A Mathematical Model of the Roles of Contraction and Oxygen in Human Wound Healing. Slow or impaired wound healing and excessive scarring associated with burns are both painful and costly. Moreover, the debilitating effect of chronic wounds can be expected to increase with the continuing aging of the population and the current rise in incidence of Type 2 diabetes. This project brings together a multidisciplinary team to develop a mathematical model of human wound healing and to drive the modelli ....A Mathematical Model of the Roles of Contraction and Oxygen in Human Wound Healing. Slow or impaired wound healing and excessive scarring associated with burns are both painful and costly. Moreover, the debilitating effect of chronic wounds can be expected to increase with the continuing aging of the population and the current rise in incidence of Type 2 diabetes. This project brings together a multidisciplinary team to develop a mathematical model of human wound healing and to drive the modelling to generate important breakthroughs at the level of basic science with implications for both experimentalists and clinicians.Read moreRead less
Charting connectivity in the healthy and diseased brain. Australia's endemic mental health burden is predicted to escalate as its population ages. This project will: (1) endow medicine with a diagnostic capability enabling earlier and more-accurate diagnosis of brain disorders and mental illnesses; and, (2) pinpoint brain circuit disruptions telltale of particular diseases. This is a world-first and promises a scientific basis for new-generation therapies and treatments. This project will enable ....Charting connectivity in the healthy and diseased brain. Australia's endemic mental health burden is predicted to escalate as its population ages. This project will: (1) endow medicine with a diagnostic capability enabling earlier and more-accurate diagnosis of brain disorders and mental illnesses; and, (2) pinpoint brain circuit disruptions telltale of particular diseases. This is a world-first and promises a scientific basis for new-generation therapies and treatments. This project will enable the APD to disseminate the specialist knowledge acquired as an ARC Fellow at Harvard in 2008 to Australian researchers, thereby advancing Australia's international standing in science.Read moreRead less