Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347945
Funder
Australian Research Council
Funding Amount
$182,000.00
Summary
Extension to Stable Isotope Facility: Elemental Analyser and GC-GC Preparative Systems. To carry out compound specific stable isotope analysis, compounds need to be resolved by GC, and with samples such as petroleum, this is uncommon. We therefore seek to explore GC-GC as a novel additional preparative system in isotope ratio mass spectrometry. Within our new State Centre of Excellence we will be confronted with samples such as soils, sediments, and natural organic matter which require examinati ....Extension to Stable Isotope Facility: Elemental Analyser and GC-GC Preparative Systems. To carry out compound specific stable isotope analysis, compounds need to be resolved by GC, and with samples such as petroleum, this is uncommon. We therefore seek to explore GC-GC as a novel additional preparative system in isotope ratio mass spectrometry. Within our new State Centre of Excellence we will be confronted with samples such as soils, sediments, and natural organic matter which require examination by bulk isotope analysis. If equipped with a customised elemental analyser as an inlet system, both our existing mass analysers will be capable of measuring carbon, hydrogen, nitrogen, oxygen and sulphur isotope values of whole samples.Read moreRead less
Detection of peptide hormone performance enhancing agents in sport using mass spectrometry. Doping control in sport is to protect the health, legal and ethical rights of athletes. The use of banned drugs in competitive sports is becoming increasingly sophisticated and the need to counter this provides a stimulus for ground breaking analytical research. This project will exploit mass spectrometry for investigation of methods to distinguish administered peptide hormones from endogenous material a ....Detection of peptide hormone performance enhancing agents in sport using mass spectrometry. Doping control in sport is to protect the health, legal and ethical rights of athletes. The use of banned drugs in competitive sports is becoming increasingly sophisticated and the need to counter this provides a stimulus for ground breaking analytical research. This project will exploit mass spectrometry for investigation of methods to distinguish administered peptide hormones from endogenous material and to develop assays for measurement of the peptide hormones, erythropoietin, growth hormone and chorionic gonadotrophin in blood or urine. The outcomes will flow to other areas where trace substance detection is important, such as environmental chemistry, medicine and quality control.Read moreRead less