Translating Genetic Determinants Of Glaucoma Into Better Diagnosis And Treatment
Funder
National Health and Medical Research Council
Funding Amount
$9,466,000.00
Summary
Glaucoma is the leading cause of irreversible blindness worldwide. By 2020, it will affect 80 million people, and in Australia over the next decade, the overall cost of glaucoma will reach $4.3 billion per annum. This Program will use genetic advances to personalise treatment. Blindness will be prevented in individuals at highest risk, new ways to treat patients will be developed, and better outcomes for patients will result from less treatment and monitoring of low risk cases.
Eliminating Hepatitis C Transmission By Enhancing Hepatitis C Care And Treatment In Primary Health Care Settings.
Funder
National Health and Medical Research Council
Funding Amount
$1,221,831.00
Summary
In developed countries, people who inject drugs (PWID) are the group at greatest risk of hepatitis C (HCV) infection but few PWID receive HCV treatment. With the advent of highly effective non-interferon based treatments HCV elimination, although ambitious, is now being seriously considered globally. This partnership grant will explore the feasibility of eliminating HCV transmission by enhancing HCV care and treatment for PWID in primary health care settings.
A Randomised Controlled Trial Of Enhanced Parenting Capacity To Improve Developmental Outcomes In Preterm Infants
Funder
National Health and Medical Research Council
Funding Amount
$1,045,141.00
Summary
In Australia there are 2, 600 very preterm survivors each year. 50% will have education/behavioural difficulties and 10% major disability. We aim to optimise the development of infants born very preterm through a tailored Positive Parenting Program. We predict reductions in child behavioural and emotional problems at 2 years corrected age.
Defend or retreat? Adapting to the impacts of sea level rise as a result of rapid climate change.
. Rapid sea level rise has been identified as a major threat to coastal Australia, where most of the Australian population lives. Our understanding and ability to respond to this threat is extremely limited at this point. This project will directly benefit Australian communities and businesses, specifically those in southeast Queensland by bringing together a team of distinguished, multidiscipli ....Defend or retreat? Adapting to the impacts of sea level rise as a result of rapid climate change.
. Rapid sea level rise has been identified as a major threat to coastal Australia, where most of the Australian population lives. Our understanding and ability to respond to this threat is extremely limited at this point. This project will directly benefit Australian communities and businesses, specifically those in southeast Queensland by bringing together a team of distinguished, multidisciplinary researchers and Super Science Fellows to explore the threats and challenges posed by rapidly rising sea levels. By building capacity and answering many urgent and difficult questions related to the legal, environmental and planning ramifications of sea level rise, this project will prepare communities and policymakers for the difficult times ahead.Read moreRead less
Role of nitrogen-rich compounds for increasing carbon sequestration in soil. This project aims to unravel how increasing concentrations of nitrogen-rich compounds in soils can potentially increase our ability to sequester soil organic carbon. This is significant because long-term agricultural production greatly reduces soil organic carbon stocks and releases carbon dioxide as a greenhouse gas. Expected outcomes of this project include providing information that is urgently needed to develop pred ....Role of nitrogen-rich compounds for increasing carbon sequestration in soil. This project aims to unravel how increasing concentrations of nitrogen-rich compounds in soils can potentially increase our ability to sequester soil organic carbon. This is significant because long-term agricultural production greatly reduces soil organic carbon stocks and releases carbon dioxide as a greenhouse gas. Expected outcomes of this project include providing information that is urgently needed to develop predictive carbon models for effective policy-making and improved management. This project should provide substantial benefits, including fulfilling the carbon sequestration potential of Australia’s soils, thereby delivering positive economic outcomes through increased farm-gate output and mitigation of climate change.Read moreRead less
Transition to a clean energy future: the role of climate change litigation in shaping our regulatory path. As the world seeks a clean energy future, courts in Australia and other key fossil fuel-producing nations, like the United States, are increasingly hearing cases seeking to block the use of coal due to its climate change effects. This project critically assesses the role such climate litigation plays in generating regulatory momentum to address climate change.
