Discovery Early Career Researcher Award - Grant ID: DE210101808
Funder
Australian Research Council
Funding Amount
$395,775.00
Summary
Genetic Programming for Big Data Analytics. The project aims to extend a powerful machine learning method, called genetic programming and also developing a new concept called Alpha program, for big data analytics. This project expects to generate a new approach by finding a systematic approach to develop gene structures using information theory. By borrowing the best genes from the population of programs, the Alpha program concept will be developed for the first time. The proposed approach aims ....Genetic Programming for Big Data Analytics. The project aims to extend a powerful machine learning method, called genetic programming and also developing a new concept called Alpha program, for big data analytics. This project expects to generate a new approach by finding a systematic approach to develop gene structures using information theory. By borrowing the best genes from the population of programs, the Alpha program concept will be developed for the first time. The proposed approach aims to enhance genetic programming for many practical problems. I contend that not only finding better tools for big data analytics is in the best interest of machine learning and big data communities, it also provides significant benefits for other communities and industries in Australia.Read moreRead less
Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most importa ....Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most important mechano-sensor implicated in cell adhesion, migration, growth and survival. Specifically, it integrates nationally unique cutting-edge techniques including single-molecule force probe, microparticle image velocimetry, microfluidics and molecular dynamics simulation, super resolution and 3D volumetric imaging modalities.Read moreRead less
Portable instrument for quantification and genotyping of Cryptosporidium . Cryptosporidium is a parasitic protozoan, causing more than 48,000 deaths in children under 5 and 7.2 million disability-adjusted-life-years globally. A low-cost device that rapidly detects the parasite in drinking and recreational water is needed to enable effective disease management practices. Partnering with Advanced Universal Diagnotik, Seqwater, ALS Water and Gold Coast Water, this project aims to develop a novel de ....Portable instrument for quantification and genotyping of Cryptosporidium . Cryptosporidium is a parasitic protozoan, causing more than 48,000 deaths in children under 5 and 7.2 million disability-adjusted-life-years globally. A low-cost device that rapidly detects the parasite in drinking and recreational water is needed to enable effective disease management practices. Partnering with Advanced Universal Diagnotik, Seqwater, ALS Water and Gold Coast Water, this project aims to develop a novel device, comprising advanced microfluidics and biosensing technology for parasite quantification, genotyping and viability analysis. Expected outcomes are improved Cryptosporidium management, risk prediction, and rapid mitigation of impending outbreaks. The proposed platform has a great potential for detecting other pathogens.Read moreRead less
Controllable synthesis of multifunctional boron-based 2D materials. This project aims to make it possible to control the synthesis of boron-based two-dimensional (2D) materials with the desired following features in single or multiple aspects: thickness, composition, lateral sizes, porosity, surface area, and functionality. It intends to do so by designing and synthesising novel precursors, and by optimising the fabrication process of boron-based 2D nanosheets for different applications. The pro ....Controllable synthesis of multifunctional boron-based 2D materials. This project aims to make it possible to control the synthesis of boron-based two-dimensional (2D) materials with the desired following features in single or multiple aspects: thickness, composition, lateral sizes, porosity, surface area, and functionality. It intends to do so by designing and synthesising novel precursors, and by optimising the fabrication process of boron-based 2D nanosheets for different applications. The project will advance our fundamental knowledge in synthetic chemistry, materials chemistry, materials engineering and physics. It is expected to take us closer to unlocking the potential of boron-based 2D materials for real-world applications in, for example, energy storage and high-performance flexible electronics.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100019
Funder
Australian Research Council
Funding Amount
$408,000.00
Summary
A Scalable and Adaptive-Resilient Blockchain. This project aims to address the security and scalability challenges that limit blockchain adoption. Existing blockchains do not scale and are vulnerable to attacks (e.g. with a total loss of over US$1 billion in 2019). This project expects to improve security by adaptively enforcing the currently broken security assumptions, and to improve scalability by designing blockchains with high concurrency via relaxed criteria on the ordering of transactions ....A Scalable and Adaptive-Resilient Blockchain. This project aims to address the security and scalability challenges that limit blockchain adoption. Existing blockchains do not scale and are vulnerable to attacks (e.g. with a total loss of over US$1 billion in 2019). This project expects to improve security by adaptively enforcing the currently broken security assumptions, and to improve scalability by designing blockchains with high concurrency via relaxed criteria on the ordering of transactions. The expected outcomes include foundations and practical solutions for self-adaptive, secure and scalable blockchains. The benefits of this would be improved confidence in and capacity for building blockchain applications, which have a predicted value of over US$3.1 trillion by 2030.Read moreRead less
