Smart Matrix™ approaches towards neo vascularisation in bone repair. Bone injuries cost Australia more than $1 billion annually. The development of a medical device combining novel pro-angiogenic technology, Smart Matrix™, with polymer scaffolds for treatment of bone defects by this project, will facilitate rapid development of a blood supply within the defect, aiding bone growth and reducing overall costs compared to current treatments.
Investigating a novel, physical adjuvant for improving immune responses of vaccines. This project will explore a new way to significantly improve vaccine immune responses: with practical devices that apply pressure on the skin - for the body to create its own, localised adjuvant. This is novel - completely different to today's adjuvants, which are chemicals put into our bodies.
Grain size refinement of near beta titanium alloys - a route to developing new advanced medical implants and devices. This project seeks to develop targeted material solutions for application in the manufacture of new and improved medical components, such as stents. This will be achieved by developing new biocompatible beta titanium alloys with mechanical properties and forming behaviour that are optimised for implant applications associated with endovascular procedures.