Intergenerational transmission of dietary behaviour. The health of future generations depends largely on the health of current generations. Bad eating habits associated with obesity and other chronic diseases are often passed from parents to children. This study will provide insight into the ways in which these habits are perpetuated within families of various cultural backgrounds. It will establish how assessing family health history can be used as a tool to help identify and modify the risk of ....Intergenerational transmission of dietary behaviour. The health of future generations depends largely on the health of current generations. Bad eating habits associated with obesity and other chronic diseases are often passed from parents to children. This study will provide insight into the ways in which these habits are perpetuated within families of various cultural backgrounds. It will establish how assessing family health history can be used as a tool to help identify and modify the risk of chronic, life-threatening disease in families and individuals. If proven effective, this tool can be rolled out nationwide to help promote and maintain healthier diets in Australian families and reduce the economic burden on the government.Read moreRead less
Post-implementation economic evaluation of childhood vaccination programs. This project will develop a novel framework for assessing the value for money achieved by childhood vaccination programs. This will provide decision makers with methodologically sound economic assessments that incorporate real world program outcomes.
Development of dense gas technology platforms for the formulation of oral vaccines. This project will aim to develop a technology platform that enables the formulation of vaccines that can be delivered orally and this research has the potential to radically change existing vaccination regimens. The availability of needle-free vaccination also has potential for considerable societal and economic impact in developing countries.
Understanding heat shock protein complex vaccines. This project aims to understand the mechanism of action and formulation requirements of a novel vaccine technology that utilises heat shock protein complexes. By understanding how this technology works, future vaccines can be improved to induce the immune response required to target specific pathogens, as well as give assurance regarding its safety.
Highly multiplexed rapid-analysis microarrays for early disease diagnosis. Molecular diagnostics are revolutionising the treatment of disease in hospitals by providing rapid and accurate identification of pathogens; saving costs, time and lives. This project will accelerate this revolution by combining new array technology from the University of Sydney with a proven multiplex method from the Sydney based company, AusDiagnostics.
The effect of a practice change intervention in increasing, on a network-wide basis, the provision of preventive care by community health clinicians. Community health services do not routinely deliver care that aims to decrease client health risk behaviours. The effectiveness of an intervention designed to enhance the delivery of such care will be examined.
Enhancing health literacy to optimise health equality across Victorian communities. Health literacy—the ability to seek, understand and use health information—is a major influence on equitable health outcomes for Australians. This project will take a fresh approach to health literacy to understand vulnerable members of our community and develop supports and interventions that aim to assist services to reduce health inequalities.
Cluster randomised controlled trial of a psycho-educational intervention for people with a family history of depression for use in general practice. Many individuals with a family history of depression are concerned about their personal risk for depression. This project will develop and evaluate the first online psycho-educational intervention nationally and internationally targeted to individuals with a family history of depression for use in the general practice setting.
A mental health "thermometer" to monitor and prevent adverse treatment outcomes and self-harm among psychiatric inpatients. Our project stands to prevent adverse outcomes in psychiatric patients. An estimated 660 000 people are admitted to psychiatric hospitals each year; 99 000 of these people are worse off following treatment (assuming a deterioration rate of 15 per cent). Since monitoring can halve that rate, if this project can halve the deterioration rate again, then 24 750 inpatients acr ....A mental health "thermometer" to monitor and prevent adverse treatment outcomes and self-harm among psychiatric inpatients. Our project stands to prevent adverse outcomes in psychiatric patients. An estimated 660 000 people are admitted to psychiatric hospitals each year; 99 000 of these people are worse off following treatment (assuming a deterioration rate of 15 per cent). Since monitoring can halve that rate, if this project can halve the deterioration rate again, then 24 750 inpatients across the nation would not be worse off after treatment representing an annual saving of nearly $19.2 million per annum and reduce the number of patients who fall into a cycle of admission and readmission. Further, although suicide occurs in less than one per cent of admissions, if this research is able to predict and then reduce the suicide rate by as little as 10 per cent, then 660 lives can be saved each year.Read moreRead less
Neuroimaging changes underpinning improvements in cognition in the elderly. Natural supplements are often used to improve brain and cognitive function, however, we do not know how these supplements work in the brain. Using novel brain imaging scans, the project will investigate whether 12-month administration of two promising natural supplements improves brain markers of ageing and cognitive decline in an elderly population.