Children and Adolescents with Type 1 Diabetes: Determining Critical Pathways to Self-Management. Poor management of Type 1 diabetes during childhood and adolescence can have devastating consequences for the individual's health and quality of life making it a national research priority. By identifying the paths to self-management more effective interventions, tailored to the individual's personal and family circumstances and geographical location can be recommended. This will not only give childr ....Children and Adolescents with Type 1 Diabetes: Determining Critical Pathways to Self-Management. Poor management of Type 1 diabetes during childhood and adolescence can have devastating consequences for the individual's health and quality of life making it a national research priority. By identifying the paths to self-management more effective interventions, tailored to the individual's personal and family circumstances and geographical location can be recommended. This will not only give children with diabetes a healthy start to life but promote their health and well-being as adults. Such benefits are not just to individuals and their families but to Australian society through their increased independence and productivity and the reduced burden on the health system.Read moreRead less
The effect of age on regulatory T cell control of the innate and adaptive antiviral immune responses. Viral pathogens are a lead cause of infant mortality in the world. This project will define how T regulatory cells limit protective antiviral immune responses in the young. This information is critical for the development of potent antiviral vaccines that are effective from the newborn period without inducing autoimmunity. It will also provide novel insight into the way T regulatory cells can b ....The effect of age on regulatory T cell control of the innate and adaptive antiviral immune responses. Viral pathogens are a lead cause of infant mortality in the world. This project will define how T regulatory cells limit protective antiviral immune responses in the young. This information is critical for the development of potent antiviral vaccines that are effective from the newborn period without inducing autoimmunity. It will also provide novel insight into the way T regulatory cells can be manipulated both to dampen immunity, which can be used to develop strategies to reduce immune mediated disease and limit transplant rejection. Read moreRead less
Knowing in advance: Effective strategies for preparing young children for novel experiences. To optimise cognitive and emotional development, it is critical to identify the influences on children's lives. How parent-child conversations about the past shape development is well understood, but scant research has examined how adult-child preparatory discussions influence children's experience and memory of future events. Our research addresses this gap. It has important implications in medical, edu ....Knowing in advance: Effective strategies for preparing young children for novel experiences. To optimise cognitive and emotional development, it is critical to identify the influences on children's lives. How parent-child conversations about the past shape development is well understood, but scant research has examined how adult-child preparatory discussions influence children's experience and memory of future events. Our research addresses this gap. It has important implications in medical, educational, and other contexts in which it is vital to ensure that information given in advance increases children's understanding of an experience. More generally, in specifying optimal parent-child interactions, the findings are also relevant to interventions aiming to enhance psychological and emotional resilience in the early years. Read moreRead less
Foot-down not ground-up: moving from splint to natural models for children's shoe design. We will provide much-needed knowledge of the impact of children's footwear on their musculoskeletal development, by conducting rigorous experimental comparisons of a standard school shoe, a custom-built 'midfoot flexing' shoe, bare feet, and a new school shoe design concept developed by university researchers to enhance rather than disrupt natural foot function. The innovation will make Bata Australia the f ....Foot-down not ground-up: moving from splint to natural models for children's shoe design. We will provide much-needed knowledge of the impact of children's footwear on their musculoskeletal development, by conducting rigorous experimental comparisons of a standard school shoe, a custom-built 'midfoot flexing' shoe, bare feet, and a new school shoe design concept developed by university researchers to enhance rather than disrupt natural foot function. The innovation will make Bata Australia the first manufacturer to embrace evidence-based shoe design, and will be an opportunity for the Company to provide global leadership in the field. Our advances will inform health professionals, manufacturers and parents in the task of improving the musculoskeletal health of young Australians.Read moreRead less
Effectiveness of social skills training for children with autism. Our industry partner, Aspect Australia, is one of the world's largest providers of educational and other services for people with autism. The demonstration of effectiveness of the program in Aspect classes will likely lead to widespread use and benefit of the program in the education sector nationally and internationally. This in turn would lead to potential lessening of disability in children with autism with improvements in thei ....Effectiveness of social skills training for children with autism. Our industry partner, Aspect Australia, is one of the world's largest providers of educational and other services for people with autism. The demonstration of effectiveness of the program in Aspect classes will likely lead to widespread use and benefit of the program in the education sector nationally and internationally. This in turn would lead to potential lessening of disability in children with autism with improvements in their mental health and significant cost savings to the community.Read moreRead less
