Elucidation Of Immune Mechanisms Underlying HSV Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$573,993.00
Summary
HSV-1 and -2 causes genital herpes, cold sores, encephalitis, potential fatal neonatal herpes, keratitis and blindness as well as severe disease in transplant patients. HSV infection also enhances the acquisition of HIV by 2-3 fold. Investigating the mechanism of immune response to HSV infection or components of HSV will assist in understanding immune control of HSV, HSV vaccine development, and assist in reducing in HIV spread.
Targeting Tumour-Stromal Interactions In Pancreatic Cancer
Funder
National Health and Medical Research Council
Funding Amount
$410,095.00
Summary
Pancreatic cancer claims five Australian lives every day and is one of the nations most lethal diseases. Despite aggressive treatment regimes, there has been no improvement in patient survival in the last decade. Evidence suggests that targeting cancer cells alone is not enough. The intense stromal reaction inhibits drug delivery and increases the aggressiveness of the tumours. Thus, depletion of the stroma or pancreatic stellate cells is a potential therapeutic target.
Initial Interactions Of Herpes Simplex Virus With Innate Immune Cells In Human Skin
Funder
National Health and Medical Research Council
Funding Amount
$522,589.00
Summary
Herpes simplex viruses 1 and 2 cause widespread and occasionally serious diseases including genital herpes, neonatal death and encephalitis. Current vaccine candidates are at best partially effective. This grant will examine the way that the virus enters, initially spreads within the skin and interacts with immune cells to help determine which cells should be stimulated by vaccines.
Fabrication of silicon solar cells in a Lunar-like vacuum environment. In-situ power generation on the Moon is essential for the advancement of space exploration and habitation. At present this involves transportation of solar cells to the Moon. This proposal aims to pave the way for manufacture of solar cells on the Moon from Lunar materials. Utilising the future extraction and purification of silicon, abundant in lunar regolith, the project will focus on fabrication of silicon solar cells. Thi ....Fabrication of silicon solar cells in a Lunar-like vacuum environment. In-situ power generation on the Moon is essential for the advancement of space exploration and habitation. At present this involves transportation of solar cells to the Moon. This proposal aims to pave the way for manufacture of solar cells on the Moon from Lunar materials. Utilising the future extraction and purification of silicon, abundant in lunar regolith, the project will focus on fabrication of silicon solar cells. This will provide power for: water mining, oxygen extraction, vehicles and habitats on the Moon and delivery of materials to Low Earth Orbit. The proposed research aims to develop solar cells that can be manufactured on the Moon, using materials abundant there, and techniques exploiting the natural vacuum of space.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100812
Funder
Australian Research Council
Funding Amount
$425,888.00
Summary
Is degradation of photovoltaic modules predictable and preventable? This project aims to determine the fundamental properties of the hydrogen related defect causing degradation of commercial solar modules and develop models to predict its impact. The defect causes up to 16% power loss and is likely to affect all photovoltaics due to the universal behaviour of hydrogen in semiconductors. Through new techniques combining deuterium (heavy hydrogen) and machine learning, the key project outcomes are ....Is degradation of photovoltaic modules predictable and preventable? This project aims to determine the fundamental properties of the hydrogen related defect causing degradation of commercial solar modules and develop models to predict its impact. The defect causes up to 16% power loss and is likely to affect all photovoltaics due to the universal behaviour of hydrogen in semiconductors. Through new techniques combining deuterium (heavy hydrogen) and machine learning, the key project outcomes are new knowledge of hydrogen behaviour, mitigation of degradation and predictive models to test and forecast the future output of affected modules. This is critical for system design and reliability, manufacturer warranty terms, investor returns, consumer confidence, and ultimately mitigating the climate crisis.Read moreRead less
Innovative high-efficiency hybrid technology for commercial solar cells. The purpose of this project is to develop improved photovoltaic devices of significantly higher efficiency and lower cost than conventional screen-printed solar cells. This in turn will contribute to greatly reduced electricity costs from non fossil-fuel based sources.
