The pharmacokinetics of plant secondary metabolites and their effects on feeding in the brushtail possum. Plant secondary metabolites (PSMs) are considered to protect against herbivory, although the mechanisms are not well understood. This project will determine how marsupial folivores avoid toxicity when browsing on Eucalyptus leaf. Blood levels of terpenes, phenols and their metabolites will be measured in the brushtail possum while it feeds on a diet of varying PSM content. We expect to be ab ....The pharmacokinetics of plant secondary metabolites and their effects on feeding in the brushtail possum. Plant secondary metabolites (PSMs) are considered to protect against herbivory, although the mechanisms are not well understood. This project will determine how marsupial folivores avoid toxicity when browsing on Eucalyptus leaf. Blood levels of terpenes, phenols and their metabolites will be measured in the brushtail possum while it feeds on a diet of varying PSM content. We expect to be able to show relationships between the ingestion and blood levels of PSMs and feeding behaviour. This will give a greater understanding of the effect of plant toxins on browsing behaviour, enabling improved foraging models and more effective habitat management.Read moreRead less
Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia ....Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia from invasive diseases. There is an urgency to undertake our research because global environmental change and increasing movements of people (particularly military personnel) from overseas regions where these diseases are endemic is increasing the vulnerability of northern Australia to the (re)establishment of mosquito borne diseases.Read moreRead less
Managing Tasmanian devil populations affected by the Devil Facial Tumour Disease. This project aims to put the science behind management options for wild Tasmanian devil populations affected by the Devil Facial Tumour Disease (DFTD), a new emerging wildlife disease that is decimating devil populations across large parts of Tasmania. DFTD behaves atypically compared with well-studied wildlife disease models; this project may result in important breakthroughs in our understanding of wildlife disea ....Managing Tasmanian devil populations affected by the Devil Facial Tumour Disease. This project aims to put the science behind management options for wild Tasmanian devil populations affected by the Devil Facial Tumour Disease (DFTD), a new emerging wildlife disease that is decimating devil populations across large parts of Tasmania. DFTD behaves atypically compared with well-studied wildlife disease models; this project may result in important breakthroughs in our understanding of wildlife diseases. Conservation outcomes of the project may slow the spread of the disease and in aiding population recovery. Devils are an iconic species with economic benefits for ecotourism and livestock farms, industries which are based in economically depressed rural regions.Read moreRead less