Superconducting silicon nanodevices. This project will investigate superconductivity in silicon nanowire devices exhibiting both p-type and n-type conductivity. It builds on the recent demonstration at the University of Melbourne of superconductivity in nanowire devices at length-scales suitable for realisation of a broad range of superconducting device structures and utilises standard semiconductor-industry processes. This project will create a new platform for superconducting device developmen ....Superconducting silicon nanodevices. This project will investigate superconductivity in silicon nanowire devices exhibiting both p-type and n-type conductivity. It builds on the recent demonstration at the University of Melbourne of superconductivity in nanowire devices at length-scales suitable for realisation of a broad range of superconducting device structures and utilises standard semiconductor-industry processes. This project will create a new platform for superconducting device development in silicon with potential for building devices with new functionality and improved performance for applications in quantum information technologies, enhancing Australia’s global reputation in quantum information science and assisting emerging industries in this high-valued added area.Read moreRead less
Cost-efficient 2D heterostructures for solar overall water splitting. This project aims to develop novel processes to enable water splitting to generate hydrogen and oxygen under sunlight using cost-efficient 2D van der Waals heterostructures. Enhanced optical absorption and reduced charge transfer distance across the interface are expected to improve the photocatalytic activity. Experimental design and theoretical simulations will be combined to modulate the materials and achieve optimum photoc ....Cost-efficient 2D heterostructures for solar overall water splitting. This project aims to develop novel processes to enable water splitting to generate hydrogen and oxygen under sunlight using cost-efficient 2D van der Waals heterostructures. Enhanced optical absorption and reduced charge transfer distance across the interface are expected to improve the photocatalytic activity. Experimental design and theoretical simulations will be combined to modulate the materials and achieve optimum photocatalytic performances. Expected outcomes of this project include expanded chemistry knowledge and techniques in materials design and synthesis, photophysics and photocatalysis mechanism and solar energy conversion. This will provide significant benefits to clean energy and environmental protections.Read moreRead less
A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interac ....A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interactions, which will greatly complement existing meta-omics approaches. The deliverables include a proof-of-concept system validated for gut-liver axis as well as the creation of new knowledge and framework to assimilate design thinking and advanced manufacturing to elevate tissue engineering into physiology engineering. Read moreRead less
Augmented Sociality: Enabling a Socialised Experience of Augmented Reality. This project will explore new socialised uses of Augmented Reality (AR) that expand creativity, social relations, and participation. We seek to better understand how AR content can be leveraged by people to create their own new ways of learning, collaborating, and relating with each other. To do so we will study and prototype new tools and platforms to allow non-experts to create their own AR media. We aim to enable peop ....Augmented Sociality: Enabling a Socialised Experience of Augmented Reality. This project will explore new socialised uses of Augmented Reality (AR) that expand creativity, social relations, and participation. We seek to better understand how AR content can be leveraged by people to create their own new ways of learning, collaborating, and relating with each other. To do so we will study and prototype new tools and platforms to allow non-experts to create their own AR media. We aim to enable people of all ages, education, and background, to imagine and create, and not just passively consume, AR contents, services, and applications. We will generate new applications of AR, a new platform to collaboratively create these applications, and a new theory of 'Augmented Sociality' to guide AR design.
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Enabling Situated Immersive Science Collaboration with Remote Sensing Data . This project aims to help scientists communicate and collaborate in immersive environments. Fieldwork is more valuable to scientists than looking at abstract remote data, but expense, danger, or inaccessible locations often stand in the way. This project will address this issue by researching and designing immersive environments that combine remote data with visualisations and new interaction tools for science teams to ....Enabling Situated Immersive Science Collaboration with Remote Sensing Data . This project aims to help scientists communicate and collaborate in immersive environments. Fieldwork is more valuable to scientists than looking at abstract remote data, but expense, danger, or inaccessible locations often stand in the way. This project will address this issue by researching and designing immersive environments that combine remote data with visualisations and new interaction tools for science teams to make sense of spatial and temporal aspects of data. Outcomes will include new presentation and interaction methods, an evaluation with geoscientists, and a framework for designing interactive systems that enable situated interactions. Benefits will include helping Australian scientists overcome distance in their research. Read moreRead less