Computed microscopy: solving the inverse problem of optical microscopy to image deeper into biological tissue. This project aims to enable 3D optical microscopy to image deeper within tissue, ultimately aiding research fields such as neurobiology. This will be achieved by a foundational approach called computed cicroscopy that combines novel numerical methods, high performance computing and optical microscopy. This project aims to develop a 3D quantitative imaging method that will provide unprec ....Computed microscopy: solving the inverse problem of optical microscopy to image deeper into biological tissue. This project aims to enable 3D optical microscopy to image deeper within tissue, ultimately aiding research fields such as neurobiology. This will be achieved by a foundational approach called computed cicroscopy that combines novel numerical methods, high performance computing and optical microscopy. This project aims to develop a 3D quantitative imaging method that will provide unprecedented insight into the structure of tissue with sub-cellular detail. This information can then be used to computationally reverse light scattering within the sample, allowing fluorescence microscopy at unprecedented depths within tissue.Read moreRead less