Molecular mechanisms for seminal fluid signalling in reproduction. Male seminal fluid regulation of the female reproductive process influences fertility and fecundity in humans and animal species. Infertility and impaired reproductive function is a major economic constraint in livestock industries, and carries a substantial social and public health cost in humans. This research will identify the active signalling molecules in seminal fluid and quantify their importance in reproductive success ....Molecular mechanisms for seminal fluid signalling in reproduction. Male seminal fluid regulation of the female reproductive process influences fertility and fecundity in humans and animal species. Infertility and impaired reproductive function is a major economic constraint in livestock industries, and carries a substantial social and public health cost in humans. This research will identify the active signalling molecules in seminal fluid and quantify their importance in reproductive success and health of offspring. The outcomes will inform development of new diagnostic assays for male fertility, and underpin strategic design of novel fertility treatments and products with applications in the human health and animal breeding industries. Read moreRead less
Decoding tissue-specific components of cereal grain development. This project aims to investigate how barley flowers produce cells that deliver nutrients into developing seeds. This project expects to generate new knowledge through international collaboration and technical improvements in cell biology and genetics, overcoming current methodological limitations to precisely influence seed size, shape and quality, which are traits of agricultural relevance to the Australian cereal industry. Expect ....Decoding tissue-specific components of cereal grain development. This project aims to investigate how barley flowers produce cells that deliver nutrients into developing seeds. This project expects to generate new knowledge through international collaboration and technical improvements in cell biology and genetics, overcoming current methodological limitations to precisely influence seed size, shape and quality, which are traits of agricultural relevance to the Australian cereal industry. Expected outcomes include strengthened international partnerships, leveraged funding and increased knowledge of plant reproduction. This should provide significant benefits, including upskilled researchers, improved research capacity and genetic targets to optimise seed production in challenging climatic conditions. Read moreRead less
Network Management in a World of Secrets. The aim of this proposal is to provide world leading measurement and management techniques for the Internet and other telecommunications networks. In particular, the methods will improve privacy of network participants (customers and providers) while simultaneously improving network performance. Additionally, the project will create expertise in an area of great future interest -- privacy preserving computation -- expertise that can be transferred to stu ....Network Management in a World of Secrets. The aim of this proposal is to provide world leading measurement and management techniques for the Internet and other telecommunications networks. In particular, the methods will improve privacy of network participants (customers and providers) while simultaneously improving network performance. Additionally, the project will create expertise in an area of great future interest -- privacy preserving computation -- expertise that can be transferred to students and the next generation of innovators.
Apart from these benefits, the research will provide exposure of Australian research strength in an area of world-wide public interest. Results concerning Internet reliability are of particularly high impact. Read moreRead less
Activating the female germline during plant development. This project aims to investigate the mechanistic basis for female germline formation in two plant species including barley, which is of agricultural relevance to Australia. This project’s approach will integrate novel regulatory genes and data from Arabidopsis and barley. This knowledge will provide significant benefits, such as novel reproductive strategies for crop improvement.
How SEP-like genes determine cereal inflorescence architecture. This project aims to understand the morphological diversity of inflorescence architecture between cereal crop species. To do so, this project will identify functions and analyse the regulatory networks of conserved SEPALLATA genes (SEPs). This will enable them to determine cereal inflorescence morphogenesis of rice (branching) and barley (non-branching), representing the most important cereals. Identifying and understanding rice and ....How SEP-like genes determine cereal inflorescence architecture. This project aims to understand the morphological diversity of inflorescence architecture between cereal crop species. To do so, this project will identify functions and analyse the regulatory networks of conserved SEPALLATA genes (SEPs). This will enable them to determine cereal inflorescence morphogenesis of rice (branching) and barley (non-branching), representing the most important cereals. Identifying and understanding rice and barley SEPs, their direct targets and interactors, and how they regulate inflorescence branches and spikelets in both species is expected to provide evolutionary and developmental insights and targets to improve for crop yield. A molecular understanding of the regulatory network that underpins inflorescence shape and grain number will advance fundamental biology, and could form the basis for significant yield improvements by manipulating key points in the developmental pathway.Read moreRead less
