Special Research Initiatives - Grant ID: SR180100005
Funder
Australian Research Council
Funding Amount
$1,225,000.00
Summary
Remediation of PFAS contaminated soil using soil washing and immobilisation. This project aims to assess the applicability of soil washing and immobilisation as cost-effective techniques for the remediation of per- and poly-fluroalkyl substance (PFAS) contaminated Australian soils. The project expects to establish the efficacy of the remediation of a range of PFASs, including many polyfluorinated precursors of perfluorinated, chemically-persistent legacy pollutants which are of concern. The proj ....Remediation of PFAS contaminated soil using soil washing and immobilisation. This project aims to assess the applicability of soil washing and immobilisation as cost-effective techniques for the remediation of per- and poly-fluroalkyl substance (PFAS) contaminated Australian soils. The project expects to establish the efficacy of the remediation of a range of PFASs, including many polyfluorinated precursors of perfluorinated, chemically-persistent legacy pollutants which are of concern. The project will provide a scientific basis for understanding the benefits and limitations associated with soil washing and immobilisation techniques and a more comprehensive understanding of future liabilities associated with formation of PFASs from precursors remaining in remediated soils. Collaboration with stakeholders will ensure benefits are captured both commercially and environmentally, as well as removing a potential and on-going health threat to communities exposed to these contaminants.Read moreRead less
Pushing the Boundaries of Multi-modal Biospectroscopic Microscopies. In order to understand the fundamentals of life processes, diseases, and their treatments, it is essential to probe fundamental changes in molecular processes in cells, tissues and whole organisms. Much of our understanding of these processes has involved the introduction of chemical probes for biospectroscopy, but these have inherent problems because the probe can often change the biochemistry that is being probed. This projec ....Pushing the Boundaries of Multi-modal Biospectroscopic Microscopies. In order to understand the fundamentals of life processes, diseases, and their treatments, it is essential to probe fundamental changes in molecular processes in cells, tissues and whole organisms. Much of our understanding of these processes has involved the introduction of chemical probes for biospectroscopy, but these have inherent problems because the probe can often change the biochemistry that is being probed. This project will push the boundaries of a variety of micro and nano "probe-free" microscopies to provide fundamental insights into these life processes, which could ultimately lead to improvements in the diagnosis, prevention and treatment of diseases.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100040
Funder
Australian Research Council
Funding Amount
$4,997,903.00
Summary
ARC Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB). The Centre for Facilitated Advancement of Australia's Bioactives (FAAB) will transform the rapidly growing bioactive ingredients sector. It will apply advanced analytical methods to molecular characterisation of bioactive products derived from foods, food-waste, and cell-based biotechnologies. FAAB will determine modes of action for bioactives with potential lifestyle and nutritional benefits allowing for evidence- ....ARC Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB). The Centre for Facilitated Advancement of Australia's Bioactives (FAAB) will transform the rapidly growing bioactive ingredients sector. It will apply advanced analytical methods to molecular characterisation of bioactive products derived from foods, food-waste, and cell-based biotechnologies. FAAB will determine modes of action for bioactives with potential lifestyle and nutritional benefits allowing for evidence-informed decision-making, and regulatory framework development. FAAB graduates will lead and deliver future national self-reliance to the Australian bioactives sector, increasing diversification and international competitiveness and development of regulation in a growing market. Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100056
Funder
Australian Research Council
Funding Amount
$3,975,864.00
Summary
ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning an ....ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning and artificial intelligence for the delivery of optimal solutions in diagnosis, treatment and wellbeing. The centre will deliver training in Industry 4.0 skills which will boost early-stage scale-up and accelerate the sector’s supply chain, which is pivotal for the Australian industries to maintain a competitive edge. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346515
Funder
Australian Research Council
Funding Amount
$507,000.00
Summary
Fluorescence Detector for the Australian National Beamline Facility. X-ray absorption spectroscopy (XAS) is an extremely important synchrotron radiation tool for determining the local structure around an X-ray absorbing atom. This has many applications in the study of materials, minerals, metal complexes, and metalloproteins and can often be used to obtain information that is not available by other techniques, because structural information can be obtained in the solid or solution state and in ....Fluorescence Detector for the Australian National Beamline Facility. X-ray absorption spectroscopy (XAS) is an extremely important synchrotron radiation tool for determining the local structure around an X-ray absorbing atom. This has many applications in the study of materials, minerals, metal complexes, and metalloproteins and can often be used to obtain information that is not available by other techniques, because structural information can be obtained in the solid or solution state and in mixtures. The current proposal is aimed at introducing new technology into the Australian National Beamline Facility that will greatly improve the quality and quantity of experiments that can be performed and extend studies into dilute solutions and protein samples.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100236
