An Integrated Biotechnological Process for Production of Lactic Acid from Carbohydrate-Waste Streams by Rhizopus sp. Lactic acid is the most widely occurring multifunctional organic acid. It has enormous applications in food and food-related industries, and great potential use for production of biodegradable and biocompatible polylactate polymers. The aim of this research is to develop an innovative biotechnological process, incorporating simultaneous saccharification and fermentation, which int ....An Integrated Biotechnological Process for Production of Lactic Acid from Carbohydrate-Waste Streams by Rhizopus sp. Lactic acid is the most widely occurring multifunctional organic acid. It has enormous applications in food and food-related industries, and great potential use for production of biodegradable and biocompatible polylactate polymers. The aim of this research is to develop an innovative biotechnological process, incorporating simultaneous saccharification and fermentation, which integrates the production of lactic acid with the treatment of high strength food industry ?effluent? streams - carbohydrate waste streams. The proposed SSF process will cultivate an identified fungal Rhizopus sp strain on the waste streams, as production substrates, leading to an environmentally friendly and economically sustainable new technology for the food industry.Read moreRead less
A New Photocatalysis Hybrid System in Wastewater Treatment for Reuse. This project would particularly be useful to unreticulated sewage systems and small sewage treatment plants are prevalent in the coastal areas of NSW and Queensland and the interior parts of Northern Territory with small and isolated communities. Opportunities for demonstrating the successful application of this cost effective method of waste water treatment to appropriate stakeholders through participation in workshops, semin ....A New Photocatalysis Hybrid System in Wastewater Treatment for Reuse. This project would particularly be useful to unreticulated sewage systems and small sewage treatment plants are prevalent in the coastal areas of NSW and Queensland and the interior parts of Northern Territory with small and isolated communities. Opportunities for demonstrating the successful application of this cost effective method of waste water treatment to appropriate stakeholders through participation in workshops, seminars and events will be explored. The study can also be extended to small and medium sized industries in their wastewater treatment. The technology is of direct benefit within the Nation and also has significant export potential. Read moreRead less
Membrane Fouling in Submerged Hollow Fibre Membrane Bioreactor Systems: Theory, Modelling and Fouling Control. The outcomes of this project will provide fundamental insights into the mechanisms of fouling in submerged hollow fibre membrane bioreactors (SHFMBR) and will provide a sound base for optimization of design and operation of SHFMBR systems. Given the crucial role of the SHFMBR in wastewater treatment and water reuse, this project will significantly contribute to the national priority are ....Membrane Fouling in Submerged Hollow Fibre Membrane Bioreactor Systems: Theory, Modelling and Fouling Control. The outcomes of this project will provide fundamental insights into the mechanisms of fouling in submerged hollow fibre membrane bioreactors (SHFMBR) and will provide a sound base for optimization of design and operation of SHFMBR systems. Given the crucial role of the SHFMBR in wastewater treatment and water reuse, this project will significantly contribute to the national priority area of 'an environmentally sustainable Australia (water-a critical resource)'. In addition, the outcomes of this project on quantitative simulation of the gel/cake structure and resulting transport phenomena will promote Australia's reputation for high quality fundamental and applied research in the area of membrane filtration. Read moreRead less
Expert judgment of environmental health risks from exposures to contaminants in urban water systems. Sustainable urban water policy requires informed risk management procedures for health and environmental risks from exposures to many contaminants in urban water systems. This research articulates with the National Water Quality Management Strategy and national guidelines for drinking and recycled water; and it shows barriers to successful community adoption of new sustainable water technologies. ....Expert judgment of environmental health risks from exposures to contaminants in urban water systems. Sustainable urban water policy requires informed risk management procedures for health and environmental risks from exposures to many contaminants in urban water systems. This research articulates with the National Water Quality Management Strategy and national guidelines for drinking and recycled water; and it shows barriers to successful community adoption of new sustainable water technologies. Technical advances in modelling expert opinion will contribute to improved standardised risk assessment frameworks throughout government. The research is fundamental for better decision-making for regulators, suppliers, and managers and it will influence the international development of similar guidelines for sustainable urban water use.Read moreRead less
Electron transfer in proteins, a study of mechanism and function. Our research will probe the mechanisms by which nature's living systems build, maintain, and reproduce. We present an ability to understand these processes at a detailed molecular level using science and technology at the forefront of multidisciplinary research. The research will provide a foundation for new smart materials, technologies and future industries, and also ways forward for future basic scientific research and endeavo ....Electron transfer in proteins, a study of mechanism and function. Our research will probe the mechanisms by which nature's living systems build, maintain, and reproduce. We present an ability to understand these processes at a detailed molecular level using science and technology at the forefront of multidisciplinary research. The research will provide a foundation for new smart materials, technologies and future industries, and also ways forward for future basic scientific research and endeavor. All this is done with the best international researchers and capabilities within a local environment that will help to train the next generation of Australian scientists.Read moreRead less
