Use of quinone adducted peptides in the regulation of fertility. This project describes a novel strategy for the non-surgical induction of sterility in male and female mammals with applications in the fields of biotechnology, veterinary medicine and the humane control of pest animal species. The approach is dependent upon the known sensitivity of the germ line to oxidative stress. The strategy rests upon the demonstration that quinone-adducted peptides will selectively bind to non-renewable cel ....Use of quinone adducted peptides in the regulation of fertility. This project describes a novel strategy for the non-surgical induction of sterility in male and female mammals with applications in the fields of biotechnology, veterinary medicine and the humane control of pest animal species. The approach is dependent upon the known sensitivity of the germ line to oxidative stress. The strategy rests upon the demonstration that quinone-adducted peptides will selectively bind to non-renewable cell types in the ovary and testis and redox cycle at the cell surface generating a highly localised state of oxidative stress. This stress will then recapitulate the impact of radiation on reproductive tissues by selectively compromising the viability of the germ line, inducing a state of sterility.Read moreRead less
International Trade Policy and the Dynamics of Open Economies. The project is concerned with the relationship between an open economy's international trading conditions and the allocation of resources within the economy, particularly over time (dynamic effects). The trading conditions reflect international markets and governments' trade policies. The dynamic effects upon the economy include the rate of growth, saving and inter-generation welfare. The models developed to study these relationship ....International Trade Policy and the Dynamics of Open Economies. The project is concerned with the relationship between an open economy's international trading conditions and the allocation of resources within the economy, particularly over time (dynamic effects). The trading conditions reflect international markets and governments' trade policies. The dynamic effects upon the economy include the rate of growth, saving and inter-generation welfare. The models developed to study these relationships will link international markets with domestic and future markets in a unified and consistent manner. The outcomes include a better theoretical understanding of these relationships and empirical inter-temporal models for the Australian economy that permit measurement of these dynamic effects.Read moreRead less
Manipulative mothers and family feuds: evolution of maternal effects under mother-offspring conflict. Can mothers shape the lives of their offspring and their grand-offspring? Can siblings shape the lives of their brothers and sisters? This project will address how mother and offspring strategies affect current and future generations. This is crucial for understanding how mothers will direct and accelerate evolutionary change in our changing world.
Understanding leaf water isotope composition. This project aims to quantify variation in leaf water isotopes and develop mechanistic models for paleoclimatologists and plant scientists to constrain global carbon cycles. Leaf water stable isotopes influence the isotope compositions of atmospheric oxygen, carbon dioxide and water vapour, and impart an evaporative signal on the isotope composition of plant organic material. These isotope signals have been used to constrain global carbon and water c ....Understanding leaf water isotope composition. This project aims to quantify variation in leaf water isotopes and develop mechanistic models for paleoclimatologists and plant scientists to constrain global carbon cycles. Leaf water stable isotopes influence the isotope compositions of atmospheric oxygen, carbon dioxide and water vapour, and impart an evaporative signal on the isotope composition of plant organic material. These isotope signals have been used to constrain global carbon and water cycles and reconstruct past climates. This project aims to quantify variation in leaf water isotopes and develop mechanistic models for use by paleoclimatologists, plant scientists and to constrain global carbon cycles and develop accurate models of leaf water isotopes to reduce uncertainty in climate models.Read moreRead less
Evolution of intelligence in small brains: how to navigate the messy natural outdoors smartly. This project unravels how small-brained desert ants navigate expertly using simple and coarse-grade visual cues, focusing on 1) how they use skylines, where the tops of terrestrial objects meet the sky, and 2) how they search efficiently for goals. The outcomes will be invaluable for designing robots that can navigate in the messy natural outdoors.
Lively reproduction: do common molecules underlie all vertebrate live birth? Most animals lay eggs, but some (most mammals, including humans and some reptiles) give birth to live young. This project will reveal the molecules underlying the evolution of live birth and fundamental processes of early pregnancy, which potentially will lead to future developments in reproductive science.
Are proposed land-based sinks for greenhouse gases resilient to climate change and natural variability? One strategy to reduce the scale of future climate change is to enhance the storage of carbon in vegetation and soils. Evidence suggests carbon stored in vegetation and soils is itself vulnerable to climate change, placing this stored carbon at risk; this project will assess this risk to advise on the reliability of using terrestrial systems as carbon sinks.
Are subterranean estuaries a source or sink of greenhouse gases? The aim of this project is to investigate the role of subterranean estuaries and submarine groundwater discharge on the marine cycle of the greenhouse gases carbon dioxide, methane, and nitrous oxide. The expected outcome of this project is a better understanding of the role of coastal environments as a net source or sink of greenhouse gases.
Incorporating new knowledge of phytoplankton diversity and nutrient utilisation into an ocean-climate model to improve forecasts of ocean function. Phytoplankton drives ocean biogeochemical cycles and regulate Earth’s climate yet are poorly represented in ocean-climate models. This project will use advanced cell sorting and analysis techniques and innovative selection experiments to gain a deeper understanding of phytoplankton diversity and nutrient utilisation under projected climate change. Th ....Incorporating new knowledge of phytoplankton diversity and nutrient utilisation into an ocean-climate model to improve forecasts of ocean function. Phytoplankton drives ocean biogeochemical cycles and regulate Earth’s climate yet are poorly represented in ocean-climate models. This project will use advanced cell sorting and analysis techniques and innovative selection experiments to gain a deeper understanding of phytoplankton diversity and nutrient utilisation under projected climate change. This new knowledge will be used to improve the biological structure of an existing coupled ocean-climate model and reduce key uncertainties in forecasts of ocean function. This research will provide managers and industry with more accurate insight into the effects of ongoing climate change on the delivery of ecosystem services in eastern Australian waters.Read moreRead less
Remote forcing of Pacific Ocean variability and impacts on global climate. Variability in the Pacific Ocean has a profound impact on global climate. Recent unprecedented decadal variability in the Pacific has been linked to global temperature trends and extremes, yet little is known about what drives this variability or its impact on regional climate. This project will combine observations, advanced coupled climate models and ocean-atmosphere dynamical theory to quantify remote drivers of Pacifi ....Remote forcing of Pacific Ocean variability and impacts on global climate. Variability in the Pacific Ocean has a profound impact on global climate. Recent unprecedented decadal variability in the Pacific has been linked to global temperature trends and extremes, yet little is known about what drives this variability or its impact on regional climate. This project will combine observations, advanced coupled climate models and ocean-atmosphere dynamical theory to quantify remote drivers of Pacific Ocean variability on interannual-decadal time-scales. This project aims to enhance our understanding of the modes of variability operating in this region and their impact on global and Australian climate. This will have significant benefits for the many sectors of society reliant on interseasonal-decadal climate prediction.Read moreRead less