Synthetic and theoretical studies of metal complexes containing carbon-rich ligands. Previous studies in my group, in conjunction with synthetic and theoretical chemistry groups at the Université de Rennes 1, France, have delineated the properties of a series of complexes containing carbon chains linking two metal centres. Having achieved a partial understanding of the features which result in good electronic communication between the metal centres via the carbon chain, the present proposal see ....Synthetic and theoretical studies of metal complexes containing carbon-rich ligands. Previous studies in my group, in conjunction with synthetic and theoretical chemistry groups at the Université de Rennes 1, France, have delineated the properties of a series of complexes containing carbon chains linking two metal centres. Having achieved a partial understanding of the features which result in good electronic communication between the metal centres via the carbon chain, the present proposal seeks to extend this collaboration to further studies which will generate related compounds in which actual eletron exchange can occur, i.e. leading to oxidation/reduction, by using compounds in which two or more different metal centres are present. This may lead to development of nano devices, e.g. molecular-scale switches. If one of the centres is activated by light, a photo-active sensor may result.Read moreRead less
Multipurpose separation platforms for protein purification. Over the next decades, many new therapies and products will be needed to enhance the quality of human life. Biopharmaceuticals and other protein-based products will thus be increasingly in demand. This will require significant improvements in biotechnological procedures, particularly sophisticated purification technologies. Through the development of a novel technology, this project is anticipated to significantly contribute to these so ....Multipurpose separation platforms for protein purification. Over the next decades, many new therapies and products will be needed to enhance the quality of human life. Biopharmaceuticals and other protein-based products will thus be increasingly in demand. This will require significant improvements in biotechnological procedures, particularly sophisticated purification technologies. Through the development of a novel technology, this project is anticipated to significantly contribute to these societal needs and provide a new way to purify these important molecules. National and community benefits will accrue from this scientific innovation and from its application, which is expected to provide more efficient manufacturing opportunities for key biotechnology industries.Read moreRead less
Single walled carbon nanotubes of one stereochemistry - material for the oncoming carbon age. Carbon nanotubes are finding application in nanotechnology. However currently they are prepared as a mixture of zig-zag, chiral and armchair isomers. Their properties could be improved if they could be prepared with one stereochemistry. The approach here is to use a nanocrystallisation and thermal maturation process involving stereo controlling additives. The new carbons are expected to have outstandin ....Single walled carbon nanotubes of one stereochemistry - material for the oncoming carbon age. Carbon nanotubes are finding application in nanotechnology. However currently they are prepared as a mixture of zig-zag, chiral and armchair isomers. Their properties could be improved if they could be prepared with one stereochemistry. The approach here is to use a nanocrystallisation and thermal maturation process involving stereo controlling additives. The new carbons are expected to have outstanding flexibility and strength and novel thermal and electrical properties. The new products could give Australia a lead in new battery, hydrogen storage, flat screen technology and nanoelectronics.Read moreRead less
The role of bush fires in the formation and fate of dioxin like chemicals in Australia. A global (POPs) treaty signed by more than 100 nations targets the reduction and elimination of dioxins, which are persistent, bioaccumlative and highly toxic to humans. Bushfires have been suggested as the major source of dioxins in Australia. Experimental data indicate bushfires may not represent the actual sources of dioxin. Our aim is to experimentally establish the levels of dioxins formed and re-emi ....The role of bush fires in the formation and fate of dioxin like chemicals in Australia. A global (POPs) treaty signed by more than 100 nations targets the reduction and elimination of dioxins, which are persistent, bioaccumlative and highly toxic to humans. Bushfires have been suggested as the major source of dioxins in Australia. Experimental data indicate bushfires may not represent the actual sources of dioxin. Our aim is to experimentally establish the levels of dioxins formed and re-emitted from bushfires in Australia. The results will assist to make informed decisions that lead to effective action for reducing dioxin contamination in Australia, fulfilling the treaty requirements and protecting the population and environment.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0239647
Funder
Australian Research Council
Funding Amount
$290,000.00
Summary
Infrared chemical imaging and high temperature emission spectroscopy facility. Infrared spectroscopic imaging uses infrared radiation to analyse the chemical properties of microscopic samples in a fast and powerful manner. The images produced provide information about the different molecular chemistry at each pixel in the image. This is one of the latest and perhaps most important developments in vibrational spectroscopy, with wide applications in materials science, forensic science and the biol ....Infrared chemical imaging and high temperature emission spectroscopy facility. Infrared spectroscopic imaging uses infrared radiation to analyse the chemical properties of microscopic samples in a fast and powerful manner. The images produced provide information about the different molecular chemistry at each pixel in the image. This is one of the latest and perhaps most important developments in vibrational spectroscopy, with wide applications in materials science, forensic science and the biological sciences. It is an exceptional tool for the analysis of heterogeneous solids, whether these be seized drug samples, cancer cells, fibres left at a crime scene, layers of paint from a car or a Monet painting, or polymer blends.Read moreRead less
Reactions of Coordinated Dinitrogen. The program will develop novel metal-based catalysts and reagents that will transform nitrogen gas into ammonia and other nitrogen-containing compounds (nitrogen fixation). This fundamental chemical transformation underpins major chemical industries and this new approach using organometallic catalysts will significantly improve the efficiency of ammonia production and reduce the energy and harsh reaction conditions currently required. This program will desi ....Reactions of Coordinated Dinitrogen. The program will develop novel metal-based catalysts and reagents that will transform nitrogen gas into ammonia and other nitrogen-containing compounds (nitrogen fixation). This fundamental chemical transformation underpins major chemical industries and this new approach using organometallic catalysts will significantly improve the efficiency of ammonia production and reduce the energy and harsh reaction conditions currently required. This program will design catalysts with multiple complementary metal centres tailored to bind and activate nitrogen gas to facilitate its reaction with hydrogen or other reagents.Read moreRead less
Designer Surfactants for Creation of Emulsion Properties. We propose new approaches to the design of surfactants for stabilising water in oil emulsions. New block copolymer surfactants may be "tailored" for head group structure and a pre-chosen hydrophilic/lipophilic balance at the oil-water interface using the Australian developed RAFT polymer synthesis method and polymeric inorganic species. The proposers have an extensive background in these areas.