Mimicking peptide structure - towards an aqueous environment. In this proposal we develop a fundamental understanding of the balance between 'weak' and 'strong' forces to define the properties of peptides and proteins. This will allow the design of new biological probes and materials with tailor-made chemical and physical properties for use in bioengineering, biotechnology, proteomics, and drug design. One such example is the design and preparation of a new chemical agent for the non-surgical tr ....Mimicking peptide structure - towards an aqueous environment. In this proposal we develop a fundamental understanding of the balance between 'weak' and 'strong' forces to define the properties of peptides and proteins. This will allow the design of new biological probes and materials with tailor-made chemical and physical properties for use in bioengineering, biotechnology, proteomics, and drug design. One such example is the design and preparation of a new chemical agent for the non-surgical treatment for cataract, the major cause of blindness world-wide.Read moreRead less
Defining Fundamental Principles for the Design and Operation of Membrane Systems from Time-Varying Performance Analysis. To date, much of the process improvement for industrial application of membrane technology has revolved around polymer science based development of membrane materials and process and module changes resulting from the application of basic (often simplistic) engineering principles. While some future improvements may still come from these areas, the most dramatic advances are li ....Defining Fundamental Principles for the Design and Operation of Membrane Systems from Time-Varying Performance Analysis. To date, much of the process improvement for industrial application of membrane technology has revolved around polymer science based development of membrane materials and process and module changes resulting from the application of basic (often simplistic) engineering principles. While some future improvements may still come from these areas, the most dramatic advances are likely to be derived from the application of advanced engineering principles to this complex system. This project will integrate advanced CFD modelling and control principles for the design and operation of membrane systems in order to develop fundamental understanding that should lead to significant process improvements.Read moreRead less
The use of chiral pharmaceutical compounds to characterise sewage treatment processes and sewage contamination of surface waters. Contamination by poorly treated and untreated sewage can severely degrade the quality of Australian surface waters. However, the behaviour of organic chemicals during conventional sewage treatment processes remains poorly understood. Furthermore, raw sewage pollution is generally not distinguishable from properly discharged treated sewage effluent by current analytica ....The use of chiral pharmaceutical compounds to characterise sewage treatment processes and sewage contamination of surface waters. Contamination by poorly treated and untreated sewage can severely degrade the quality of Australian surface waters. However, the behaviour of organic chemicals during conventional sewage treatment processes remains poorly understood. Furthermore, raw sewage pollution is generally not distinguishable from properly discharged treated sewage effluent by current analytical methods. The proposed research will provide a chemical marker for characterising treatment processes and identifying untreated sewage pollution. This will help to identify sources of such pollution so that they may be corrected. A principal outcome of the research will be the improved ability to protect Australia's valuable surface waters from sewage pollution.Read moreRead less
Healthier Water: Innovative Processes for Arsenic Removal and Sludge Management. Arsenic is a highly toxic metal found in drinking water in parts of Australia and in many parts of the world. The enforcement of stringent arsenic standard for drinking water calls for an effective treatment technology. In this study, an innovative and cost effective treatment system for arsenic removal will be developed for use in small community water supplies. This novel hybrid system consists of buoyant media f ....Healthier Water: Innovative Processes for Arsenic Removal and Sludge Management. Arsenic is a highly toxic metal found in drinking water in parts of Australia and in many parts of the world. The enforcement of stringent arsenic standard for drinking water calls for an effective treatment technology. In this study, an innovative and cost effective treatment system for arsenic removal will be developed for use in small community water supplies. This novel hybrid system consists of buoyant media flocculator and a newly-developed metal oxide coated media adsorption technique to achieve superior arsenic removal. A simple and safe disposal of arsenic sludge will also be established and tested.Read moreRead less
The only constant is change: ecology and evolution of phage-host interactions in a model ecosystem. Microorganisms underpin life on Earth, but our understanding of their diversity and activity is limited by our inability to grow most of them in the laboratory. Recently, new techniques have emerged that allow access to the genetic information of all microorganisms by directly sequencing DNA and RNA from the environment. In this research we will further develop these frontier technologies, promoti ....The only constant is change: ecology and evolution of phage-host interactions in a model ecosystem. Microorganisms underpin life on Earth, but our understanding of their diversity and activity is limited by our inability to grow most of them in the laboratory. Recently, new techniques have emerged that allow access to the genetic information of all microorganisms by directly sequencing DNA and RNA from the environment. In this research we will further develop these frontier technologies, promoting this new area of science in Australia. We will apply these techniques to microbial communities involved in wastewater treatment in order to understand the interactions between microorganisms and the viruses that infect them. Understanding this interaction will have important implications for optimising these treatment processes.Read moreRead less