Neural mechanisms of vestibular perception in zebrafish. This project aims to understand vestibular processing by removing physical movement. The vestibular system allows us to perceive gravity and movement, but it is not understood how the brain processes information from vestibular sensors in the inner ear. This project will exert forces on the zebrafish’s inner ear with a laser, stimulating the vestibular sense. This means that the animal will experience vestibular stimuli while stationary, a ....Neural mechanisms of vestibular perception in zebrafish. This project aims to understand vestibular processing by removing physical movement. The vestibular system allows us to perceive gravity and movement, but it is not understood how the brain processes information from vestibular sensors in the inner ear. This project will exert forces on the zebrafish’s inner ear with a laser, stimulating the vestibular sense. This means that the animal will experience vestibular stimuli while stationary, allowing calcium imaging of neurons that respond to vestibular cues and optogenetics to stimulate or silence these neurons. This is expected to reveal which cells and circuits mediate vestibular perception, processing and behaviour.Read moreRead less
Probe-free biophysical force and torque measurements with optical tweezers. This project aims to develop probe-free biophysical force and torque measurement methods based on optical tweezers. Many areas of research in cell biology are hampered by a lack of quantitative force measurements. This project aims to provide accurate quantitative measurements to enable in-depth understanding of forces at work during cell division, properties of blood cells and sperm motility which could generate further ....Probe-free biophysical force and torque measurements with optical tweezers. This project aims to develop probe-free biophysical force and torque measurement methods based on optical tweezers. Many areas of research in cell biology are hampered by a lack of quantitative force measurements. This project aims to provide accurate quantitative measurements to enable in-depth understanding of forces at work during cell division, properties of blood cells and sperm motility which could generate further research leading to health benefits.Read moreRead less
Securing the quantum internet with high-dimensional quantum systems. This project aims to develop experimental and theoretical tools for increasing security in the future quantum networks. This project expects to generate new knowledge in the area of quantum communication by leveraging on the properties of high-dimensional quantum systems. Expected outcomes of this project include novel protocols for quantum secret sharing that are resistant to experimental noise and an experimental implementati ....Securing the quantum internet with high-dimensional quantum systems. This project aims to develop experimental and theoretical tools for increasing security in the future quantum networks. This project expects to generate new knowledge in the area of quantum communication by leveraging on the properties of high-dimensional quantum systems. Expected outcomes of this project include novel protocols for quantum secret sharing that are resistant to experimental noise and an experimental implementation of such protocols. This should provide significant benefits to the development of the quantum internet and its security.Read moreRead less
Neural mechanisms of water flow perception and spatial integration. This project aims to develop a novel zebrafish platform for elucidating the circuits that mediate lateral line perception. The sensory modality by which fish detect and respond to water flow is poorly understood. This project proposes a novel preparation in the zebrafish model for applying controlled water flow using microfluidics, thereby stimulating the lateral line. Because the animal remains stationary, it is possible to per ....Neural mechanisms of water flow perception and spatial integration. This project aims to develop a novel zebrafish platform for elucidating the circuits that mediate lateral line perception. The sensory modality by which fish detect and respond to water flow is poorly understood. This project proposes a novel preparation in the zebrafish model for applying controlled water flow using microfluidics, thereby stimulating the lateral line. Because the animal remains stationary, it is possible to perform whole-brain calcium imaging of cells and circuits that respond to water flow, and to use optogenetics to stimulate or silence these neurons. This will reveal the circuitry mediating flow perception, and its relationship with other senses, in a way that has been previously impossible.Read moreRead less