An integrated genomics approach to improve our understanding of the biology of genital campylobacteriosis in beef cattle. Beef is Australia's most valuable agricultural export estimated at $9.6B annually and this industry accounts for one-third of full time employment in regional communities. Currently, unknown causes of reproductive losses in cattle in Northern Australian cost producers approximately $15M per annum. Bovine genital campylobacteriosis is one of the major risk factors associated w ....An integrated genomics approach to improve our understanding of the biology of genital campylobacteriosis in beef cattle. Beef is Australia's most valuable agricultural export estimated at $9.6B annually and this industry accounts for one-third of full time employment in regional communities. Currently, unknown causes of reproductive losses in cattle in Northern Australian cost producers approximately $15M per annum. Bovine genital campylobacteriosis is one of the major risk factors associated with this high cost due to the inability to accurately diagnose the disease. This research will integrate genomics and bioinformatics with infection and vaccination models to improve our understanding of the biology of the disease to develop appropriate control strategies securing Australia's beef industry.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100016
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre in Predictive Breeding for Agricultural Futures. This Centre aims to develop the advanced capacity needed to secure Australia’s food and fibre production and export value into the future. Leveraging immense industry support, the Centre expects to develop and integrate cutting-edge plant and animal breeding technologies and deliver world-class training that addresses critical demand for highly skilled industry leaders. Expected outcomes include a future-ready predictive breedi ....ARC Training Centre in Predictive Breeding for Agricultural Futures. This Centre aims to develop the advanced capacity needed to secure Australia’s food and fibre production and export value into the future. Leveraging immense industry support, the Centre expects to develop and integrate cutting-edge plant and animal breeding technologies and deliver world-class training that addresses critical demand for highly skilled industry leaders. Expected outcomes include a future-ready predictive breeding industry able to transform data into optimised decisions, and the human capacity to drive it. This should provide significant benefits to enhance the sustainability and profitability of all major Australian agriculture sectors, including livestock, grains, horticulture, cotton, wine, dairy, forestry and fisheries.Read moreRead less
High Penetrance Deleterious Mutations In Blinding Glaucoma
Funder
National Health and Medical Research Council
Funding Amount
$1,345,055.00
Summary
This project aims to identify the genes most commonly mutated in individuals with advanced glaucoma. Identification of such genes will lead to improved understanding of glaucoma pathogenesis, a better ability to predict risk, and the identification of drug targets for novel therapies.
Utilising novel Pongamia trees to decarbonise Australia’s beef value-chain. Progress towards a carbon neutral beef industry typically focusses on nutritional strategies, overlooking potential innovations in farming system configuration. This project aims to develop a framework for the integration of Pongamia into beef production systems, so that not only emissions reductions are maximised, but also to support carbon capture and farm system resilience. This project seeks to determine the impact o ....Utilising novel Pongamia trees to decarbonise Australia’s beef value-chain. Progress towards a carbon neutral beef industry typically focusses on nutritional strategies, overlooking potential innovations in farming system configuration. This project aims to develop a framework for the integration of Pongamia into beef production systems, so that not only emissions reductions are maximised, but also to support carbon capture and farm system resilience. This project seeks to determine the impact of Pongamia meal on cattle production efficiency, meat quality and methane emissions. Through quantification of carbon sequestration potential in tree plantations, whole-farm modelling will elucidate production scenarios capable of achieving the reductions needed for a carbon neutral Australian beef industry.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100050
Funder
Australian Research Council
Funding Amount
$4,508,426.00
Summary
ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR). The ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance aims to develop industry-led solutions and train a new generation of researchers to combat the impact of antimicrobial resistance (AMR) on agribusiness and the environment.
AMR is a global health and economic threat that epitomises the need for a ‘One Health’ collaborative approach encompassi ....ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR). The ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance aims to develop industry-led solutions and train a new generation of researchers to combat the impact of antimicrobial resistance (AMR) on agribusiness and the environment.
AMR is a global health and economic threat that epitomises the need for a ‘One Health’ collaborative approach encompassing the interconnection between people, animals, plants, and their shared environment.
Expected outcomes of this collaborative program include a cohort of researchers trained in industry-relevant techniques, furnishing solutions to partner-defined AMR challenges, and providing significant benefits by positioning Australia as a global leader in reducing AMR.Read moreRead less
Deep Downunder: designing a deep-sea exploration and discovery capability for Australia. Exploration of the deep-sea with the modern technologies to be developed by Deep-Downunder is a first for Australia. We aim to explore and discover life at depths from 50-3000m off The Great Barrier Reef, around the seamounts of Lord Howe Island and Tasmania and in the deep canyons of WA and SA. We expect to discover new species, hope for a glimpse of giant squid at home and will answer specific questions on ....Deep Downunder: designing a deep-sea exploration and discovery capability for Australia. Exploration of the deep-sea with the modern technologies to be developed by Deep-Downunder is a first for Australia. We aim to explore and discover life at depths from 50-3000m off The Great Barrier Reef, around the seamounts of Lord Howe Island and Tasmania and in the deep canyons of WA and SA. We expect to discover new species, hope for a glimpse of giant squid at home and will answer specific questions on Australia's ocean biology, fisheries and biotechnology never before approachable. To be effective guardians of Australian waters we must learn what lies in the depths we can't see from a boat.Read moreRead less
Assessing the determinants and consequences of safety climate in the maritime industry. This project will examine the predictors and outcomes of safety climate in the Australian maritime industry. Findings from this project will be used to improve safety policies, regulations and practices that aim to minimise the number of accidents and incidents in Australian waters.
Understanding specificity and flexibility in coral symbioses. This project aims to understand why some corals can switch algal partners while others remain faithful to a single strain. This is important because corals depend on their symbiotic algal partners for survival and because some algae provide greater resilience to environmental stress than others. This project will greatly enhance our understanding of the molecular and physiological factors governing flexibility and specificity in coral ....Understanding specificity and flexibility in coral symbioses. This project aims to understand why some corals can switch algal partners while others remain faithful to a single strain. This is important because corals depend on their symbiotic algal partners for survival and because some algae provide greater resilience to environmental stress than others. This project will greatly enhance our understanding of the molecular and physiological factors governing flexibility and specificity in coral-algal symbioses. It will provide much-needed knowledge required to identify associations most appropriate for specific conditions, prioritise populations for conservation, and assess the feasibility of new approaches to managing and restoring coral reefs.
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Understanding mosquito smell system: a new frontier in mosquito control. This project aims to identify and functionally investigate mosquito smell receptors, which are critical in detecting volatile compounds and locating their hosts from a considerable distance away. Mosquitoes display preferences for certain hosts over others, primarily determined by volatile chemicals produced by hosts. This study builds on recently discovered, novel, host-derived volatile compounds, which can elicit robust r ....Understanding mosquito smell system: a new frontier in mosquito control. This project aims to identify and functionally investigate mosquito smell receptors, which are critical in detecting volatile compounds and locating their hosts from a considerable distance away. Mosquitoes display preferences for certain hosts over others, primarily determined by volatile chemicals produced by hosts. This study builds on recently discovered, novel, host-derived volatile compounds, which can elicit robust responses and attractiveness from mosquitoes. Expected outcomes of the project are enhanced understanding of mosquito smell system and behaviours. This could provide significant benefits to how we can fight mosquitoes and mosquito-transmitted diseases in a more efficient and environmentally responsible way.Read moreRead less
Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are inn ....Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.Read moreRead less