Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775725
Funder
Australian Research Council
Funding Amount
$465,000.00
Summary
Molecular separation and characterisation - A facility for advanced mass spectroscopy and chromatography. Characterising molecular composition is a basic need for the progress of many sciences. It is used to examine traditional and modern medicinal chemistry, bio-active peptides, molecular modulation of chemical properties, markers of disease and system status, and can also be used to elucidate molecular mechanisms and interactions in a system. This can only be achieved through precise measureme ....Molecular separation and characterisation - A facility for advanced mass spectroscopy and chromatography. Characterising molecular composition is a basic need for the progress of many sciences. It is used to examine traditional and modern medicinal chemistry, bio-active peptides, molecular modulation of chemical properties, markers of disease and system status, and can also be used to elucidate molecular mechanisms and interactions in a system. This can only be achieved through precise measurement using the frontier technologies described in this grant. This proposal ensures international competitiveness on a broad front, and supports highest level research training and bio/chemical/medical research in several priority research areas. Read moreRead less
Special Research Initiatives - Grant ID: SR0354560
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
AUSTRALIAN RESEARCH NETWORK IN ANALYTICAL SCIENCE (ARNAS). The initiative will provide the foundations for the establishment of an Australian Research Network in Analytical Science (ARNAS), which will bring together fundamental researchers and practitioners working in quantitative chemical analysis and related areas. ARNAS will provide national coordination of research in analytical science, coverage of the newest developments, pooling of expertise and research facilities and resources, and rap ....AUSTRALIAN RESEARCH NETWORK IN ANALYTICAL SCIENCE (ARNAS). The initiative will provide the foundations for the establishment of an Australian Research Network in Analytical Science (ARNAS), which will bring together fundamental researchers and practitioners working in quantitative chemical analysis and related areas. ARNAS will provide national coordination of research in analytical science, coverage of the newest developments, pooling of expertise and research facilities and resources, and rapid dissemination of outcomes. ARNAS will significantly advance the national research agenda for analytical science by improving awareness of research activities and expertise, providing enhanced education and opportunities for the next generation of analytical scientists, and by stimulating new international collaborations.Read moreRead less
Immobilised Lipid Chromatography for Membrane Protein Isolation and Analysis. Current techniques for membrane protein are inadequate for the emerging proteomic challenge, in which approximately 40% of proteins are predicted to be membrane associated. The aim of this proposal is to develop a new approach to purify membrane proteins using our recently-developed immobilised membrane chromatography materials. The present proposal will provide a new high-resolution separation technique that allows is ....Immobilised Lipid Chromatography for Membrane Protein Isolation and Analysis. Current techniques for membrane protein are inadequate for the emerging proteomic challenge, in which approximately 40% of proteins are predicted to be membrane associated. The aim of this proposal is to develop a new approach to purify membrane proteins using our recently-developed immobilised membrane chromatography materials. The present proposal will provide a new high-resolution separation technique that allows isolation and on-line mass analysis of complex mixtures of membrane proteins for subsequent proteomic analysis, high-throughput screening or structural studies and could form the basis for further development of new commercial tools for membrane protein analysis.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989491
Funder
Australian Research Council
Funding Amount
$172,025.00
Summary
Multi-Purpose Mass Spectrometry Facility. The Australian Centre for Research on Separation Science (ACROSS) has been established using focused research themes to provide both fundamental and applied research outcomes in separation science. The requested Time of Flight Mass Spectrometer (TOFMS) will be utilised extensively by a large team of researchers working across the broad areas of analytical chemistry, pharmaceutical science, materials science, biochemistry, microfluidics, industrial chemi ....Multi-Purpose Mass Spectrometry Facility. The Australian Centre for Research on Separation Science (ACROSS) has been established using focused research themes to provide both fundamental and applied research outcomes in separation science. The requested Time of Flight Mass Spectrometer (TOFMS) will be utilised extensively by a large team of researchers working across the broad areas of analytical chemistry, pharmaceutical science, materials science, biochemistry, microfluidics, industrial chemistry and hydrometallurgy, aquaculture, forensic analysis, Antarctic studies, and environmental monitoring. This will directly support our work falling under National Research Priorities 1 An Environmentally Sustainable Australia, 2 Promoting and Maintaining Good Health, 3 Frontier Technologies for Building and Transforming Australian Industries, and 4 Safeguarding Australia.Read moreRead less
Advanced Separation Technologies and Chemometric Data Processing for Macromolecular Materials and Metabolite Profiling. The project will develop innovative separation technologies for specialised materials, which could lead the scientific export industry in Australia, with employment benefits to the community. Partner, Dow has links with researchers around the world, and this project will allow Australian researchers to access the network of Dow laboratories and projects and develop a long-term ....Advanced Separation Technologies and Chemometric Data Processing for Macromolecular Materials and Metabolite Profiling. The project will develop innovative separation technologies for specialised materials, which could lead the scientific export industry in Australia, with employment benefits to the community. Partner, Dow has links with researchers around the world, and this project will allow Australian researchers to access the network of Dow laboratories and projects and develop a long-term relationship. The analysis methods to be developed will focus on metabolite profiling which has relevance to a broad range of biological monitoring activities from human health, to plant genetics and breeding. New generation polymer materials will be characterised by using the new techniques developed. The methods will be platform technologies for future studies eg. anti-terrorism bio- and chemo-monitoring.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100140