Parasite virulence: the role of activation and suppression of P2X7 receptors. Toxoplasmosis and leishmaniasis pose a threat to the health and well-being of the Australian human and animal populations. Around 6-8 million Australians are infected with Toxoplasma, a parasite that can cause severe problems in immunosuppressed individuals and birth defects and miscarriage in pregnant women with a primary infection. Toxoplasmosis is also the main cause of abortion and stillbirth in Australian sheep. L ....Parasite virulence: the role of activation and suppression of P2X7 receptors. Toxoplasmosis and leishmaniasis pose a threat to the health and well-being of the Australian human and animal populations. Around 6-8 million Australians are infected with Toxoplasma, a parasite that can cause severe problems in immunosuppressed individuals and birth defects and miscarriage in pregnant women with a primary infection. Toxoplasmosis is also the main cause of abortion and stillbirth in Australian sheep. Leishmaniasis, recently found in Australia, is a risk for overseas travellers, livestock and wildlife. This research will provide an understanding of what makes these parasites successful, paving the way for development of novel drugs to combat these chronic diseases.Read moreRead less
Metal emissions from petrol and the future health of children. We aim to determine the contribution of manganese, lead, and other metal emissions from motor vehicles to the environment and exposure of
children. Manganese is of potential concern because of (a) its recent
introduction as methylcyclopentadienyl manganese tricarbonyl (MMT) in
Australia as a fuel additive to replace lead and (b) the lack of information on environmental levels, exposure, and long-term health effects, especially in ....Metal emissions from petrol and the future health of children. We aim to determine the contribution of manganese, lead, and other metal emissions from motor vehicles to the environment and exposure of
children. Manganese is of potential concern because of (a) its recent
introduction as methylcyclopentadienyl manganese tricarbonyl (MMT) in
Australia as a fuel additive to replace lead and (b) the lack of information on environmental levels, exposure, and long-term health effects, especially in children. This project conforms with a Designated National Research Priority and is a collaborative project bringing together researchers from academia, CSIRO, industry, and the US.
Environmental Protection Agency.
Read moreRead less
Engaging economically disadvantaged adolescent girls in physical activity and healthy eating to improve health and prevent obesity. Secondary school represents the final opportunity to influence individuals as they develop adult lifestyle behaviours and enter a transitional period in their lives. Considering the increased prevalence of lifestyle diseases among Australian adults and increases in the prevalence of obesity among young Australians, targeting health-promoting behaviours in adolescent ....Engaging economically disadvantaged adolescent girls in physical activity and healthy eating to improve health and prevent obesity. Secondary school represents the final opportunity to influence individuals as they develop adult lifestyle behaviours and enter a transitional period in their lives. Considering the increased prevalence of lifestyle diseases among Australian adults and increases in the prevalence of obesity among young Australians, targeting health-promoting behaviours in adolescents is clearly a national priority. Furthermore, rates of obesity are much higher in economically disadvantaged areas, with girls more susceptible to the SES disadvantages. This project has the potential to develop a knowledge base and improve the health behaviours of current and future Australians most at risk for the development of lifestyle diseases.Read moreRead less
Special Research Initiatives - Grant ID: SR0354698
Funder
Australian Research Council
Funding Amount
$40,000.00
Summary
Future Generation: New Knowledge for Better Outcomes for Children and Young People. Australia is a prosperous country, yet over recent decades many indices of the health and wellbeing of children and young people have deteriorated. Reasons for this are not well understood, and the nation is poorly equipped to devise effective, sustainable responses. Our vision is to create new ways of thinking and acting through new collaborations across disciplines, sectors and levels of government, with non-re ....Future Generation: New Knowledge for Better Outcomes for Children and Young People. Australia is a prosperous country, yet over recent decades many indices of the health and wellbeing of children and young people have deteriorated. Reasons for this are not well understood, and the nation is poorly equipped to devise effective, sustainable responses. Our vision is to create new ways of thinking and acting through new collaborations across disciplines, sectors and levels of government, with non-research communities of interest as full partners. The aim is to generate and apply new concepts and forms of knowledge, undergirded by comprehensive, better integrated data. Expected outcomes are enriched life chances for children and young people.Read moreRead less
SPECTRAL TILT: DO INFANTS KNOW WHAT'S GOOD FOR THEM? This project falls within the National Research Priorities, giving children 'a healthy start to life'. The research is important economically because it will lay the groundwork for the informed design of hearing aid frequency responses based on empirical research, and give infants the opportunity to be fitted with hearing aids amplified for infants, not adults as is the current unsatisfactory practice. Moreover, the cross fertilisation of meth ....SPECTRAL TILT: DO INFANTS KNOW WHAT'S GOOD FOR THEM? This project falls within the National Research Priorities, giving children 'a healthy start to life'. The research is important economically because it will lay the groundwork for the informed design of hearing aid frequency responses based on empirical research, and give infants the opportunity to be fitted with hearing aids amplified for infants, not adults as is the current unsatisfactory practice. Moreover, the cross fertilisation of methods and knowledge that the collaborators bring to this grant should provide outcomes that will help maintain attention on Australia as a site of cutting edge research into hearing impairment, hearing aid development and use.Read moreRead less