Risk Factors For Food Allergy And The Allergic March To Asthma In Childhood: The HealthNuts Study
Funder
National Health and Medical Research Council
Funding Amount
$1,876,796.00
Summary
Food allergy appears to represent a second epidemic of allergic disease. It is not known why some children grow out of their food allergy or how food allergy in the first year of life impacts asthma and allergy in later childhood. HealthNuts is a large study of 5300 children that can answer these questions. HealthNuts visited children at ages 1, 4 and 6 and requests funding to re-visit them at age 10. Results will help prevent children developing food allergy, asthma and the allergic march.
Early Introduction Of Dietary Allergen To Reduce The Population Prevalence Of Infant Food Allergy
Funder
National Health and Medical Research Council
Funding Amount
$412,468.00
Summary
Australia has the highest recorded prevalence of childhood peanut allergy, a potentially life-threatening condition. New evidence shows introducing peanut into the diet in infancy can reduce the risk of developing peanut allergy in high risk infants, and allergy prevention guidelines now recommend giving peanut before 12 months. This study will evaluate how effective these guidelines have been in promoting earlier peanut introduction and reducing the population prevalence of peanut allergy.
Perinatal Exposure To Household And Environmental Toxins And The Risk Of Asthma And Allergic Disease Up To 25 Years
Funder
National Health and Medical Research Council
Funding Amount
$291,078.00
Summary
Perinatal exposure to household and environmental toxins may increase asthma and allergic disease risk. Adverse exposures in this critical developmental window may have a marked and prolonged effect on health. A birth cohort of high-allergy risk children will be used to investigate the effect of common chemical exposures on the risk of asthma and allergic disease up to 25 years. This evidence could be used to inform guidelines on common household chemical exposures
The Role Of Infant Food Allergy In The Natural History And Burden Of Allergic Disease Across The Early Years: The HealthNuts Study
Funder
National Health and Medical Research Council
Funding Amount
$1,722,373.00
Summary
The HealthNuts study of 4600 infants is the world’s first comprehensive population-based study of food allergy with objective measurement of true food allergy and will enable us to understand better the natural history of allergic disorders including food allergy, asthma, eczema and allergic rhinitis and the interplay of risk factors for development of these conditions in the first 6 years of life. The study will have important implications for clinical guidelines and public health policy.
Prevalence Of Challenge-proven Food Allergy And Predictors Of Severe Adverse Reactions To Food In Early Adolescence: SchoolNuts
Funder
National Health and Medical Research Council
Funding Amount
$1,196,852.00
Summary
Food allergy (FA) has risen to epidemic proportions in recent times and Australia has one of the highest rates in the world. FA is most common in children under 5 years, yet adolescents are at the greatest risk of death from food-related anaphylaxis. We don’t know why this is the case. Our research will describe FA prevalence and will assess the factors placing FA adolescents at high risk of severe allergic reactions. Findings will influence policy for management of FA and anaphylaxis.
What Are The Lifetime Clinical Predictors And Risk Factors For Multiple Phenotypes Of Adult Asthma, COPD And Sleep Disordered Breathing? Following Up The TAHS Cohort From 1st To 6th Decade
Funder
National Health and Medical Research Council
Funding Amount
$1,950,689.00
Summary
Breathing gets impaired and impact on the productivity and quality of life when chronic respiratory diseases rise with ageing. Adult chronic respiratory diseases are major causes of illness and death but there are still many gaps in knowledge on how best to prevent and manage these diseases. The proposed program will provide evidence to guide health policy and clinical management of these diseases. These original findings will be of great importance both nationally and internationally.