A National Population-based Genetic Epidemiology, Biospecimen And Bioinformatic Resource
Funder
National Health and Medical Research Council
Funding Amount
$1,900,000.00
Summary
This proposal is to build a new national resource for medical research. The project will integrate human medical research resources (including DNA) in WA with the core WA Data Linkage System, with complementary initiatives in bioinformatics and biostatistics. The resulting unique facility will comprise one of the largest and best-characterised population-based enabling facilities for epidemiological and genetic epidemiological research in the world, and will considerably enhance the national res ....This proposal is to build a new national resource for medical research. The project will integrate human medical research resources (including DNA) in WA with the core WA Data Linkage System, with complementary initiatives in bioinformatics and biostatistics. The resulting unique facility will comprise one of the largest and best-characterised population-based enabling facilities for epidemiological and genetic epidemiological research in the world, and will considerably enhance the national research capacity.Read moreRead less
Multidisciplinary Translational Research To Address Social Disparities In Osteoporosis: Understanding The Social Context Of Biological Mechanisms
Funder
National Health and Medical Research Council
Funding Amount
$419,180.00
Summary
Osteoporosis (OP) prevalence is greater for disadvantaged groups, as are less healthy lifestyles. Whilst reasons for this social gradient of OP are unknown, some biological phenomena are influenced by lifestyle factors. I will provide novel evidence about biological mechanisms underlying the social gradient of OP (epigenetics), and, using that information, engage disadvantaged communities in multidisciplinary discussions to inform effective public health interventions (community engagement).
Novel Retinal Architectural Vascular Signs And Risk Of Cardiovascular Disease: The AusDiab Study
Funder
National Health and Medical Research Council
Funding Amount
$754,254.00
Summary
Cardiovascular disease (CVD) and diabetes are major health problems. Identifying 'people at risk' is critical to design preventative strategies. We have developed new computer software to measure detailed characteristics of retinal vessels. By appling this system to predict CVD or diabetes in the AusDiab Study we aim to find 'the best combination of risk factors' to predict CVD and diabetes. This will open up the possibility of new risk assessment using a simple 'eye scan.'