Common synaptic inputs to human upper airway muscles. Changes in the activity of upper airway muscles at sleep onset contribute to the development of Obstructive Sleep Apnoea. The aim of this project is to investigate how the brain controls upper airway muscles during wakefulness and sleep and to identify the pathological processes that lead to the development of Obstructive Sleep Apnoea.
From The Synchrotron To The Clinic: Translation Of A Novel Functional Lung Imaging Technology
Funder
National Health and Medical Research Council
Funding Amount
$891,834.00
Summary
Our team has recently developed a synchrotron technology with a startling capacity for dynamic functional imaging that can act as a sensitive regional indicator of lung disease. We will demonstrate that this technology can be translated from the synchrotron to the lab and eventually the clinic. We will provide proof of this concept by the application of this technology to emphysema, asthma, lung cancer, cystic fibrosis lung disease and neonatal resuscitation.