The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling f ....The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling for a synergistic defence to adapt to the nanoparticle toxicity. The pioneering knowledge is the foundation for technologies targeting the interspecies metabolite cross-talking to overcome the resistance phenomena, ensuring a long-term efficacy of the alternative antimicrobial on the difficult-to-control pathogenic growth.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170101069
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Two-dimensional inorganic nanostructures for hydrogen evolution reaction. This project aims to synthesise highly active electrochemical catalysts of two-dimensional (2D) inorganic nanostructure for hydrogen evolution reaction (HER). The electrocatalysis of water to produce hydrogen gas could generate clean energy, but the platinum catalyst’s cost and low activity make it impractical. This project will develop 2D inorganic nanosheets with tuneable pores and electronic band structures, hybridised ....Two-dimensional inorganic nanostructures for hydrogen evolution reaction. This project aims to synthesise highly active electrochemical catalysts of two-dimensional (2D) inorganic nanostructure for hydrogen evolution reaction (HER). The electrocatalysis of water to produce hydrogen gas could generate clean energy, but the platinum catalyst’s cost and low activity make it impractical. This project will develop 2D inorganic nanosheets with tuneable pores and electronic band structures, hybridised with organic and/or inorganic semiconductor nanomaterials for HER, and use density functional theory calculation to investigate these hybridised nanosheets’ mechanisms for HER. These highly efficient and low-cost catalysts are expected to generate clean energy and create opportunities for Australian industries.Read moreRead less
From organo-mineral nanocomposite to Australian basins; an integrated approach to unconventional gas exploration and development. Gas production from unconventional shale reservoirs is a potential major energy boom in Australia that will lower carbon emissions over comparable coal and oil use. The geological controls of shale are currently too poorly understood to direct effective exploration. This project will be the largest international effort to develop this knowledge.