Special Research Initiatives - Grant ID: SR0354622
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the early embryo have major consequences for the development of individuals. The aim of this Network is to harness the resources of leading researchers from the previously distinct disciplines of developmental biology and developmental physiology to better understand developmental regulatory networks and how environmental factors impinge on them. The formation of such a Network ....Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the early embryo have major consequences for the development of individuals. The aim of this Network is to harness the resources of leading researchers from the previously distinct disciplines of developmental biology and developmental physiology to better understand developmental regulatory networks and how environmental factors impinge on them. The formation of such a Network is unique, timely and strategic in that it will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory ne ....ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory networks and to address how environmental factors impinge on these regulatory networks. The formation of this National Research Network is unique, timely and strategic. It will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
Mechanisms Of Glucocorticoid Resistance In Acute Lymphoblastic Leukaemia
Funder
National Health and Medical Research Council
Funding Amount
$547,970.00
Summary
Glucocorticoids are extremely active drugs used in the treatment of childhood acute lymphoblastic leukaemia (ALL), yet a proportion of patients respond poorly to therapy and exhibit resistance at relapse. Clinically relevant mechanisms of glucocorticoid resistance are poorly understood, principally due to lack of appropriate experimental models. This project will reveal novel mechanisms of drug resistance in childhood leukaemia and lead to novel therapeutic strategies to improve outcome.
Regional Australia' skills shortages and high-skill refugees' employment . Regional Australia loses to cities thousands of professional and trade-related people whose skills cannot be replaced. Focusing on small and medium-size enterprises producing food and beverages, this project aims to determine whether refugee employment (i) is a strategic resource (ii) can alleviate these chronic regional skill shortages, and (iii) can be integrated in immigration policy. In doing so, it will for the firs ....Regional Australia' skills shortages and high-skill refugees' employment . Regional Australia loses to cities thousands of professional and trade-related people whose skills cannot be replaced. Focusing on small and medium-size enterprises producing food and beverages, this project aims to determine whether refugee employment (i) is a strategic resource (ii) can alleviate these chronic regional skill shortages, and (iii) can be integrated in immigration policy. In doing so, it will for the first time provide critical empirical evidence on the possible need to separate policy measures aimed at rural vs. urban employers. The outcomes will contribute to reducing the problem of critical skill shortages and wastage at once and do so with an eye to the needs to rural Australia – a key driver of the country’s exports. Read moreRead less
Incentivising On Country Aboriginal Employment: Anangu Futures. . This project aims to investigate the changing face of cultural tourism in central Australia and examine pathways towards sustainable aboriginal employment in and around Uluru-Kata Tjuta National Park. The project is significant because it brings together Aboriginal community members, industry and government stakeholders to identify micro-business opportunities, youth training initiatives, better relations across cultural divides, ....Incentivising On Country Aboriginal Employment: Anangu Futures. . This project aims to investigate the changing face of cultural tourism in central Australia and examine pathways towards sustainable aboriginal employment in and around Uluru-Kata Tjuta National Park. The project is significant because it brings together Aboriginal community members, industry and government stakeholders to identify micro-business opportunities, youth training initiatives, better relations across cultural divides, and the economic value of Aboriginal knowledge. Outcomes include a model for sustainable Aboriginal employment in remote and very remote contexts, and the development of culturally relevant and sustainable governing guidelines for regional investment. Benefits include more sustainable jobs for Aboriginal people.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100174
Funder
Australian Research Council
Funding Amount
$805,000.00
Summary
Urban Analytics Data Infrastructure. Urban analytics data infrastructure:
This project aims to develop an urban analytics data infrastructure that builds on the Australian Urban Research Infrastructure Network. This digital data infrastructure intends to enable the integration, harmonisation, connectivity and scalability of multi-source urban datasets. This infrastructure is required to underpin the next generation of data-driven modelling and decision-support tools to enable the design of smar ....Urban Analytics Data Infrastructure. Urban analytics data infrastructure:
