Special Research Initiatives - Grant ID: SR0354500
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Research Network in Microarray Technology. The primary aim of this proposal is to transform the premier genomic technology into a standard research tool; microarrays are now a priority for anyone studying the genetics underlying key biological processes. A principal challenge for the Australian research community is to capture all aspects of microarray technology and make them readily available. We will address these needs by developing a network to:
-establish regular research meetings,
- ....ARC Research Network in Microarray Technology. The primary aim of this proposal is to transform the premier genomic technology into a standard research tool; microarrays are now a priority for anyone studying the genetics underlying key biological processes. A principal challenge for the Australian research community is to capture all aspects of microarray technology and make them readily available. We will address these needs by developing a network to:
-establish regular research meetings,
-facilitate training in array methodologies and bioinformatics,
-co-ordinate innovation of technologies,-provide centralised data warehousing,
-provide access to automated high-level gene annotation,
-provide data mining tools,
-set standards for data management and exchangeRead moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668549
Funder
Australian Research Council
Funding Amount
$280,000.00
Summary
Major upgrade of the computing hardware and software for the widely used BioManager bioinformatic service. ANGIS has been an Australian national facility for bioinformatics since 1991, now with over 4000 users across 150 university schools or departments, government departments, hospitals and research institutes. The grant will provide the computer upgrade and software support needed to handle the enormous increases in database size and complexity and expand the service into new areas of bioinfo ....Major upgrade of the computing hardware and software for the widely used BioManager bioinformatic service. ANGIS has been an Australian national facility for bioinformatics since 1991, now with over 4000 users across 150 university schools or departments, government departments, hospitals and research institutes. The grant will provide the computer upgrade and software support needed to handle the enormous increases in database size and complexity and expand the service into new areas of bioinformatics. Bioinformatics is critical to much of modern biology, and the improvements will enhance research and data analysis in many areas of research, leveraging more value from the research being undertaken by users. Read moreRead less
Linking mutant zebrafish phenotypes with their underlying genetic lesions. Zebrafish mutants have been generated with many interesting abnormalities, but to understand these abnormalities, the defective genes must be identified by positional cloning. We seek to identify the defective genes underpinning four mutants. Mutant #562 develops a normal nervous system which then undergoes rapid degeneration. The mutant flotte lotte has abnormal gut development. Two mutants with defective early blood for ....Linking mutant zebrafish phenotypes with their underlying genetic lesions. Zebrafish mutants have been generated with many interesting abnormalities, but to understand these abnormalities, the defective genes must be identified by positional cloning. We seek to identify the defective genes underpinning four mutants. Mutant #562 develops a normal nervous system which then undergoes rapid degeneration. The mutant flotte lotte has abnormal gut development. Two mutants with defective early blood formation will be studied. We will establish techniques for several steps that will be useful for all zebrafish mapping projects. We expect the genetic characterization of these mutants to provide new insights into nerve cell survival, gut development, and blood formation.Read moreRead less