Discovery Early Career Researcher Award - Grant ID: DE170100620
Funder
Australian Research Council
Funding Amount
$390,000.00
Summary
Hydrogen passivation mechanisms in silicon solar cells. This project aims to understand hydrogen passivation mechanisms in silicon solar cells. Most silicon solar cells use low-quality wafers with defects that can reduce performance by >10%. Commercial devices use hydrogen to passivate defects and improve performance. Despite decades of research, these passivation mechanisms are controversial and industrial methods are ineffective. This project will investigate hydrogen charge-state control and ....Hydrogen passivation mechanisms in silicon solar cells. This project aims to understand hydrogen passivation mechanisms in silicon solar cells. Most silicon solar cells use low-quality wafers with defects that can reduce performance by >10%. Commercial devices use hydrogen to passivate defects and improve performance. Despite decades of research, these passivation mechanisms are controversial and industrial methods are ineffective. This project will investigate hydrogen charge-state control and transient hydrogenation processes, and correlate reaction rates and material properties. This should improve the understanding of hydrogen passivation mechanisms and lead to more effective hydrogenation processes that potentially reduce greenhouse gas emissions and the cost of sustainable electricity.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150100268
Funder
Australian Research Council
Funding Amount
$340,000.00
Summary
Advanced Recombination-based Loss Analysis Methods for Solar Cells. Photovoltaic (PV) solar cells are too expensive to become a viable solution for the challenges facing humanity. Increasing solar cell efficiency can reduce the cost of PV-generated power. Improved efficiency requires the ability to identify and quantify loss mechanisms, many of which are recombination related. Thus, innovative analysis methods need to be developed to facilitate improved understanding and identification of variou ....Advanced Recombination-based Loss Analysis Methods for Solar Cells. Photovoltaic (PV) solar cells are too expensive to become a viable solution for the challenges facing humanity. Increasing solar cell efficiency can reduce the cost of PV-generated power. Improved efficiency requires the ability to identify and quantify loss mechanisms, many of which are recombination related. Thus, innovative analysis methods need to be developed to facilitate improved understanding and identification of various loss mechanisms. The project aims to investigate recombination processes that deteriorate solar cells performance, using a novel measurement system in combination with advanced simulation tools. The project aims to assist with development of advanced processes to improve device performance.Read moreRead less
Industrial High Efficiency Solar Cells. Photovoltaics is a promising candidate for sustainable energy generation, with Australia well-placed to capture the economic and environmental benefits from maintaining its strong position with this technology. Suntech, a world-leader in silicon solar cell production with US$2 billion annual revenue, will provide a “high profile” showplace for the developed patterning technology. This will enhance commercial opportunities arising from the project and confi ....Industrial High Efficiency Solar Cells. Photovoltaics is a promising candidate for sustainable energy generation, with Australia well-placed to capture the economic and environmental benefits from maintaining its strong position with this technology. Suntech, a world-leader in silicon solar cell production with US$2 billion annual revenue, will provide a “high profile” showplace for the developed patterning technology. This will enhance commercial opportunities arising from the project and confirm Australia’s reputation as a world leader in innovative photovoltaic research. This reputation attracts high-calibre professionals to Australia, stimulates local research and will provide opportunities for local manufacturing to exploit the technology developed as part of this project.Read moreRead less
A Novel Macrophage Lineage In Inflammation And Cancer
Funder
National Health and Medical Research Council
Funding Amount
$772,857.00
Summary
Macrophages are an important haematopoietic cell type that has been implicated in inflammatory and cancerous diseases. In our preliminary work we have discovered a new macrophage subset, termed the perivascular macrophage, in breast cancer. The aim of this proposal is to investigate the origin of these cells, and the role they play in breast cancer. This will tell us how we might be able to manipulate the functions of these cells in order to curtail breast cancer progression.