X-ray and neutron scattering techniques, de ....Designer Surfactants for Creation of Emulsion Properties. We propose new approaches to the design of surfactants for stabilising water in oil emulsions. New block copolymer surfactants may be "tailored" for head group structure and a pre-chosen hydrophilic/lipophilic balance at the oil-water interface using the Australian developed RAFT polymer synthesis method and polymeric inorganic species. The proposers have an extensive background in these areas.
X-ray and neutron scattering techniques, developed by us, allow the interfacial structure of the surfactant to be found and the intellectual "loop" closed in the design process. Preliminary screening will be done using the surface balance and bulk emulsion synthesis.Read moreRead less
Atmospheric fate and processes of semi-volatile organic compounds in tropical climates. The outcomes from this study will contribute fundamental and quantitative information for evaluation of the fate of semi-volatile organic compounds (SOCs) in tropical systems, including Australia's World Heritage ecosystems such as rainforest and the Great Barrier Reef. The study addresses key international knowledge gaps with respect to the influence of climate on SOC atmospheric fate. Australia's geographic ....Atmospheric fate and processes of semi-volatile organic compounds in tropical climates. The outcomes from this study will contribute fundamental and quantitative information for evaluation of the fate of semi-volatile organic compounds (SOCs) in tropical systems, including Australia's World Heritage ecosystems such as rainforest and the Great Barrier Reef. The study addresses key international knowledge gaps with respect to the influence of climate on SOC atmospheric fate. Australia's geographical location within the tropical belt provides an ideal opportunity for leading this field of research and contributes relevant data for its commitment under the Stockholm Convention.Read moreRead less
Development and Use of Ionic Liquids in Metal Recovery from Ores, Concentrates and Mattes. Ionic liquids, which are liquid over a wide temperature range and can dissolve a wide range of solutes to high concentrations, promise new and yet unexplored approaches in processing ores. We aim to prepare ionic liquids and apply these to increase the intensity of copper and gold sulfide processing, and to explore more efficient separation of platinum group metals from mattes. New oxidative leaching techn ....Development and Use of Ionic Liquids in Metal Recovery from Ores, Concentrates and Mattes. Ionic liquids, which are liquid over a wide temperature range and can dissolve a wide range of solutes to high concentrations, promise new and yet unexplored approaches in processing ores. We aim to prepare ionic liquids and apply these to increase the intensity of copper and gold sulfide processing, and to explore more efficient separation of platinum group metals from mattes. New oxidative leaching techniques will be developed to diminish ore passivation and enhance recovery; high current electrowinning of copper in ionic liquids will be probed. Evolving technology should yield economic and environmental benefits for a nationally important industry.Read moreRead less
Novel Technologies for the Purification of Recombinant Proteins. Availability of enabling technologies for the large-scale purification of recombinant proteins is an essential requirement of the biotechnology industry. This project aims to integrate two concepts in molecular biorecognition. New modalities of immobilised metal ion affinity chromatography will be linked with the selection of new types of peptide affinity handles that can be inserted by genetic engineering methods into proteins pro ....Novel Technologies for the Purification of Recombinant Proteins. Availability of enabling technologies for the large-scale purification of recombinant proteins is an essential requirement of the biotechnology industry. This project aims to integrate two concepts in molecular biorecognition. New modalities of immobilised metal ion affinity chromatography will be linked with the selection of new types of peptide affinity handles that can be inserted by genetic engineering methods into proteins produced by biotechnological procedures. The approach followed then allows these handles to be removed following isolation of the target protein. This project could thus lead to a considerable advance in the manufacture of recombinant proteins intended for human therapy.Read moreRead less