Psychological strategies for maximum health and enjoyment during moderate intensity and vigorous physical exercise. This project will change the way people think during physical exercise. It will show adults of all ages and levels of experience how to get more out of moderate intensity and vigorous exercise by reducing perceived effort and making it more enjoyable.
Molecular and immunological approaches to managing Australia's seafood allergy epidemic. Seafood is an increasingly important cause of food allergy. Novel insight into the functions of why and how proteins from seafood develop to potent allergens will lead to the development of better diagnostics and therapeutics. This will assist patients to better manage their serious food allergy.
Development of dense gas technology platforms for the formulation of oral vaccines. This project will aim to develop a technology platform that enables the formulation of vaccines that can be delivered orally and this research has the potential to radically change existing vaccination regimens. The availability of needle-free vaccination also has potential for considerable societal and economic impact in developing countries.
Skin penetration of nanoparticles promoted by particle design, formulation and application method. This project seeks to better define the determinants of nanoparticle skin penetration and subsequent disposition in the body. The data would be used to guide minimal skin penetration of 'undesirable' nanoparticles and the properties required of 'safe' nanoparticles to enable effective human skin delivery in cosmetic and dermatological products.
Understanding how local and regional accessibility are associated with active travel, and related health and economic impacts. Exercise and walking are vital for a healthy lifestyle and wellbeing. The accessibility and ’walkability’ of where one lives and works is key to supporting physical activity. Consequently, public health practitioners, urban planners and the transport sector face a common strategic challenge; shifting people from private vehicles to active forms of transport. This project ....Understanding how local and regional accessibility are associated with active travel, and related health and economic impacts. Exercise and walking are vital for a healthy lifestyle and wellbeing. The accessibility and ’walkability’ of where one lives and works is key to supporting physical activity. Consequently, public health practitioners, urban planners and the transport sector face a common strategic challenge; shifting people from private vehicles to active forms of transport. This project aims to model the health and economic impacts of the ease of: walking and cycling within neighbourhoods; and travelling across wider geographical areas on time spent walking and cycling for transport among both adults and children. This project aims to enable the research team to maximise the opportunities the environment provides for both positive health and well-being in Australia.Read moreRead less
Genomic strategies for reducing losses during processing and improving the nutritional value of wheat in human diets. Wheat breeding requires efficient tools to allow selection of varieties with both high grain yield and good functional and nutritional value. Whole genome analysis will be used to develop screening methods to deliver wheat varieties with novel processing and nutritional properties for human diets contributing to global food and nutritional security.
Protecting young people from harm and injury: investigating the utility of a risk and protective framework. Serious injuries due to transport, violence and alcohol associated risk-taking are the main cause of teenage death. An innovative school course will be taught and evaluated that increases protecting others from risk, helping injured friends and promoting a connected environment where teachers and peers reach out to provide support.
Engineering electrochemical protein biosensors. This project plans to develop novel, sensitive, inexpensive and flexible electric biosensors to monitor potentially any molecule. It plans to use synthetic biology principles to develop a new class of artificial protein receptors that generate electric current upon encountering a molecular target. Using expertise in in vitro protein synthesis, the project plans to integrate biosensor design and electrode prototyping to achieve rapid development of ....Engineering electrochemical protein biosensors. This project plans to develop novel, sensitive, inexpensive and flexible electric biosensors to monitor potentially any molecule. It plans to use synthetic biology principles to develop a new class of artificial protein receptors that generate electric current upon encountering a molecular target. Using expertise in in vitro protein synthesis, the project plans to integrate biosensor design and electrode prototyping to achieve rapid development of low-cost broadly applicable sensory electrodes. To increase the sensitivity of the resulting sensing systems, the electrochemical receptors will be integrated with signal amplification cascades based on artificial autoinhibited proteases. The project aims to address the need for new technologies that enable collection of biological information outside of the laboratory environment.Read moreRead less
Assessing the social and environmental determinants of seasonal influenza outbreaks. This project aims to examine the potential social and environmental predictors of seasonal influenza outbreaks across temperate and tropical climates. It will develop a spatiotemporal model to identify where, when and who is most susceptible to changes of risk in influenza epidemic-prone regions of Queensland, Australia and Gansu province and Shanghai City, China. A spatiotemporal predictive model for influenza ....Assessing the social and environmental determinants of seasonal influenza outbreaks. This project aims to examine the potential social and environmental predictors of seasonal influenza outbreaks across temperate and tropical climates. It will develop a spatiotemporal model to identify where, when and who is most susceptible to changes of risk in influenza epidemic-prone regions of Queensland, Australia and Gansu province and Shanghai City, China. A spatiotemporal predictive model for influenza will be useful for the early identification of impending epidemics, which will lead to a more rapid and efficiently targeted response than is possible with the current system, thereby reducing the magnitude and health and economic impact of epidemics.Read moreRead less
Urban spaces and active ageing: understanding person-environment interactions to inform activity-friendly community design. The proportion of older adults in urban areas is rapidly growing, leading to increases in health-care costs that are associated with chronic diseases. This can be offset by creating urban environments that support an active lifestyle across mid-to-late adulthood. How urban community designs shape the physical activity of this understudied age group is unclear. Using a suite ....Urban spaces and active ageing: understanding person-environment interactions to inform activity-friendly community design. The proportion of older adults in urban areas is rapidly growing, leading to increases in health-care costs that are associated with chronic diseases. This can be offset by creating urban environments that support an active lifestyle across mid-to-late adulthood. How urban community designs shape the physical activity of this understudied age group is unclear. Using a suite of national and international epidemiological studies, This project aims to identify the optimal mix and spatial distribution of destinations (facilities and places to visit) for active ageing, while taking into account factors that define one’s ability and willingness to visit these destinations. This will inform public policy and activity-friendly community design.Read moreRead less