Special Research Initiatives - Grant ID: SR0566756
Funder
Australian Research Council
Funding Amount
$95,254.00
Summary
Application for funding to develop a software grid for data-sharing associated with the NISAD/LONI Virtual Brain Bank. This project will produce tools to enhance collaboration between researchers at physically disparate locations. It builds on emerging Grid computer network technology to create virtual research communities that permit secure sharing of geographically disjoint resources such as data collections, computer software and computer processing power. The project’s test case will creat ....Application for funding to develop a software grid for data-sharing associated with the NISAD/LONI Virtual Brain Bank. This project will produce tools to enhance collaboration between researchers at physically disparate locations. It builds on emerging Grid computer network technology to create virtual research communities that permit secure sharing of geographically disjoint resources such as data collections, computer software and computer processing power. The project’s test case will create a community of researchers into brain disease (e.g. schizophrenia) who are located in three Australian and one USA site and who will share their patient data, analysis tools and special-purpose computer equipment. The developed tools will allow relatively simple and rapid deployment of similar research grids suitable for a wide range of collaborative projects.Read moreRead less
Imaging genetics in schizophrenia and bipolar disorder: shared neurocognitive endophenotypes. Combined, schizophrenia and bipolar disorder afflict approximately 506,000 Australians at any one time, and are leading causes of disability and national economic burden. This study will delineate genetic underpinnings for these conditions in association with specific neurocognitive dysfunctions that are common to both disorders. These findings have important implications for the implementation of perso ....Imaging genetics in schizophrenia and bipolar disorder: shared neurocognitive endophenotypes. Combined, schizophrenia and bipolar disorder afflict approximately 506,000 Australians at any one time, and are leading causes of disability and national economic burden. This study will delineate genetic underpinnings for these conditions in association with specific neurocognitive dysfunctions that are common to both disorders. These findings have important implications for the implementation of personalised pharmaceutical treatments on the basis of genotype, and the development of therapeutic agents to target cognitive function. These results will also aid detection of premorbid psychotic illness in young individuals who may benefit from early intervention that may thwart the illness trajectory. Read moreRead less
Computational methods for precise reconstruction of white-matter fibre tracts in the human brain using diffusion tensor imaging. One in five Australians will experience a mental illness. This project will facilitate a new method for: (1) brain researchers to advance the fundamental understanding of mental illnesses and brain disorders; (2) medical clinicians to diagnose and assess the growing incidence of mental illness confronting Australia's ageing population, thereby addressing the ageing wel ....Computational methods for precise reconstruction of white-matter fibre tracts in the human brain using diffusion tensor imaging. One in five Australians will experience a mental illness. This project will facilitate a new method for: (1) brain researchers to advance the fundamental understanding of mental illnesses and brain disorders; (2) medical clinicians to diagnose and assess the growing incidence of mental illness confronting Australia's ageing population, thereby addressing the ageing well and ageing productively national research priority; and, (3) neurosurgeons to guide surgery via localisation of major neural tracts. In addition to contributing to the understanding, diagnosis and treatment of Australia's endemic mental health burden, this project will advance Australia's skill-base and international standing in basic scientific research.Read moreRead less
Charting connectivity in the healthy and diseased brain. Australia's endemic mental health burden is predicted to escalate as its population ages. This project will: (1) endow medicine with a diagnostic capability enabling earlier and more-accurate diagnosis of brain disorders and mental illnesses; and, (2) pinpoint brain circuit disruptions telltale of particular diseases. This is a world-first and promises a scientific basis for new-generation therapies and treatments. This project will enable ....Charting connectivity in the healthy and diseased brain. Australia's endemic mental health burden is predicted to escalate as its population ages. This project will: (1) endow medicine with a diagnostic capability enabling earlier and more-accurate diagnosis of brain disorders and mental illnesses; and, (2) pinpoint brain circuit disruptions telltale of particular diseases. This is a world-first and promises a scientific basis for new-generation therapies and treatments. This project will enable the APD to disseminate the specialist knowledge acquired as an ARC Fellow at Harvard in 2008 to Australian researchers, thereby advancing Australia's international standing in science.Read moreRead less
Enhancing Hypnotic Responding with Oxytocin. Although hypnosis has been studied for over a 100 years, little is understood about the neuroscience of hypnosis. This project represents the first investigation of the neural mechanisms underpinning hypnosis. At an applied level, this project has the potential to markedly increase the capacity for Australians to benefit from medical and psychological hypnosis. Hypnosis has been shown to assist in many medical and psychological conditions, and by d ....Enhancing Hypnotic Responding with Oxytocin. Although hypnosis has been studied for over a 100 years, little is understood about the neuroscience of hypnosis. This project represents the first investigation of the neural mechanisms underpinning hypnosis. At an applied level, this project has the potential to markedly increase the capacity for Australians to benefit from medical and psychological hypnosis. Hypnosis has been shown to assist in many medical and psychological conditions, and by developing the means to increase hypnotic responding, this project can directly enhance the physical and psychological health of Australians.Read moreRead less