Improving Treatment Strategies For Chronic Alphaviral Arthritic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$643,624.00
Summary
Chikungunya virus and Ross River virus cause epidemics of acute and chronic arthritic disease in humans, which is often poorly managed with current treatments. This grant seeks to understand the mechanisms that give rise to disease in order to identify improved treatment strategies. Both the persistence of viral replication in joint tissues and unnecessary inflammatory responses appear to be important factors driving chronic disease.
New Insights Into Viral Inflammatory Disease Mechanisms And Approaches To Therapy
Funder
National Health and Medical Research Council
Funding Amount
$631,010.00
Summary
This fellowship aims to establish how viruses cause disease, including how they evade the immune response to persist and cause disease for prolonged periods. My vision is that knowing how the virus and the immune system interact to determine disease severity will assist in devising new treatments and prevention programs to lessen the impact of viral diseases in Australia and worldwide.
Optimising lasers for ablation of structurally complex solid non-metals. This project aims to take the latest developments in fibre laser technology to create a new ablation system for precision cutting and reshaping of structurally complex non-metal materials. Fibre lasers provide high quality beams, high average power, and precise pulse timing. Guided by the composition of the material and its response to incident mid-infrared light, the project will create a tailored laser beam to provide ac ....Optimising lasers for ablation of structurally complex solid non-metals. This project aims to take the latest developments in fibre laser technology to create a new ablation system for precision cutting and reshaping of structurally complex non-metal materials. Fibre lasers provide high quality beams, high average power, and precise pulse timing. Guided by the composition of the material and its response to incident mid-infrared light, the project will create a tailored laser beam to provide accurate and high-rate ablation. The expected outcomes include minimal damage to the surrounding area and a level of precision not possible with any mechanical alternative. The project will provide long term benefits to the aerospace and healthcare industries and, be a boost to Australia’s manufacturing sector.Read moreRead less
Excessive sitting and population health: strengthening the science and the relevance to policy and practice. The majority of Australian adults spend most of their waking hours sitting; this increases the likelihood of developing diseases of inactivity, including diabetes, heart disease and some cancers. New research will investigate what factors encourage excessive sitting and what the health benefits are for people who deliberately do less sitting.
Indigenous young people's resilience and wellbeing. This project aims to identify factors related to, and those which predict, the development of resilience and wellbeing in Indigenous youth. Resilience protects the social and emotional wellbeing of youth exposed to high levels of adversity, and reduces the likelihood of substance misuse, violence, and risky behaviour. This project will examine the development of resilience and wellbeing in Indigenous youth; compare Indigenous youth’s self-asses ....Indigenous young people's resilience and wellbeing. This project aims to identify factors related to, and those which predict, the development of resilience and wellbeing in Indigenous youth. Resilience protects the social and emotional wellbeing of youth exposed to high levels of adversity, and reduces the likelihood of substance misuse, violence, and risky behaviour. This project will examine the development of resilience and wellbeing in Indigenous youth; compare Indigenous youth’s self-assessment of their resilience and wellbeing between low and high risk cohorts; and study how community services develop youth wellbeing and resilience. The expected benefit of this research is a better understanding of connections among age, cultural identity, resilience, wellbeing and risky behaviours in Indigenous youth.Read moreRead less
Strengthening Indigenous adolescent mental health and wellbeing. Using Continous Quality Improvement processes, the research will collaboratively conceptualise, design, implement and evaluate the effectiveness of new approaches to mental health service delivery for adolescents aged 10-24 in three regionally diverse Indigenous Primary Healthcare Services. Expected research outcomes are a rigorous assessment of the impact and economic benefits of making quality improvements to mental health servic ....Strengthening Indigenous adolescent mental health and wellbeing. Using Continous Quality Improvement processes, the research will collaboratively conceptualise, design, implement and evaluate the effectiveness of new approaches to mental health service delivery for adolescents aged 10-24 in three regionally diverse Indigenous Primary Healthcare Services. Expected research outcomes are a rigorous assessment of the impact and economic benefits of making quality improvements to mental health services for Indigenous adolescents, Key benefits are 1) A locally-responsive adolescent mental health screening instrument; 2) Comprehensive evidence-informed service model in adolescent mental healthcare; 3) Best practice protocol for developing and managing adolescent mental health as a service delivery stream. Read moreRead less