Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100001
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
An advanced thermogravimetric analysis system for world-leading research in clean energy, catalysis, material science and nanotechnology. Many chemical reactions occurring in solid materials during heating significantly affect the materials' stability, and subsequently affects the processes of production of clean energy, material synthesis, catalyst preparation, and nanotechnology. No equipment currently exists in Australia that will mitigate the wide range of conditions in such reactions in ma ....An advanced thermogravimetric analysis system for world-leading research in clean energy, catalysis, material science and nanotechnology. Many chemical reactions occurring in solid materials during heating significantly affect the materials' stability, and subsequently affects the processes of production of clean energy, material synthesis, catalyst preparation, and nanotechnology. No equipment currently exists in Australia that will mitigate the wide range of conditions in such reactions in materials processing. This situation impedes research progress in Australia, disadvantages Australian research students, and ultimately makes our research less competitive internationally. The establishment of the proposed apparatus will increase the competitiveness of Australian science and engineering, and contribute to the development of new Australian technologies that are important to the Australian economy and to environmental sustainability.Read moreRead less
Pushing AR Toward Better Outcomes In Breast And Prostate Cancers
Funder
National Health and Medical Research Council
Funding Amount
$998,754.00
Summary
Breast and prostate cancers kill >6000 Australians each year. These cancers are strikingly similar, both driven by hormone receptors that have ‘gone bad’. Current therapies aim to eradicate the receptors. While often effective, therapeutic resistance is common and results in fatal disease. We aim to develop new, less toxic treatments that switch receptor behaviour from good to bad, without destroying them. This should improve quality of life, while preventing drug resistance and loss of lives ....Breast and prostate cancers kill >6000 Australians each year. These cancers are strikingly similar, both driven by hormone receptors that have ‘gone bad’. Current therapies aim to eradicate the receptors. While often effective, therapeutic resistance is common and results in fatal disease. We aim to develop new, less toxic treatments that switch receptor behaviour from good to bad, without destroying them. This should improve quality of life, while preventing drug resistance and loss of lives.Read moreRead less
Investigation of the coupled dependence of concentrated solar radiation and combustion in a novel solar hybrid technology. The project will develop the models necessary for the optimisation of a novel solar-combustion hybrid technology and a novel heat exchanger component. It will deliver a solar thermal technology that lowers the cost of solar energy with immediate potential in off-grid sites, such as in remote mines, in Australia and throughout the world.
Commercial scale production of biocrude by hydrothermal liquefaction. The project aims to develop new understanding and tools to support commercial-scale production of biocrude from microalgae or biosolids and enable a breakthrough in cost-effective production of sustainable fuels. A novel hydrothermal liquefaction reactor has been developed that has strong potential to overcome the limitations of Muradel's existing demonstration reactor which, while world-leading, is uneconomical at commercial ....Commercial scale production of biocrude by hydrothermal liquefaction. The project aims to develop new understanding and tools to support commercial-scale production of biocrude from microalgae or biosolids and enable a breakthrough in cost-effective production of sustainable fuels. A novel hydrothermal liquefaction reactor has been developed that has strong potential to overcome the limitations of Muradel's existing demonstration reactor which, while world-leading, is uneconomical at commercial scale. The project aims to develop design tools to optimise the new reactor, comprising a chemical model of the complex, multi-component hydrothermal liquefaction reactions, a computational model of the mixing and heat transfer within it and a network model of the energy and exergy flows.Read moreRead less
A Randomised Controlled Trial (RCT) Of Azithromycin Versus Doxycycline For The Treatment Of Rectal Chlamydia Infection In Men Who Have Sex With Men.
Funder
National Health and Medical Research Council
Funding Amount
$797,906.00
Summary
Rectal chlamydia is very common among gay men; it can exist for long periods without symptoms leading to ongoing transmission. Azithromycin (1 gram single dose) or 7 days doxycycline (100mg twice daily) are the two recommended treatments globally. But, there is concern about rectal chlamydia treatment with reports of up to 22% failure following azithromycin. We will conduct a randomised trial to compare these treatments for rectal chlamydia and determine which drug works better.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100220
Funder
Australian Research Council
Funding Amount
$760,000.00
Summary
Adaptive Electrical Capacitance Volume Tomography for Multiphase Flows. This project aims to establish a cutting edge adaptive electrical capacitance volume tomography facility for real-time metering / imaging of multi-phase flows. Optimisation of these flows which are encountered in many industries, is paramount in today's carbon-constrained global economy. This project expects to generate the new knowledge necessary for such optimisations. Expected outcomes include enhanced national capability ....Adaptive Electrical Capacitance Volume Tomography for Multiphase Flows. This project aims to establish a cutting edge adaptive electrical capacitance volume tomography facility for real-time metering / imaging of multi-phase flows. Optimisation of these flows which are encountered in many industries, is paramount in today's carbon-constrained global economy. This project expects to generate the new knowledge necessary for such optimisations. Expected outcomes include enhanced national capability for characterisation of multi-phase flows in real-time under both ambient and high temperatures. This should benefit and greatly facilitate the commercial rollout of novel technologies in industrial sectors as diverse as mineral processing, clean energy, fuels/chemicals, oil/gas, food and environmental remediation. Read moreRead less
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revol ....ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revolutionizing diagnosis and therapy in many diseases. The CoE will be the focus of bio-nano research activity in Australia, uniting universities, research agencies, institutes and companies. The expected outcomes are better diagnostic and therapeutic tools designed via an enhanced understanding of the bio-nano-interface.Read moreRead less
An In Depth Analysis Of Clinical And Virological Outcomes Of 2 Strategies For The Antiretroviral Salvage Of First-line Regimen Virological Failure For HIV-1 Infection Tested In An Australian-led Randomised, International, Multi-centre Clinical Trial
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
The recently completed Australian-led SECOND-LINE trial is the first high quality study to provide reliable evidence for policy recommendations for the composition of anti-HIV drug cocktails after standard initial treatment has failed. This award will support the researcher in further refining our understanding of how to manage second-line therapy including proposals to test the use of low-cost technologies for application in resource-limited settings where the majority of people with HIV live.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100225
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Multi-dimensional, high speed laser imaging facility for fluids and combustion. New high-speed laser diagnostics facilities will be established to enable Australian researchers to perform unique, real time measurements in combustion systems. Such novel capabilities will advance the science of combustion and facilitate the development of design tools for the optimisation of clean and efficient energy conversion devices.