Funder
Australian Research Council
Funding Amount
$275,000.00
Summary
Quarantined ion chromatography mass spectrometry (IC-MS) facility. This proposal seeks to establish a quarantined facility for 'ion chromatography-mass spectrometry', to provide high resolution ion chromatographic and mass spectrometric analytical capability to the environmental, analytical/bioanalyical, and industrial science research communities. The state-of-the-art facility will represent the only quarantined high-resolution IC-MS facility within Australia, and therefore not only support the ....Quarantined ion chromatography mass spectrometry (IC-MS) facility. This proposal seeks to establish a quarantined facility for 'ion chromatography-mass spectrometry', to provide high resolution ion chromatographic and mass spectrometric analytical capability to the environmental, analytical/bioanalyical, and industrial science research communities. The state-of-the-art facility will represent the only quarantined high-resolution IC-MS facility within Australia, and therefore not only support the above communities within Australia, but the potential to facilitate research collaboration internationally, including supporting Australia's leading Antarctic Science programs. Read moreRead less
Novel semio-chemical approach to control the Australian Sheep Blowfly . The Australian Federal Government through the 'Smart Farming' initiative highlights the need for improved multidisciplinary measures in order to remain at the global forefront of the invention and adoption of technology. This multidisciplinary project (entomology, biotechnology, analytical chemistry and genomics) will rapidly inform the management of fly strike on an important Australian resource merino sheep. This will bui ....Novel semio-chemical approach to control the Australian Sheep Blowfly . The Australian Federal Government through the 'Smart Farming' initiative highlights the need for improved multidisciplinary measures in order to remain at the global forefront of the invention and adoption of technology. This multidisciplinary project (entomology, biotechnology, analytical chemistry and genomics) will rapidly inform the management of fly strike on an important Australian resource merino sheep. This will build the key biochemical data in order to develop a novel fly lure technology (at scale) to be used on farm delivering national benefit through improved animal welfare and safety considerations for producers, and will establish the best approach to disseminate this scientific information to stakeholders such as farmers.Read moreRead less
Enhancing Selectivity and Detection in Miniaturised Analytical Separation Systems. Miniaturisation-compatible stationary phases and detection techniques will be developed for microseparation techniques of capillary electrochromatography and chip-based separation systems, and their analytical applications will be investigated. Replaceable stationary phases (RSP) of chromatographic particles suspended in reversible gels will be created by delivering a liquid RSP to the column followed by in situ ....Enhancing Selectivity and Detection in Miniaturised Analytical Separation Systems. Miniaturisation-compatible stationary phases and detection techniques will be developed for microseparation techniques of capillary electrochromatography and chip-based separation systems, and their analytical applications will be investigated. Replaceable stationary phases (RSP) of chromatographic particles suspended in reversible gels will be created by delivering a liquid RSP to the column followed by in situ immobilisation. This approach offers flexibility in optimising a number of parameters of the column and of its use for sample pre-treatment and preconcentration. Pulsed potentiometric detection will be developed for the abovementioned microseparation techniques, combining the advantages of pulsed amperometric techniques with the more universally responding potentiometric detection.Read moreRead less
The Synthesis and Analysis of Certain Explosives and Illicit Drugs for Improved Forensic Detection. There is an increasing demand within law enforcement agencies, worldwide, for selective and sensitive methods for the determination of illicit substances. Over the last decade Deakin University chemists have played a major role in establishing the utility of chemiluminescent reactions for the determination of a variety of pharmaceutical opiates in process streams. This project seeks to build upon ....The Synthesis and Analysis of Certain Explosives and Illicit Drugs for Improved Forensic Detection. There is an increasing demand within law enforcement agencies, worldwide, for selective and sensitive methods for the determination of illicit substances. Over the last decade Deakin University chemists have played a major role in establishing the utility of chemiluminescent reactions for the determination of a variety of pharmaceutical opiates in process streams. This project seeks to build upon these successes, in order to develop innovative analytical strategies for forensic detection of certain illicit drugs and explosives. The results of this research have the potential to revolutionise key aspects of forensic analysis.Read moreRead less
Simulation, Modelling, Prediction and Two-Dimensional Retention Database Development in Comprehensive Two-Dimensional Gas Chromatography (GC×GC). Quality of life is enhanced by the application of chromatography to many aspects of living. It is an existing technology made more powerful when used as comprehensive two-dimensional gas chromatography (GC×GC), an advanced form of GC. This project will apply new interpretation strategies to GC×GC to improve precise chemical analysis in many areas inclu ....Simulation, Modelling, Prediction and Two-Dimensional Retention Database Development in Comprehensive Two-Dimensional Gas Chromatography (GC×GC). Quality of life is enhanced by the application of chromatography to many aspects of living. It is an existing technology made more powerful when used as comprehensive two-dimensional gas chromatography (GC×GC), an advanced form of GC. This project will apply new interpretation strategies to GC×GC to improve precise chemical analysis in many areas including: measurement of 'good fats' in foods, sources of illicit drugs, allergens in perfumes, disease profiling through metabolite monitoring and the detection of performance enhancing drugs in sport. Based on this research, the science of chromatography will be advanced in Australia and throughout the world, using Australian technology and expertise.Read moreRead less