Excessive sitting and population health: strengthening the science and the relevance to policy and practice. The majority of Australian adults spend most of their waking hours sitting; this increases the likelihood of developing diseases of inactivity, including diabetes, heart disease and some cancers. New research will investigate what factors encourage excessive sitting and what the health benefits are for people who deliberately do less sitting.
Molecular and immunological approaches to managing Australia's seafood allergy epidemic. Seafood is an increasingly important cause of food allergy. Novel insight into the functions of why and how proteins from seafood develop to potent allergens will lead to the development of better diagnostics and therapeutics. This will assist patients to better manage their serious food allergy.
Agreements as a mechanism for community participation in health policy: Understanding process and evaluating effectiveness. Improving the health of Indigenous people requires health policy that is inclusive and proactive rather than crisis driven. Formal agreements outline responsibilities and accountabilities in a shared framework that respects the rights of the parties involved. This project will evaluate the quality and effectiveness of agreements in Indigenous health by assessing their abil ....Agreements as a mechanism for community participation in health policy: Understanding process and evaluating effectiveness. Improving the health of Indigenous people requires health policy that is inclusive and proactive rather than crisis driven. Formal agreements outline responsibilities and accountabilities in a shared framework that respects the rights of the parties involved. This project will evaluate the quality and effectiveness of agreements in Indigenous health by assessing their ability to change the way governments and communities work together to improve health. The project will help ensure that future agreements reflect shared solutions for improving the health of Indigenous people in a respectful and effective way. It will also determine whether agreements work to bring community and government together to reduce inequalities in health.Read moreRead less
Development of new interventions and treatment for schistosomiasis morbidity control. Australia has played a lead role in Parasitology research. It is vital to remain at the forefront in combating the human and livestock diseases that parasites cause. Vaccine assessment and the large scale analysis of patient tissues are vital to the biotechnology, agriculture and pharmaceutical industries with outcomes leading to innovative strategies for control. Politically there is value as it is altruistic ....Development of new interventions and treatment for schistosomiasis morbidity control. Australia has played a lead role in Parasitology research. It is vital to remain at the forefront in combating the human and livestock diseases that parasites cause. Vaccine assessment and the large scale analysis of patient tissues are vital to the biotechnology, agriculture and pharmaceutical industries with outcomes leading to innovative strategies for control. Politically there is value as it is altruistic to develop new tools, technologies and treatments for the Asia/Pacific region. Economically, Australia will have first pass at developing the intellectual property arising. As well, the therapies would be developed locally to the benefit of Australia's human therapeutics industry and bio-reagent manufacturers.Read moreRead less
Better prevention and management of disabling back pain. This project will establish a program of back pain research within an inter-disciplinary research centre focused on the prevention and management of physical disability.
From risk factor analysis to translation: multiple sclerosis and vitamin D deficiency. This research on multiple sclerosis will focus on its causes and lifestyle factors that affect it and will trial vitamin D supplementation as a treatment. Studies on vitamin D deficiency in healthy populations aim to develop new public health recommendations on sun exposure and vitamin D that balance risk of skin cancer against vitamin D deficiency.
Assessing the social and environmental determinants of seasonal influenza outbreaks. This project aims to examine the potential social and environmental predictors of seasonal influenza outbreaks across temperate and tropical climates. It will develop a spatiotemporal model to identify where, when and who is most susceptible to changes of risk in influenza epidemic-prone regions of Queensland, Australia and Gansu province and Shanghai City, China. A spatiotemporal predictive model for influenza ....Assessing the social and environmental determinants of seasonal influenza outbreaks. This project aims to examine the potential social and environmental predictors of seasonal influenza outbreaks across temperate and tropical climates. It will develop a spatiotemporal model to identify where, when and who is most susceptible to changes of risk in influenza epidemic-prone regions of Queensland, Australia and Gansu province and Shanghai City, China. A spatiotemporal predictive model for influenza will be useful for the early identification of impending epidemics, which will lead to a more rapid and efficiently targeted response than is possible with the current system, thereby reducing the magnitude and health and economic impact of epidemics.Read moreRead less
Improving Outcome after Stroke through Earlier Rehabilitation: The Very Early Rehabilitation Research Program. Stroke presents a major, growing global public health challenge accounting for 25% of all chronic disability. Treatments that reduce the burden of stroke are urgently needed, and early rehabilitation may significantly reduce chronic disability. A large, high quality, National Health and Medical Research Council funded clinical trial is at the heart of the A Very Early Rehabilitation Tri ....Improving Outcome after Stroke through Earlier Rehabilitation: The Very Early Rehabilitation Research Program. Stroke presents a major, growing global public health challenge accounting for 25% of all chronic disability. Treatments that reduce the burden of stroke are urgently needed, and early rehabilitation may significantly reduce chronic disability. A large, high quality, National Health and Medical Research Council funded clinical trial is at the heart of the A Very Early Rehabilitation Trial (AVERT) program. The trial tests whether a simple, rehabilitation intervention (early and intensive out of bed activity) results in fewer deaths and less disability for stroke sufferers and is cost effective. If effective the intervention could be adopted across different health services both here and overseas, reducing the global burden of stroke.Read moreRead less
Urban spaces and active ageing: understanding person-environment interactions to inform activity-friendly community design. The proportion of older adults in urban areas is rapidly growing, leading to increases in health-care costs that are associated with chronic diseases. This can be offset by creating urban environments that support an active lifestyle across mid-to-late adulthood. How urban community designs shape the physical activity of this understudied age group is unclear. Using a suite ....Urban spaces and active ageing: understanding person-environment interactions to inform activity-friendly community design. The proportion of older adults in urban areas is rapidly growing, leading to increases in health-care costs that are associated with chronic diseases. This can be offset by creating urban environments that support an active lifestyle across mid-to-late adulthood. How urban community designs shape the physical activity of this understudied age group is unclear. Using a suite of national and international epidemiological studies, This project aims to identify the optimal mix and spatial distribution of destinations (facilities and places to visit) for active ageing, while taking into account factors that define one’s ability and willingness to visit these destinations. This will inform public policy and activity-friendly community design.Read moreRead less
Translational research in osteoarthritis: from epidemiological studies to clinical interventions. Currently the only treatment for osteoarthritis is to relieve pain. However, there are some factors that may affect the progression of this disease. This project will examine these factors including inflammation, metabolism, and physical inactivity, and find potential modifying therapies such as vitamin D supplementation for osteoarthritis.