Understanding The Origins Of Diabetes And Kidney Disease In Aboriginal Children And Their Mothers
Funder
National Health and Medical Research Council
Funding Amount
$1,784,613.00
Summary
Aboriginal people experience increased rates of diabetes and kidney disease than non-Aboriginal Australians. This project seeks to understand the role played by the intrauterine events, maternal nutrition, breastfeeding and early growth in the development of diabetes and kidney failure in both Aboriginal mothers and their children.
Understanding Burn Injuries In Aboriginal And Torres Strait Islander Children: Treatment, Access To Services And Outcomes.
Funder
National Health and Medical Research Council
Funding Amount
$911,798.00
Summary
This is the first large scale study to systematically examine the burden of burn injury in Aboriginal and Torres Strait Islander children, including care and cost of treatment, and relationship between access to treatment and functional outcomes. With a team comprising epidemiologists, burns clinicans and Aboriginal health researchers, this study will generate important new research evidence to improve care in this over-represented and vulnerable population.
RNA-based analysis for prediction of islet death in diabetes. Death of insulin-producing cells is a common feature in diabetes. Presently, a blood glucose test remains the only blunt instrument to diagnose diabetes. The RNA-based analysis for prediction of islet death in diabetes (RAPID) study links with eight clinical trials to test this newly developed non-invasive assay for predicting diabetes. Early diagnosis will help to reduce diabetic complications in later life.
Vitamin D, Bone Loss, Fracture And Mortality Outcome
Funder
National Health and Medical Research Council
Funding Amount
$408,736.00
Summary
Vitamin D most commonly from sunlight exposure is considered an important determinant of health, including the liability to falls and fractures; not only in the elderly but in adulthood in general. This study aims to distinguish if low vitamin D levels cause adverse health outcomes or relate to ill health, limited sunlight exposure and nutritional change. Only if low vitamin D level is causative of ill health does replacement make good public health sense.
Defining the molecular and cellular mechanisms of beta cell dysfunction. This project will investigate the influence of environment in the functional adaptation and maladaptation of pancreatic beta cells in diabetes. The research will define the molecular and cellular mechanisms linking environmental triggers such as obesity, high fatty acid levels and hyperglycaemia to beta cell dedifferentiation and dysfunction.
Ginger-based agents for delaying the onset of metabolic syndrome: type-2 diabetes and dyslipidemia. We will determine the potential of ginger, a relatively safe and popular food and spice, to be developed as a preventative nutraceutical agent to delay the onset of type 2 diabetes and its complications. Our research will allow us to formulate a standardised ginger preparation of known mechanism of action that delivers safe and reproducible effects The project has the capacity to reduce the debili ....Ginger-based agents for delaying the onset of metabolic syndrome: type-2 diabetes and dyslipidemia. We will determine the potential of ginger, a relatively safe and popular food and spice, to be developed as a preventative nutraceutical agent to delay the onset of type 2 diabetes and its complications. Our research will allow us to formulate a standardised ginger preparation of known mechanism of action that delivers safe and reproducible effects The project has the capacity to reduce the debilitating effects of type 2 diabetes in the nation's health and its high economic costs, and to improve the quality of life of the Australian community, more than 1 million of whom are affected by this growing epidemic.Read moreRead less
Achieving true representation of Indigenous people in nursing and midwifery. This project aims to address an absence of true representation of Aboriginal and Torres Strait Islander peoples and knowledges in nursing and midwifery. Significantly it intends to co-create an Aboriginal and Torres Strait Islander nurse and midwife theory and principles for practice. An anticipated goal of the research is to better understand how the theory and practice can be implemented in nurse and midwifery educati ....Achieving true representation of Indigenous people in nursing and midwifery. This project aims to address an absence of true representation of Aboriginal and Torres Strait Islander peoples and knowledges in nursing and midwifery. Significantly it intends to co-create an Aboriginal and Torres Strait Islander nurse and midwife theory and principles for practice. An anticipated goal of the research is to better understand how the theory and practice can be implemented in nurse and midwifery education (inclusive of clinical settings) in regional and urban areas. The intended outcome is to provide improved cultural safety in nursing and midwifery, greater cultural safety for health consumers and; stronger recruitment and retention of Indigenous nurses and midwives.
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Non-invasive Detection Of Hypoglycaemia In People With Diabetes Using Brain Wave Activity
Funder
National Health and Medical Research Council
Funding Amount
$330,447.00
Summary
Hypoglycaemia remains a major cause of morbidity and mortality in people with both type 1 diabetes and type 2 diabetes who require insulin therapy. Current treatments for nocturnal hypoglycaemia are usually ineffective. Combining brain wave recording and artificial intelligence, we will identify the changes that precipitate an episode of hypoglycaemia allowing the development of a non-invasive device to prevent or alleviate these fearful and potentially life-threatening events.
Centre Of Research Excellence (CRE) In Partnership Pathways To Better Care And Outcomes For Aboriginal Young People
Funder
National Health and Medical Research Council
Funding Amount
$2,497,872.00
Summary
Childhood and adolescence is a critical period during which chronic disease in Indigenous Australians can be prevented. Using long-term data and established partnerships developed over 10-15 years from two large studies of young Aboriginal people, this team of Indigenous and non-Indigenous researchers with expertise in child health, epidemiology, health services research, and implementation science will identify and test pathways to improved care and health outcomes for young Aboriginal people.
Co-designing a Food Sovereignty Model with Indigenous Communities. Food sovereignty asserts the rights of people and communities to healthy and culturally appropriate foods through determination of their own food and agriculture systems. With food insecurity higher among Indigenous households; a food sovereignty approach offers the potential for sustainable long-term solutions that maintain human dignity and reinvigorate knowledge systems. Drawing on national and international perspectives and u ....Co-designing a Food Sovereignty Model with Indigenous Communities. Food sovereignty asserts the rights of people and communities to healthy and culturally appropriate foods through determination of their own food and agriculture systems. With food insecurity higher among Indigenous households; a food sovereignty approach offers the potential for sustainable long-term solutions that maintain human dignity and reinvigorate knowledge systems. Drawing on national and international perspectives and using Indigenous research methodologies, this project aims to co-design a food sovereignty model that will enable Indigenous communities to effectively address food insecurity according to their local contexts. Both the process and solutions will contribute to improvements in physical, mental and social wellbeing.Read moreRead less