Funder
Australian Research Council
Funding Amount
$180,000.00
Summary
Facilities for spectroscopy and diffraction at high pressures. The provision of infrastructure for the study of novel materials under high pressures will enhance Australia's capability in creating new materials and in creating new devices that meet needs in communication, environment and medicine applications. The new facility will enable researchers to understand the response of structures to extreme pressures and will exploit the unique capabilities of the synchrotron light.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0883078
Funder
Australian Research Council
Funding Amount
$356,000.00
Summary
Liquid Chromatography Tandem Mass Spectrometry Steroid Analysis Facility. This first of a new generation of ultra-sensitive analytical mass spectrometers for small molecules will be established as a national assay facility allowing all Australian researchers open access to a new dimension of highly accurate and simultaneous measurements of multiple bodily chemicals such as steroids, vitamins and hormones. It is crucial to developing new knowledge in basic, developmental and pathological cell bio ....Liquid Chromatography Tandem Mass Spectrometry Steroid Analysis Facility. This first of a new generation of ultra-sensitive analytical mass spectrometers for small molecules will be established as a national assay facility allowing all Australian researchers open access to a new dimension of highly accurate and simultaneous measurements of multiple bodily chemicals such as steroids, vitamins and hormones. It is crucial to developing new knowledge in basic, developmental and pathological cell biology and for underpinning commercial developments of new molecular targets for therapeutic drugs for many diseases including cancer, cardiovascular disease and reproductive disorders. This facility is pivotal to maintaining international competitiveness in many areas of biological research in national priority areas.Read moreRead less
A new molecular platform for catalytic synthesis of heterocycles. This project aims to address the lack of efficient methods to prepare cyclic molecules of biological relevance by utilising novel molecular platforms developed in our laboratories. This project expects to generate new cyclic molecules using these innovative molecular platforms by employing catalysts to reduce raw material and energy cost. The expected outcomes of this project include enhanced chemical technology to prepare cyclic ....A new molecular platform for catalytic synthesis of heterocycles. This project aims to address the lack of efficient methods to prepare cyclic molecules of biological relevance by utilising novel molecular platforms developed in our laboratories. This project expects to generate new cyclic molecules using these innovative molecular platforms by employing catalysts to reduce raw material and energy cost. The expected outcomes of this project include enhanced chemical technology to prepare cyclic molecules of pharmaceutical importance and the training of highly skilled PhD students. This should provide significant benefits, such as increased capacity for the development of new pharmaceuticals and advanced materials.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100060
Funder
Australian Research Council
Funding Amount
$563,390.00
Summary
Shared picosecond-laser facility. This project aims to extend the Shared Picosecond Laser Facility to include picosecond-pulse technology and to incorporate new consortium members. The Facility, shared among members at four universities and building on over 23 years of collaboration, continues to provide access to state-of-the-art lasers. The Facility will take advantage of its bulk purchasing power to negotiate significant discounts, extended warranties and maintenance contracts. The new lasers ....Shared picosecond-laser facility. This project aims to extend the Shared Picosecond Laser Facility to include picosecond-pulse technology and to incorporate new consortium members. The Facility, shared among members at four universities and building on over 23 years of collaboration, continues to provide access to state-of-the-art lasers. The Facility will take advantage of its bulk purchasing power to negotiate significant discounts, extended warranties and maintenance contracts. The new lasers will enable access to picosecond timescales and facilitate complex multi-laser experiments in a wide variety of projects including reaction dynamics, materials chemistry and photovoltaics.Read moreRead less
Self-zoning in natural uraninite: radiation driven chemical separation. In this project we aim to explore and define the effects of the substitution of lead and rare earths on the crystal chemistry of uranium dioxide (uraninite) and related minerals, towards establishing the oxygen stoichiometry (as a measure of oxygen fugacity) of these materials both in nature and in synthetic materials. This project will use synthetic materials to understand the variability of oxygen stoichiometry, establish ....Self-zoning in natural uraninite: radiation driven chemical separation. In this project we aim to explore and define the effects of the substitution of lead and rare earths on the crystal chemistry of uranium dioxide (uraninite) and related minerals, towards establishing the oxygen stoichiometry (as a measure of oxygen fugacity) of these materials both in nature and in synthetic materials. This project will use synthetic materials to understand the variability of oxygen stoichiometry, establish accurate and precise structures for the oxides, and distinguish both long range and short-range order which is critical to understanding both natural and synthetic U-oxides. This will help to define the geochemical conditions leading to the formation of deposits like Olympic Dam towards potential economic benefit.Read moreRead less