A Novel Optical Stimulation Method For Obstructive Sleep Apnoea Treatment
Funder
National Health and Medical Research Council
Funding Amount
$510,913.00
Summary
This project aims to develop and characterize a novel optogenetic pharyngeal stimulation system to dilate the upper airway using a light stimulus. This will provide proof-of-concept for a new minimally invasive treatment option for obstructive sleep apnoea.
Chronotherapy For Hypertension In Obstructive Sleep Apnoea
Funder
National Health and Medical Research Council
Funding Amount
$57,921.00
Summary
This randomised, double blind placebo controlled cross-over trial aims to determine whether evening ingestion of blood pressure medication results in superior blood pressure control as compared to morning ingestion in patients with high blood pressure and obstructive sleep apnoea.
The Role Of Arousal And Respiratory Control Factors In The Pathogenesis Of Obstructive Sleep Apnoea
Funder
National Health and Medical Research Council
Funding Amount
$567,924.00
Summary
Sleep apnoea (OSA) is a very common breathing disorder in sleep characterized by repetitive closure of the collapsible portion of the throat with serious effects on sleep quality and health. Basic causes of OSA are still largely unknown. We will investigate waking responses to breathing load and related respiratory control factors that we believe may be fundamental causes of OSA, and potentially explain many features of OSA including worsening in light sleep and with increasing age.
Cerebral Circulation In Sleep: Impact Of Endothelial Dysfunction
Funder
National Health and Medical Research Council
Funding Amount
$313,026.00
Summary
Prolonged, repetitive episodes of obstructed breathing during sleep (known as obstructive sleep apnoea syndrome or OSA) is a common medical problem that afflicts both children and adults. As many as 200,000 Australian adults and 300,000 children are affected. OSA has major medical consequences, amongst the most serious being cognitive deficits in children and vascular disease and stroke in adults. This experimental study investigates blood flow to the brain in normal sleep, and in sleep disrupte ....Prolonged, repetitive episodes of obstructed breathing during sleep (known as obstructive sleep apnoea syndrome or OSA) is a common medical problem that afflicts both children and adults. As many as 200,000 Australian adults and 300,000 children are affected. OSA has major medical consequences, amongst the most serious being cognitive deficits in children and vascular disease and stroke in adults. This experimental study investigates blood flow to the brain in normal sleep, and in sleep disrupted OSA, as many of the problems associated with OSA may have their origin in disturbance of blood flow to the brain.Read moreRead less