Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
New vaccines and diagnostics to control viral disease in farmed crocodiles. Infection of farmed crocodiles with West Nile virus (WNV) causes lesions in the skin that render the hides unsuitable for high quality leather products. This results in >$20 million lost revenue to the Australian crocodile industry annually. We have developed a novel technology to generate safe and effective vaccines and diagnostic tests for WNV in animals. We aim to 1) conduct vaccine trials in farmed crocodiles to dete ....New vaccines and diagnostics to control viral disease in farmed crocodiles. Infection of farmed crocodiles with West Nile virus (WNV) causes lesions in the skin that render the hides unsuitable for high quality leather products. This results in >$20 million lost revenue to the Australian crocodile industry annually. We have developed a novel technology to generate safe and effective vaccines and diagnostic tests for WNV in animals. We aim to 1) conduct vaccine trials in farmed crocodiles to determine the optimum dose formulation and immunisation regime to provide long-lived protection against WNV disease; 2) validate pen-side tests to rapidly diagnose WNV infection in crocodiles on farms; and 3) transfer the technology to a manufacturing facility to ensure a commercial supply of the vaccines and diagnostic tests. Read moreRead less