Algal direct-air CO2 capture through interfacial enzyme immobilisation . Capturing CO2 directly from the atmosphere is challenging due to inherently slow mass transfer kinetics. This project aims to overcome this using an enzyme that can rapidly solubilise CO2 from air into water, to produce algae. By engineering the enzyme immobilisation at the air-water interface, this project will activate and protect the enzymes, increasing their lifespan and reducing costs. By understanding mass transfer an ....Algal direct-air CO2 capture through interfacial enzyme immobilisation . Capturing CO2 directly from the atmosphere is challenging due to inherently slow mass transfer kinetics. This project aims to overcome this using an enzyme that can rapidly solubilise CO2 from air into water, to produce algae. By engineering the enzyme immobilisation at the air-water interface, this project will activate and protect the enzymes, increasing their lifespan and reducing costs. By understanding mass transfer and enzyme activity in the interfacial immobilisation media, floating enzyme rafts can be developed for deployment over expansive areas, facilitating large-scale conversion of atmospheric CO2 into algae-derived fuels, feeds and chemicals.Read moreRead less
Advancing investor action on energy transition. This project aims to advance action by investors (debt and equity) to increase finance for low-carbon energy sources that reduce fundamental climate risks. The project applies interdisciplinary approaches to generate new knowledge about the business case for investor leadership on energy transition and supportive climate law and financial regulatory frameworks. Collaborative legal and business analysis by leading Australian and US scholars, coupled ....Advancing investor action on energy transition. This project aims to advance action by investors (debt and equity) to increase finance for low-carbon energy sources that reduce fundamental climate risks. The project applies interdisciplinary approaches to generate new knowledge about the business case for investor leadership on energy transition and supportive climate law and financial regulatory frameworks. Collaborative legal and business analysis by leading Australian and US scholars, coupled with interviews and focus groups with investors, will examine contemporary engagement practices and investors' management of climate-related financial risks. Expected outcomes are targeted reform proposals to benefit policymakers and the environment by fostering private financing of clean energy.Read moreRead less
A landfill cover that generates electricity: a Microbial Fuel Cell application. Landfills account for over two per cent of Australia’s greenhouse emissions, dominating emissions from waste and wastewater. Methane emissions are inherent to landfills because waste cannot be permanently sealed until a landfill cell is full. In this project, a microbial fuel cell (MFC) landfill cover will be developed as a means of achieving full biogas capture, from the time that waste is placed. The MFC cover syst ....A landfill cover that generates electricity: a Microbial Fuel Cell application. Landfills account for over two per cent of Australia’s greenhouse emissions, dominating emissions from waste and wastewater. Methane emissions are inherent to landfills because waste cannot be permanently sealed until a landfill cell is full. In this project, a microbial fuel cell (MFC) landfill cover will be developed as a means of achieving full biogas capture, from the time that waste is placed. The MFC cover system would consist of a relatively thin and deformable granular graphite layer colonised by current generating methane oxidising microorganisms, overlain by a proton exchange membrane and steel mesh as the anode layer. The MFC cover will provide the benefit of power generation as well as more complete greenhouse gas mitigation. Read moreRead less
Unravelling the dynamics of nitrous oxide production in wastewater systems. This project aims to unravel the dynamics of Nitrous oxide (N2O) production in wastewater treatment systems by combining continuous stable isotope tracing techniques with innovative experimental design and sophisticated mathematical modelling. Nitrous oxide (N2O) is a potent greenhouse gas and a major contributor to the carbon footprint of wastewater treatment systems. Yet we have a poor understanding of how it is produc ....Unravelling the dynamics of nitrous oxide production in wastewater systems. This project aims to unravel the dynamics of Nitrous oxide (N2O) production in wastewater treatment systems by combining continuous stable isotope tracing techniques with innovative experimental design and sophisticated mathematical modelling. Nitrous oxide (N2O) is a potent greenhouse gas and a major contributor to the carbon footprint of wastewater treatment systems. Yet we have a poor understanding of how it is produced in such systems. The outcomes of this project will benefit Australian water utilities by helping them to reduce N2O emissions.Read moreRead less