Dissecting the impact of stress on reproduction: Novel peptide mediates inhibitory effects of stress on female reproduction. This research proposal offers a pioneering opportunity to develop treatments that overcome the negative impact of stress on reproduction. Specifically, knowledge generated in this project will be vital in the development of strategic defences against the impact of stress on reproduction. This project fundamentally addresses Research Priority 2: Promoting and maintaining go ....Dissecting the impact of stress on reproduction: Novel peptide mediates inhibitory effects of stress on female reproduction. This research proposal offers a pioneering opportunity to develop treatments that overcome the negative impact of stress on reproduction. Specifically, knowledge generated in this project will be vital in the development of strategic defences against the impact of stress on reproduction. This project fundamentally addresses Research Priority 2: Promoting and maintaining good health. Given that suppression of reproduction by stress occurs in all mammalian species including humans, domestic animals and wildlife, being able to prevent or overcome stress-induced reproductive dysfunction will generate significant health, social, economic and ecological benefits. Read moreRead less
Protecting cereal grain development at high temperatures. This project aims to investigate new temperature-responsive factors that regulate cereal grain development to protect grain production under heat stress. The new research will leverage international collaborations with access to cutting-edge genetic and technological resources, and refine novel X-ray imaging techniques in Australia, to observe how temperature affects flower structure and function in barley and rice. Favourable mutations t ....Protecting cereal grain development at high temperatures. This project aims to investigate new temperature-responsive factors that regulate cereal grain development to protect grain production under heat stress. The new research will leverage international collaborations with access to cutting-edge genetic and technological resources, and refine novel X-ray imaging techniques in Australia, to observe how temperature affects flower structure and function in barley and rice. Favourable mutations that optimise plant yield and fitness will be defined and explored in other, more complex, cereals such as wheat. Expected outcomes will be fundamental breakthroughs in understanding how plants respond to, and buffer, the effects of heat to lead to translational breeding strategies that bolster grain yield.Read moreRead less
Markov Field Theory applied to Sensor Networks Analysis and Design. Ad hoc and sensor networks have a wide range of applications in defence, emergency services and agriculture because they do not require telecommunications infrastructure such as base stations or access points, hence are relatively easy to deploy in harsh environments. This project aims at improving the theoretical understanding of sensor and ad hoc networks, which enable improvements in performance in such networks. Australian d ....Markov Field Theory applied to Sensor Networks Analysis and Design. Ad hoc and sensor networks have a wide range of applications in defence, emergency services and agriculture because they do not require telecommunications infrastructure such as base stations or access points, hence are relatively easy to deploy in harsh environments. This project aims at improving the theoretical understanding of sensor and ad hoc networks, which enable improvements in performance in such networks. Australian defence industry and emergency services will benefit from this research by gaining access to improved ad hoc communications networks. The agricultural sector will also benefit from the improved sensor networks in applications such as monitoring soil conditions, stock and crop levels. Read moreRead less
Dynamic phased array antennas for terahertz detection and ranging. The project aims to create reciprocal electrically-tuneable phased array antennas for terahertz waves. The antennas will comprise varactor diodes, analogue phase shifters, and dielectric resonator arrays to rapidly transmit and receive beams with high directivity and performance. The intended outcome is an integrated platform for short-range terahertz detection and ranging. This platform could be used in personal radar and drone- ....Dynamic phased array antennas for terahertz detection and ranging. The project aims to create reciprocal electrically-tuneable phased array antennas for terahertz waves. The antennas will comprise varactor diodes, analogue phase shifters, and dielectric resonator arrays to rapidly transmit and receive beams with high directivity and performance. The intended outcome is an integrated platform for short-range terahertz detection and ranging. This platform could be used in personal radar and drone-based radar, and high-contrast standoff detection. The project could benefit public security and welfare.Read moreRead less
Size matters, but at what cost? Role of male sex hormones in the placenta. This project aims to understand molecular pathways regulated by male sex hormones in the placenta that may contribute to sex-specific fetal growth and survival outcomes in response to reduced oxygen and/or glucose. Through this project, we expect to generate new knowledge of the mechanisms that drive sex-specific placental molecular function using interdisciplinary approaches. The application of this advanced understandin ....Size matters, but at what cost? Role of male sex hormones in the placenta. This project aims to understand molecular pathways regulated by male sex hormones in the placenta that may contribute to sex-specific fetal growth and survival outcomes in response to reduced oxygen and/or glucose. Through this project, we expect to generate new knowledge of the mechanisms that drive sex-specific placental molecular function using interdisciplinary approaches. The application of this advanced understanding of the sex-specific regulation of placental molecular function and fetal growth may be targeted in future studies to improve fetal growth outcomes in placental mammals such as livestock, domestic pets, and humans.Read moreRead less