Wiring the gut's nervous system: formation and maturation of synapses. This project aims to determine how nerve circuits controlling intestinal functions develop; specifically how communication between specific nerve cells is established once they appear in the embryonic gut. It will fill a major hole in existing knowledge of mechanisms regulating the development of normal digestive behaviours.
Discovery Early Career Researcher Award - Grant ID: DE130100223
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Characterisation of visceral afferent spinal cord pathways. Sensory nerves in the gut wall are key mediators of chronic visceral pain. This project will characterise how sensory nerves supplying the bowel connect to the spinal cord and the spinal circuits mediating pain perception, providing information to identify sensory pathways underlying visceral pain.