Testing the free radical theory of aging: do indicators of oxidative damage predict lifespan? Because of the Free Radical Theory of Aging, many millions of dollars are spent around the world on dietary antioxidants of unproven efficacy. Many millions of research dollars are spent providing support for this theory but few studies test it rigorously. The first major benefit of this research is worldwide; to refute, or to substantially enhance and focus the current support for the Free Radical Theo ....Testing the free radical theory of aging: do indicators of oxidative damage predict lifespan? Because of the Free Radical Theory of Aging, many millions of dollars are spent around the world on dietary antioxidants of unproven efficacy. Many millions of research dollars are spent providing support for this theory but few studies test it rigorously. The first major benefit of this research is worldwide; to refute, or to substantially enhance and focus the current support for the Free Radical Theory. This should help to rationalise and direct funding supplied to these areas. The second benefit is for Australia: aging is a fruitful area for research because of the high general public interest and for training because of its multidisciplinary nature, and funding in Australia is very low by international standards. Read moreRead less
Predicting the effect of climate change on community structure and function: an assessment using temperate grassland invertebrates. This research will set the future agenda for assessing community responses to climate change worldwide. Our findings will be a robust template for future research to incorporate sophisticated multi-species assessments across all taxa and biomes. Results and conclusions from this research will aid graziers, agronomists, government agencies and conservation groups wor ....Predicting the effect of climate change on community structure and function: an assessment using temperate grassland invertebrates. This research will set the future agenda for assessing community responses to climate change worldwide. Our findings will be a robust template for future research to incorporate sophisticated multi-species assessments across all taxa and biomes. Results and conclusions from this research will aid graziers, agronomists, government agencies and conservation groups working in urban, rural and regional landscapes to prepare for changes in species relationships over the coming century. The team of early career researchers will also prepare the next generation of scientists for cutting edge ecological and statistical research within a dynamic and multidisciplinary context.Read moreRead less
Modelling species distributions for a changing world. Understanding the impacts of climate change and invasive species on the distribution and persistence of species is an issue of global and national significance and concern. This project will provide tools essential for the effective management of Australia's ecosystems by delivering clear guidelines and practical methods that will substantially improve the modelling of future species distributions.
SCP/TAPS proteins of the barber’s pole worm. This integrated, collaborative project, will explore, in a targeted way, the structure and function of a key group of molecules in a socio-economically important eukaryotic pathogen and their involvement in pathogen-host interactions. Fundamental knowledge and understanding of these molecules will provide a solid foundation for understanding disease processes and finding new intervention strategies for a range of pathogens. This is crucial, given the ....SCP/TAPS proteins of the barber’s pole worm. This integrated, collaborative project, will explore, in a targeted way, the structure and function of a key group of molecules in a socio-economically important eukaryotic pathogen and their involvement in pathogen-host interactions. Fundamental knowledge and understanding of these molecules will provide a solid foundation for understanding disease processes and finding new intervention strategies for a range of pathogens. This is crucial, given the serious drug resistance problems in pathogens, and residue problems in meat, milk and the environment.Read moreRead less
Sustainable futures of Australian temperate forests: An investigation of coupled carbon, water and energy exchanges from hourly to centennial timescales. Australia's forests are a critical natural resource that must be sustainably managed. We will determine the uptake/release of carbon from old growth and regrowth forests and assess the water budgets of the Melbourne water catchment. We aim to understand the current cycles of carbon, water and energy and how these may change over time (hours to ....Sustainable futures of Australian temperate forests: An investigation of coupled carbon, water and energy exchanges from hourly to centennial timescales. Australia's forests are a critical natural resource that must be sustainably managed. We will determine the uptake/release of carbon from old growth and regrowth forests and assess the water budgets of the Melbourne water catchment. We aim to understand the current cycles of carbon, water and energy and how these may change over time (hours to centuries). We will integrate our observations with state-of-the-art models to improve our predictions of how forests will respond to change. This will aid our management of forests and forested catchments to ensure sustainable and viable water resources and optimise carbon sequestration.Read moreRead less
Australian savannah landscapes: past, present and future. Australian savannahs are productive and culturally and biologically significant landscapes but are vulnerable to climate change. The project will determine savannah function (carbon and water balance) for the present and assess how sensitive they have been to past climate variability. The project will then address how they may respond to future climate change.
Patterns and processes of carbon and water budgets across northern Australian landscapes: From point to region. Quantifying carbon sources and sinks and understanding the underlying processes are pre-requisites to informed policy decisions, especially as nations seek to develop strategies to manage carbon emissions and sequestration. Australia is unique because of its poor soils and high climate variability and is likely to have patterns and process of carbon that are globally different. We fo ....Patterns and processes of carbon and water budgets across northern Australian landscapes: From point to region. Quantifying carbon sources and sinks and understanding the underlying processes are pre-requisites to informed policy decisions, especially as nations seek to develop strategies to manage carbon emissions and sequestration. Australia is unique because of its poor soils and high climate variability and is likely to have patterns and process of carbon that are globally different. We focus on Australia's Top-End region, but will develop tools/methods that can be applied to other important Australian hot-spots. This project will support the existing National Carbon Accounting System by providing new information on processes and spatial variability and regional budgets of carbon and water budgets that underpin our international commitments.Read moreRead less
Understanding responses to climate change: a mechanistic approach integrating functional genetics, physiology and biophysical models for the Common brown butterfly. We will dissect the interaction between an Australian butterfly and changing climate. This will make significant contributions to the national research priorities Responding to climate change and variability and Sustainable use of Australia's biodiversity. We will address the known deficits in standard approaches to predicting futu ....Understanding responses to climate change: a mechanistic approach integrating functional genetics, physiology and biophysical models for the Common brown butterfly. We will dissect the interaction between an Australian butterfly and changing climate. This will make significant contributions to the national research priorities Responding to climate change and variability and Sustainable use of Australia's biodiversity. We will address the known deficits in standard approaches to predicting futures for biota. We will provide an Australian species in which the mechanisms of response to climate change are understood in detail. Our outputs will be directly applicable to other butterflies: 19 threatened taxa in Australia. The novelty of our approach will be of marked international interest, and will train Australian researchers in a new way of predicting biological impacts of climate change.Read moreRead less
Infrakingdom Alveolata: searching for a defining structural feature. This project will establish the first molecular nexus between a cellular structure currently used to define an Infrakingdom of life. It will aid in the higher order systematics of our microscopic diversity and allow us to interpret how important parasites learned to penetrate host cells to establish infection. We will train excellent graduate and Honours students in cellular and molecular biology.