Discovery Early Career Researcher Award - Grant ID: DE140100100
Funder
Australian Research Council
Funding Amount
$375,289.00
Summary
Mediating mental health: an integrated approach to investigating media and social actors. This project advances knowledge about how the media shapes public and professional understandings and communication practices about mental health issues. Media processes are mostly studied in isolation but this project integrates analyses of media with interviews with lay people, advocacy organisations, expert mental health sources and journalists to identify how mental health knowledge is identified, inter ....Mediating mental health: an integrated approach to investigating media and social actors. This project advances knowledge about how the media shapes public and professional understandings and communication practices about mental health issues. Media processes are mostly studied in isolation but this project integrates analyses of media with interviews with lay people, advocacy organisations, expert mental health sources and journalists to identify how mental health knowledge is identified, interpreted and communicated. It will provide an evidence base for policy directed at promoting mental health and challenging stigma, within the context of dynamic change to digital media environments and media use.Read moreRead less
Alpha-2-Macroglobulin And The Transport And Uptake Of The Hormone, Hepcidin
Funder
National Health and Medical Research Council
Funding Amount
$533,541.00
Summary
Hepcidin is a peptide hormone that is a major regulator of iron metabolism. It has been suggested that hepcidin is free in the blood. However, we recently identified that hepcidin binds with alpha-2-macroglobulin (a2-M) in the plasma and this increases the efficacy of this peptide. The demonstration that a2-M plays a role in hepcidin biology will lead to a better understanding of hepcidin physiology, the development of methods for its measurement and improved treatment of iron related diseases.
Discovery Early Career Researcher Award - Grant ID: DE170100829
Funder
Australian Research Council
Funding Amount
$353,000.00
Summary
The effects of parental education on child health outcomes. This project aims to understand how public education policies can improve health. Common economic analysis of returns to education fails to capture the critical secondary beneficial effects of parental education on future generations’ health. These positive effects are systematically undercounted in the cost-benefit analysis of Australia’s investment in education. This project will use Australian datasets and natural experiments to iden ....The effects of parental education on child health outcomes. This project aims to understand how public education policies can improve health. Common economic analysis of returns to education fails to capture the critical secondary beneficial effects of parental education on future generations’ health. These positive effects are systematically undercounted in the cost-benefit analysis of Australia’s investment in education. This project will use Australian datasets and natural experiments to identify how parental education affects the health outcomes of the second generation. This project expects to provide policy recommendations to maximise health, wellbeing and economic outcomes for Australia.Read moreRead less
Improving mental health nurses’ retention and quality of nursing practice. This project aims to improve mental health nurses’ resilience, retention and quality of practice through implementation of a resilience-building program. There is a critical national shortage of nurses in mental health, and attrition of the mental health nursing workforce is due in large part to workplace stressors. As a world-first in the field, the study will compare outcomes for mental health nurses who participate in ....Improving mental health nurses’ retention and quality of nursing practice. This project aims to improve mental health nurses’ resilience, retention and quality of practice through implementation of a resilience-building program. There is a critical national shortage of nurses in mental health, and attrition of the mental health nursing workforce is due in large part to workplace stressors. As a world-first in the field, the study will compare outcomes for mental health nurses who participate in the resilience program with a group of nurses who do not. Extending on a successful pilot, we expect the outcomes to be improved nurse resilience, turnover intention, and quality of nursing practice, and reduced negative psychological impacts of workplace stress. Read moreRead less
Communicating Risk: Journalistic news values, and medical, health professional and lay discourses on suicide and mental illness. Traditional journalistic practices in reporting suicide and mental health/illness issues are under strong challenge from a variety of groups, including medical/health professionals, and people diagnosed with mental illness. The project investigates the changing dynamics and hotly contested interplay between media, journalistic, medical, health professional and lay disc ....Communicating Risk: Journalistic news values, and medical, health professional and lay discourses on suicide and mental illness. Traditional journalistic practices in reporting suicide and mental health/illness issues are under strong challenge from a variety of groups, including medical/health professionals, and people diagnosed with mental illness. The project investigates the changing dynamics and hotly contested interplay between media, journalistic, medical, health professional and lay discourses about these issues, using in-depth interviews, focus groups and media analyses. How do media label events and people, and how do various audiences interpret and manage this information? Key outcomes include theoretically informed understandings of the positions of key stakeholders and policy advice for government and health professionals in planning communication strategies.Read moreRead less
Affective sensing technology for the detection and monitoring of depression and melancholia. This project will develop reliable and affective sensing technology and evaluate it as an objective measure of depressive disorders; a leading cause of disability worldwide. Outcomes will significantly support and aid clinicians in their diagnosis and treatment, thus providing a major breakthrough with significant research, healthcare and commercial possibilities.
