gain an understanding of the way polymers interact with light and can convert absorbed solar energy into electrical power and other useful forms of energy. The outcomes of the project will allow the improved design of plastics for applications in solar energy conversion.Read moreRead less
Lighting up the charged brigade: laser spectroscopy of protonated and metal-containing complexes. Increasingly, the design of new pharmaceuticals uses computer modeling to account for the shapes of molecules and how they interact with their surroundings. The strongest forces between molecular components are those that involve charged chemical species known as ions. In this project, we will develop advanced laser-based techniques to study in unprecedented detail how molecules respond to the prese ....Lighting up the charged brigade: laser spectroscopy of protonated and metal-containing complexes. Increasingly, the design of new pharmaceuticals uses computer modeling to account for the shapes of molecules and how they interact with their surroundings. The strongest forces between molecular components are those that involve charged chemical species known as ions. In this project, we will develop advanced laser-based techniques to study in unprecedented detail how molecules respond to the presence of nearby charge, or to acquiring charge themselves. Understanding the nature of these attractions, and the structural changes that they induce eventually results in more accurate computer models. This has relevance to fields that include the architecture of proteins, recognition of signaling molecules in the brain, and drug development.Read moreRead less
Development of an efficient oxygen-thiosulfate process for the recovery of gold from ores. Gold is currently recovered from the ore by a cyanide leaching process. This high risk procedure is used because there is currently no safe alternative. The research we propose to undertake will investigate a novel thiosulfate-oxygen process to dissolve gold. Successful completion of the project will identify the mechanism of the process and could lead to the replacement of the highly toxic cyanide with th ....Development of an efficient oxygen-thiosulfate process for the recovery of gold from ores. Gold is currently recovered from the ore by a cyanide leaching process. This high risk procedure is used because there is currently no safe alternative. The research we propose to undertake will investigate a novel thiosulfate-oxygen process to dissolve gold. Successful completion of the project will identify the mechanism of the process and could lead to the replacement of the highly toxic cyanide with the non toxic thiosulfate. Thus the proposed project has the potential to substantially alter the gold recovery process, particularly in an era where environmental and public concerns exist over the use of cyanide.Read moreRead less