Modelling trajectories of cognitive control in adolescents and young adults. This project aims to develop an innovative framework that models behaviour, brain function and brain structure to characterise developmental trajectories of cognitive control in typically-developing young people, and to test the model’s ability to predict psychosocial outcomes. Cognitive control processes are supported by complex frontal brain networks that develop well into adulthood. Poor cognitive control is linked t ....Modelling trajectories of cognitive control in adolescents and young adults. This project aims to develop an innovative framework that models behaviour, brain function and brain structure to characterise developmental trajectories of cognitive control in typically-developing young people, and to test the model’s ability to predict psychosocial outcomes. Cognitive control processes are supported by complex frontal brain networks that develop well into adulthood. Poor cognitive control is linked to negative psychosocial outcomes (e.g. substance use, high-risk behaviours). This work is expected to inform evidence-based programmes that identify young people at risk and develop targeted training strategies to improve psychosocial outcomes.Read moreRead less
Make up your mind! - Dissociating the roles of orbitofrontal cortex and striatum in human decision making. How we make everyday decisions is a crucial behaviour of humans but the underlying processes in the brain are still poorly understood. This project will investigate what the roles of specific brain regions are in human decision making, which enable us to gain a better understanding of how these brain structures contribute to our decisions.
Cognitive flexibility from adolescence to senescence: variability associated with cognitive strategy and brain connectivity. Healthy living in our complex and unpredictable world depends on the ability to flexibly adjust to novelty and change. This project will study how cognitive flexibility changes from adolescence to senescence, identify the brain networks that mediate this change and explore the implications for successful adaptation in everyday life.
The Neural Bases of Decision-Making. The smooth integration of cognitive and emotional processes is necessary for everyday decisions. Dysfunction in this integrative capacity accompanies dementia, neurodegenerative conditions and major psychiatric disorders. This project seeks to understand the neural bases of this integration in normal decision-making using cutting edge behavioural, cellular, molecular and genetic tools to map the neural system, circuit and cellular processes controlling the se ....The Neural Bases of Decision-Making. The smooth integration of cognitive and emotional processes is necessary for everyday decisions. Dysfunction in this integrative capacity accompanies dementia, neurodegenerative conditions and major psychiatric disorders. This project seeks to understand the neural bases of this integration in normal decision-making using cutting edge behavioural, cellular, molecular and genetic tools to map the neural system, circuit and cellular processes controlling the selection, evaluation and choice of goal-directed actions. Such actions can, with continued practice, transition into relatively inflexible habits. Thus, this project aims to investigate the neural processes that mediate this transition and how actions and habits interact in normal decision-making.Read moreRead less
Attention please! Selective attention and human associative learning. Selective attention allows us to pick useful pieces of information out of the mass of stimulation that we're faced with every moment. This project investigates how what we've previously learnt about the significance of events influences whether we'll pick them out as useful in future, and how this might be impaired by old age or mental disorder.