This project aims to develop an urban analytics data infrastructure that builds on the Australian Urban Research Infrastructure Network. This digital data infrastructure intends to enable the integration, harmonisation, connectivity and scalability of multi-source urban datasets. This infrastructure is required to underpin the next generation of data-driven modelling and decision-support tools to enable the design of smart, productive and resilient cities. These capabilities are predicated on the adoption of ISO standards, development of new ontological frameworks and an urban data dictionary to enable semantic inferencing of datasets and the development of data structures and services. This framework would then be applied to data relevant to people, land and urban infrastructure to support comparative and multi-dimensional analytics. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100118
Funder
Australian Research Council
Funding Amount
$1,800,000.00
Summary
UltraTEM: Resolving the structure of matter in space, energy and time. This project aims to establish a transmission electron microscope facility to analyse materials structure at the atomic level. A small number of atoms in critical locations governs the properties of materials from solar cells and catalysts to aerospace alloys, bio-sensors and quantum computers. To understand and engineer matter at this atomic level, tools are needed to characterise these critical atoms. This open access, nati ....UltraTEM: Resolving the structure of matter in space, energy and time. This project aims to establish a transmission electron microscope facility to analyse materials structure at the atomic level. A small number of atoms in critical locations governs the properties of materials from solar cells and catalysts to aerospace alloys, bio-sensors and quantum computers. To understand and engineer matter at this atomic level, tools are needed to characterise these critical atoms. This open access, national facility will be able to characterise matter at the atomic-level. Expected outcomes include better understanding of the natural world and advanced materials to solve problems in energy, technology, health, environment, communications, advanced manufacturing, transport and security.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100132
Funder
Australian Research Council
Funding Amount
$1,486,000.00
Summary
A triple beam microscope: new frontiers in materials nanocharacterisation. This project aims to establish a triple beam ion and electron microscope facility for the modification, preparation and characterisation of materials that have hitherto been too sensitive for high resolution analysis with charged particle beams. It is expected that materials will be studied artefact-free and at the nanoscale with twin ion beams and new detectors that allow novel imaging modes and extreme chemical sensitiv ....A triple beam microscope: new frontiers in materials nanocharacterisation. This project aims to establish a triple beam ion and electron microscope facility for the modification, preparation and characterisation of materials that have hitherto been too sensitive for high resolution analysis with charged particle beams. It is expected that materials will be studied artefact-free and at the nanoscale with twin ion beams and new detectors that allow novel imaging modes and extreme chemical sensitivity plus controlled atmosphere transfer to other instruments for correlative measurements. This unique facility should benefit research in many disciplines such as physics, chemistry, geology, pharmacy, materials, civil and chemical engineering by allowing first-ever observations of vital phenomena in diverse materials.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100001
Funder
Australian Research Council
Funding Amount
$875,000.00
Summary
A 3-photon imaging system for deep live imaging. This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology. This project will capitalise on advanced laser, microscope and adaptive optics technologies with the expected out ....A 3-photon imaging system for deep live imaging. This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology. This project will capitalise on advanced laser, microscope and adaptive optics technologies with the expected outcomes to include the generation of new knowledge of major biological systems, including the immune system and the nervous system. This will provide significant benefits to fundamental interdisciplinary research into immunology, infectious disease, neuroscience, mechanobiology and engineering.Read moreRead less
A longitudinal study of the interaction of home and school language in three Aboriginal communities. The importance of language skills cannot be underestimated, and contribute to 'a healthy start to life'. In multilingual Indigenous communities, children must negotiate the complexities of different languages used for different purposes. This project will provide detailed insights into how children manage differences between home and school language, the kinds of problems they encounter when the ....A longitudinal study of the interaction of home and school language in three Aboriginal communities. The importance of language skills cannot be underestimated, and contribute to 'a healthy start to life'. In multilingual Indigenous communities, children must negotiate the complexities of different languages used for different purposes. This project will provide detailed insights into how children manage differences between home and school language, the kinds of problems they encounter when they enter the school system, and how their languages develop over the first four crucial years of school which provide the foundation for the children's future education. Their ability to manage the language of school underpins their ability to lead successful and engaged lives as adults. Read moreRead less