Discovery Early Career Researcher Award - Grant ID: DE200100435
Funder
Australian Research Council
Funding Amount
$365,039.00
Summary
Modern statistical methods for complex multivariate longitudinal data. The project aims to develop novel approaches for the statistical analysis of large, complex multivariate longitudinal data, and apply them to two datasets to address scientific questions related to the drivers and consequences of poor physical and mental health in Australia, and the spatio-temporal evolution of species assemblages in the Southern Ocean. The project expects to develop new knowledge in the areas of statistical ....Modern statistical methods for complex multivariate longitudinal data. The project aims to develop novel approaches for the statistical analysis of large, complex multivariate longitudinal data, and apply them to two datasets to address scientific questions related to the drivers and consequences of poor physical and mental health in Australia, and the spatio-temporal evolution of species assemblages in the Southern Ocean. The project expects to develop new knowledge in the areas of statistical model building, model selection, and inference for multivariate longitudinal data. This will lead to a suite of modern methods and insights for computationally efficient, mathematically rigorous statistical data analysis that, when applied, should provide significant benefits to public health and ecology.Read moreRead less
Perception, interpretation, and the explanation of delusional beliefs. The occurrence of bizarrely false beliefs, called delusions, presents challenges, not only for clinical psychiatric practice, but also for psychology, neuroscience, and philosophy. The aim of this project is to make a distinctively philosophical contribution to our understanding of delusional beliefs by addressing three philosophical questions raised by the study of delusions, questions about perception, interpretation, and e ....Perception, interpretation, and the explanation of delusional beliefs. The occurrence of bizarrely false beliefs, called delusions, presents challenges, not only for clinical psychiatric practice, but also for psychology, neuroscience, and philosophy. The aim of this project is to make a distinctively philosophical contribution to our understanding of delusional beliefs by addressing three philosophical questions raised by the study of delusions, questions about perception, interpretation, and explanation. Answers to these questions will constitute substantial contributions to three central areas of philosophy, but their significance also extends beyond philosophy. They will impact on the scientific investigation of delusions and will contribute indirectly to the treatment and rehabilitation of sufferers.
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Behaviour and emotional problems in young children with developmental delay. This research will provide health professionals, researchers and service providers with a reliable and valid measure to assess behaviour in young children with developmental delay. This will be the first instrument of its kind worldwide. The study will provide the largest and most comprehensive survey of behaviour and emotional problems in young children with developmental delay internationally to date. It will provide ....Behaviour and emotional problems in young children with developmental delay. This research will provide health professionals, researchers and service providers with a reliable and valid measure to assess behaviour in young children with developmental delay. This will be the first instrument of its kind worldwide. The study will provide the largest and most comprehensive survey of behaviour and emotional problems in young children with developmental delay internationally to date. It will provide information on the types of treatment that are needed for these children and what support is needed for their families. The outcomes of this study have the potential to promote the best possible start in life and long term mental health of this group of at risk and disadvantaged young Australians.Read moreRead less
Discovery Of A Novel Immune Evasion Strategy Employed By Mosquito Borne Viruses To Suppress Antiviral Immune Responses
Funder
National Health and Medical Research Council
Funding Amount
$418,642.00
Summary
The transition from mosquitoes, ticks, or other invertebrate vectors to the human hosts represents a crucial step in the successful establishment of arthropod borne viruses (arboviruses). The incidence of arbovirus infections such as dengue virus, West Nile virus, Ross River virus is increasing at an alarming rate in various parts of the world. In addition, the emergence of new viruses resulting in significant mortality in the population is of utmost concern. Vaccines for many of these viruses r ....The transition from mosquitoes, ticks, or other invertebrate vectors to the human hosts represents a crucial step in the successful establishment of arthropod borne viruses (arboviruses). The incidence of arbovirus infections such as dengue virus, West Nile virus, Ross River virus is increasing at an alarming rate in various parts of the world. In addition, the emergence of new viruses resulting in significant mortality in the population is of utmost concern. Vaccines for many of these viruses remain elusive. One factor that contributes to this is the ability of viruses to develop ingenious strategies to avoid or suppress the host defence systems, which enable its successful establishment in the host. Understanding how viruses evade-suppress host defence machinery will certainly enhance and improve our approaches to fight them. For the first time internationally we have discovered a new and novel pathway employed by arboviruses to suppress antiviral immune responses in the host. We have discovered that naturally occurring carbohydrates on viruses derived from mosquito cells, would influence these virus s ability to evade-suppress host antiviral proteins such as interferons. This may be a general effect of arboviruses or may even extend to other viruses , which include a number of deadly pathogens (HIV, Influenza). This research has the potential to significantly expand our understanding of how these viruses establish infection and cause disease. Also this discovery has broader implications for understanding inflammatory processes and their regulation.Read moreRead less